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Proc Univ Otago M School 34: 11\u201312."},{"key":"2","doi-asserted-by":"crossref","unstructured":"2 Adams DD (1965) Pathogenesis of the hyperthyroidism of Graves\u2019s disease. Br Med J 1: 1015\u20131019.","DOI":"10.1136\/bmj.1.5441.1015"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3 Dorrington KJ, Munro DS (1966) The long-acting thyroid stimulator. Clin Pharmacol Ther 7: 788\u2013806.","DOI":"10.1002\/cpt196676788"},{"key":"4","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/S0140-6736(74)91815-7","volume":"2","author":"BR Smith","year":"1974","unstructured":"4 Smith BR, Hall R (1974) Thyroid-stimulating immunoglobulins in Graves\u2019 disease. Lancet 2: 427\u2013431.","journal-title":"The Lancet","ISSN":"https:\/\/id.crossref.org\/issn\/0140-6736","issn-type":"print"},{"key":"5","doi-asserted-by":"publisher","unstructured":"5 Porter RR (1958) Separation and isolation of fractions of rabbit gamma-globulin containing the antibody and antigenic combining sites. Nature 182: 670\u2013671.","DOI":"10.1038\/182670a0"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6 Fleischman JB, Porter RR, Press EM (1963) The arrangement of the peptide chains in gamma-globulin. Biochem J 88: 220\u2013228.","DOI":"10.1042\/bj0880220"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7 Smith BR, Dorrington KJ, Munro DS (1969) The thyroid-stimulating properties of long-acting thyroid stimulator gamma G-globulin subunits. Biochim Biophys Acta 192: 277\u2013285.","DOI":"10.1016\/0304-4165(69)90366-3"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8 Smith BR (1970) The interaction of the long-acting thyroid stimulator (LATS) with thyroid tissue <i>in vitro<\/i>. J Endocrinol 46: 45\u201354.","DOI":"10.1677\/joe.0.0460045"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9 Smith BR (1971) Characterisation of long-acting thyroid stimulator gamma-G binding protein. Biochim Biophys Acta 229: 649\u2013662.","DOI":"10.1016\/0005-2795(71)90281-9"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10 Smith BR, Munro DS (1970) The nature of the interaction between thyroid stimulating gamma G-globulin (long-acting thyroid stimulator) and thyroid tissue. Biochim Biophys Acta 208: 285\u2013293.","DOI":"10.1016\/0304-4165(70)90247-3"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11 Rees Smith B, McLachlan SM, Furmaniak J (1988) Autoantibodies to the thyrotropin receptor. Endocr Rev 9: 106\u2013121.","DOI":"10.1210\/edrv-9-1-106"},{"key":"12","doi-asserted-by":"publisher","unstructured":"12 Mukhtar ED, Smith BR, Pyle GA, Hall R, Vice P (1975) Relation of thyroid-stimulating immunoglobulins to thyroid function and effects of surgery, radioiodine, and antithyroid drugs. Lancet 1: 713\u2013715.","DOI":"10.1016\/S0140-6736(75)91629-3"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13 Clague R, Mukhtar ED, Pyle GA, Nutt J, Clark F, et al. (1976) Thyroid-stimulating immunoglobulins and the control of thyroid function. J Clin Endocrinol Metab 43: 550\u2013556.","DOI":"10.1210\/jcem-43-3-550"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14 Endo K, Kasagi K, Konishi J, Ikekubo K, Okuno T, et al. (1978) Detection and properties of TSH-binding inhibitor immunoglobulins in patients with Graves\u2019 disease and Hashimoto\u2019s thyroiditis. J Clin Endocrinol Metab 46: 734\u2013739.","DOI":"10.1210\/jcem-46-5-734"},{"key":"15","doi-asserted-by":"publisher","unstructured":"15 Smith BR, Bolton J, Young S, Collyer A, Weeden A, et al. (2004) A new assay for thyrotropin receptor autoantibodies. Thyroid 14: 830\u2013835.","DOI":"10.1089\/1050725042451248"},{"key":"16","doi-asserted-by":"publisher","unstructured":"16 Yoshimura Noh J, Miyazaki N, Ito K, Takeda K, Hiramatsu S, et al. (2008) Evaluation of a new rapid and fully automated electrochemiluminescence immunoassay for thyrotropin receptor autoantibodies. Thyroid 18: 1157\u20131164.","DOI":"10.1089\/thy.2008.0119"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17 Schott M, Hermsen D, Broecker-Preuss M, Casati M, Mas JC, et al. (2009) Clinical value of the first automated TSH receptor autoantibody assay for the diagnosis of Graves\u2019 disease (GD): an international multicentre trial. <i>Clin Endocrinol (Oxf)<\/i> 71: 566\u2013573.","DOI":"10.1111\/j.1365-2265.2008.03512.x"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18 Kasagi K, Konishi J, Iida Y, Ikekubo K, Mori T, et al. (1982) A new <i>in vitro<\/i> assay for human thyroid stimulator using cultured thyroid cells: effect of sodium chloride on adenosine 3&apos;,5&apos;-monophosphate increase. J Clin Endocrinol Metab 54: 108\u2013114.","DOI":"10.1210\/jcem-54-1-108"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19 Takasu N, Matsushita M (2012) Changes of TSH-Stimulation Blocking Antibody (TSBAb) and Thyroid Stimulating Antibody (TSAb) over 10 years in 34 TSBAb-positive patients with hypothyroidism and in 98 TSAb-positive Graves\u2019 patients with hyperthyroidism: reevaluation of TSBAb and TSAb in TSH-Receptor-Antibody (TRAb)-positive patients. J Thyroid Res 2012: 182176.","DOI":"10.1155\/2012\/182176"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20 Shewring G, Smith BR (1982) An improved radioreceptor assay for TSH receptor antibodies. Clin Endocrinol (Oxf) 17: 409\u2013417.","DOI":"10.1111\/j.1365-2265.1982.tb01607.x"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21 Southgate K, Creagh F, Teece M, Kingswood C, Rees Smith B (1984) A receptor assay for the measurement of TSH receptor antibodies in unextracted serum. 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(2021) Blocking the thyrotropin receptor with K1-70 in a patient with follicular thyroid cancer, Graves\u2019 disease, and Graves\u2019 ophthalmopathy. Thyroid 31: 1597\u20131602.","DOI":"10.1089\/thy.2021.0053"},{"key":"56","doi-asserted-by":"publisher","unstructured":"56 Noh JY, Watanabe N, Ito K, Tsuiki M, Ishihara Y, et al. (2025) Safety, pharmacokinetics, and potential benefits of TSH-receptor-specific monoclonal autoantibody K1-70(TM) in Japanese Graves\u2019 disease patients: results of a phase 1 trial. Endocr J. doi: 10.1507\/endocrj.EJ25-0043 Online ahead of print.","DOI":"10.1507\/endocrj.EJ25-0043"},{"key":"57","doi-asserted-by":"crossref","unstructured":"57 Miller JL, Tate CG (2011) Engineering an ultra-thermostable \u03b2(1)-adrenoceptor. J Mol Biol 413: 628\u2013638.","DOI":"10.1016\/j.jmb.2011.08.057"},{"key":"58","doi-asserted-by":"crossref","unstructured":"58 Holthoff HP, Uhland K, Kovacs GL, Reimann A, Adler K, et al. 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