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(2003) Hypogonadotropic hypogonadism due to loss of function of the KiSS1-derived peptide receptor GPR54. Proc Natl Acad Sci U S A 100: 10972\u201310976.","DOI":"10.1073\/pnas.1834399100"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2 Seminara SB, Messager S, Chatzidaki EE, Thresher RR, Acierno JS Jr, et al. (2003) The GPR54 gene as a regulator of puberty. N Engl J Med 349: 1614\u20131627.","DOI":"10.1056\/NEJMoa035322"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3 Pinilla L, Aguilar E, Dieguez C, Millar RP, Tena-Sempere M (2012) Kisspeptins and reproduction: physiological roles and regulatory mechanisms. Physiol Rev 92: 1235\u20131316.","DOI":"10.1152\/physrev.00037.2010"},{"key":"4","doi-asserted-by":"publisher","unstructured":"4 Kauffman AS, Gottsch ML, Roa J, Byquist AC, Crown A, et al. (2007) Sexual differentiation of Kiss1 gene expression in the brain of the rat. 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(2004) Developmental and hormonally regulated messenger ribonucleic acid expression of KiSS-1 and its putative receptor, GPR54, in rat hypothalamus and potent luteinizing hormone-releasing activity of KiSS-1 peptide. Endocrinology 145: 4565\u20134574.","DOI":"10.1210\/en.2004-0413"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8 Wakabayashi Y, Nakada T, Murata K, Ohkura S, Mogi K, et al. (2010) Neurokinin B and dynorphin A in kisspeptin neurons of the arcuate nucleus participate in generation of periodic oscillation of neural activity driving pulsatile gonadotropin-releasing hormone secretion in the goat. J Neurosci 30: 3124\u20133132.","DOI":"10.1523\/JNEUROSCI.5848-09.2010"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9 Mottram JC, Cramer W (1923) On the general effects of exposure to radium on metabolism and tumour growth in the rat and the special effects on testis and pituitary. 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(2016) Divergent regulation of ER and kiss genes by 17\u03b2-estradiol in hypothalamic ARC <i>versus<\/i> AVPV models. Mol Endocrinol 30: 217\u2013233.","DOI":"10.1210\/me.2015-1189"},{"key":"35","doi-asserted-by":"publisher","unstructured":"35 Lewis KA, Gray PC, Blount AL, MacConell LA, Wiater E, et al. (2000) Betaglycan binds inhibin and can mediate functional antagonism of activin signalling. Nature 404: 411\u2013414.","DOI":"10.1038\/35006129"},{"key":"36","doi-asserted-by":"crossref","unstructured":"36 Makanji Y, Zhu J, Mishra R, Holmquist C, Wong WP, et al. (2014) Inhibin at 90: from discovery to clinical application, a historical review. Endocr Rev 35: 747\u2013794.","DOI":"10.1210\/er.2014-1003"},{"key":"37","doi-asserted-by":"publisher","unstructured":"37 Roberts V, Meunier H, Vaughan J, Rivier J, Rivier C, et al. (1989) Production and regulation of inhibin subunits in pituitary gonadotropes. 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