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Xu H, Barnes GT, Yang Q, Tan G, Yang D, Chou CJ, Sole J, Nichols A, Ross JS, Tartaglia LA, Chen H (2003) Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. <I>J Clin Invest <\/I>112: 1821-1830.","DOI":"10.1172\/JCI200319451"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Weisberg SP, McCann D, Desai M, Rosenbaum M, Leibel RL, Ferrante AWJ (2003) Obesity is associated with macrophage accumulation in adipose tissue. <I>J Clin Invest <\/I>112: 1796-1808.","DOI":"10.1172\/JCI200319246"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Arnaldi G, Angeli A, Atkinson AB, Bertagna X, Cavagnini F, Chrousos GP, Fava GA, Findling JW, Gaillard RC, Grossman AB, Kola B, Lacroix A, Mancini T, Mantero F, Newell-Price J, Nieman LK, Sonino N, Vance ML, Giustina A, Boscaro M (2003) Diagnosis and complications of Cushing&rsquo;s syndrome: a consensus statement. <I>J Clin Endocrinol Metab <\/I>88: 5593-5602.","DOI":"10.1210\/jc.2003-030871"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Masuzaki H, Paterson J, Shinyama H, Morton NM, Seckl JR, Flier JS (2001) A transgenic model of visceral obesity and the metabolic syndrome. <I>Science <\/I>94: 2166-2170.","DOI":"10.1126\/science.1066285"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Tomlinson JW, Walker EA, Bujalska IJ, Draper N, Lavery GG, Cooper MS, Hewison M, Stewart PM (2004) 11&beta;-hydroxysteroid dehydrogenase type 1: a tissue-specific regulator of glucocorticoid response. <I>Endocrine Reviews <\/I>25: 831-866.","DOI":"10.1210\/er.2003-0031"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Shojima N, Sakoda H, Ogihara T, Fujishiro M, Katagiri H, Anai M, Onishi Y, Ono H, Inukai K, Abe M, Fukushima Y, Kikuchi M, Oka Y, Asano T (2002) Humoral regulation of resistin expression in 3T3-L1 and mouse adipose cells. <I>Diabetes <\/I>51: 1737-1744.","DOI":"10.2337\/diabetes.51.6.1737"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Krsek M, Silha JV, Jezkova J, Hana V, Marek J, Weiss V, Stepan JJ, Murphy LJ (2004) Adipokine levels in Cushing&rsquo;s syndrome: elevated resistin levels in female patients with Cushing&rsquo;s syndrome. <I>Clin Endocrinol <\/I>60: 350-357.","DOI":"10.1111\/j.1365-2265.2003.01987.x"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Hu E, Liang P, Spiegelman BM (1996) AdipoQ is a novel adipose-specific gene dysregulated in obesity. <I>J Biol Chem <\/I>271: 10697-10703.","DOI":"10.1074\/jbc.271.18.10697"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Maeda K, Okubo K, Shimomura I, Funahashi T, Matsuzawa Y, Matsubara K (1996) cDNA cloning and expression of a novel adipose specific collagen-like factor, apM1 (AdiPose Most abundant Gene transcript 1). <I>Biochem Biophys Res Commun <\/I>221: 286-289.","DOI":"10.1006\/bbrc.1996.0587"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. 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Yatagai T, Nagasaka S, Taniguchi A, Fukushima M, Nakamura T, Kuroe A, Nakai Y, Ishibashi S (2003) Hypoadiponectinemia is associated with visceral fat accumulation and insulin resistance in Japanese men with type 2 diabetes mellitus. <I>Metabolism <\/I>52: 1274-1278.","DOI":"10.1016\/S0026-0495(03)00195-1"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Lindsay RS, Funahashi T, Hanson RL, Matsuzawa Y, Tanaka S, Tataranni PA, Knowler WC, Krakoff J (2002) Adiponectin and development of type 2 diabetes in the Pima Indian population. <I>Lancet <\/I>360: 57-58.","DOI":"10.1016\/S0140-6736(02)09335-2"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. Spranger J, Kroke A, Mohlig M, Bergmann MM, Ristow M, Boeing H, Pfeiffer AF (2003) Adiponectin and protection against type 2 diabetes mellitus. <I>Lancet <\/I>361: 226-228.","DOI":"10.1016\/S0140-6736(03)12255-6"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. 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Bruun JM, Jihn AS, Verdich C, Pedersen SB, Toubro S, Astrup A, Richelsen B (2003) Regulation of adiponectin by adipose tissue-derived cytokines: <I>in vivo <\/I>and <I>in vitro <\/I>investigations in humans. <I>Am J Physiol Endocrinol Metab <\/I>285: E527-533.","DOI":"10.1152\/ajpendo.00110.2003"},{"key":"54","doi-asserted-by":"crossref","unstructured":"28. Yamauchi T, Kamon J, Waki H, Terauchi Y, Kubota N, Hara K, Mori Y, Ide T, Murakami K, Tsuboyama- Kasaoka N, Ezaki O, Akanuma Y, Gavrilova O, Vinson C, Reitman ML, Kagechika H, Shudo K, Yoda M, Nakano Y, Tobe K, Nagai R, Kimura S, Tomita M, Froguel P, Kadowaki T (2001) The fat-derived hormone adoponectin reverses insulin resistance associated with both lipoatrophy and obesity. <I>Nat Med <\/I>7: 941-946.","DOI":"10.1038\/90984"},{"key":"55","doi-asserted-by":"crossref","unstructured":"29. Yamauchi T, Kamon J, Waki H, Imai Y, Shimozawa N, Hioki K, Uchida S, Ito Y, Takakuwa K, Matsui J, Takata M, Eto K, Terauchi Y, Komeda K, Tsunoda M, Murakami K, Ohnishi Y, Naitoh T, Yamamura K, Ueyama Y, Froguel P, Kimura S, Nagai R, Kadowaki T (2003) Globular adiponectin protected ob\/ob mice from diabetes and apoE-deficient mice from atherosclerosis. <I>J Biol Chem <\/I>278: 2461-2468.","DOI":"10.1074\/jbc.M209033200"},{"key":"56","doi-asserted-by":"crossref","unstructured":"30. Tsuchida A, Yamauchi T, Ito Y, Hada Y, Maki T, Takekawa S, Kamon J, Kobayashi M, Suzuki R, Hara K, Kubota N, Terauchi Y, Froguel P, Nakae J, Kasuga M, Accili D, Tobe K, Ueki K, Nagai R, Kadowaki T (2004) Insulin\/Foxo1 pathway regulates expression levels of adiponectin receptors and adiponectin sensitivity. <I>J Biol Chem <\/I>279: 30817-30822.","DOI":"10.1074\/jbc.M402367200"},{"key":"57","doi-asserted-by":"crossref","unstructured":"31. Libe R, Morpurgo PS, Cappiello V, Maffini A, Bondioni S, Locatelli M, Zavanone M, Beck-Peccoz P, Spada A (2005) Ghrelin and adiponectin in patients with Cushing&rsquo;s disease before and after successful transsphenoidal surgery. <I>Clin Endocrinol <\/I>62: 30-36.","DOI":"10.1111\/j.1365-2265.2004.02169.x"},{"key":"58","doi-asserted-by":"crossref","unstructured":"32. Darman P, Dadoun F, Boullu-Ciocca S, Grino M, Alessi MC, Dutour A (2006) Insulin resistance induced by hydrocortisone is increased in patients with abdominal obesity. <I>Am J Physiol Endocrinol Metab <\/I>291: E995-E1002.","DOI":"10.1152\/ajpendo.00654.2005"},{"key":"59","doi-asserted-by":"crossref","unstructured":"33. Uchida HA, Nakayama Y, Kaihara M, Norii H, Hanayama Y, Sugiyama H, Maeshima Y, Yamasaki Y, Makino H (2006) Steroid pulse therapy impaired endothelial function while increasing plasma high molecule adiponectin concentration in patients with IgA nephropathy. <I>Nephrol Dial Transplant <\/I>21: 3475-3480.","DOI":"10.1093\/ndt\/gfl423"},{"key":"60","doi-asserted-by":"crossref","unstructured":"34. Wang ZV, Schraw TD, Kim JY, Khan T, Rajala MW, Follenzi A, Scherer PE (2007) Secretion of the adipocyte- specific secretory protein adiponectin critically depends on thiol-mediated protein retension. <I>Mol Cell Biol <\/I>27: 3716-3731.","DOI":"10.1128\/MCB.00931-06"},{"key":"61","unstructured":"35. Wang Y, Lam KS, Yau MH, Xu A (2008) Posttranslational modifications of adiponectin: mechanisms and functional implications. <I>Biochem J <\/I>409: 623-633. A, Vaughan J, Sawchenko PE, Vale WW (1992) Development of Cushing&rsquo;s syndrome in corticotropin-releasing factor transgenic mice. <I>Endocrinology <\/I>130: 3378-3386."},{"key":"62","doi-asserted-by":"crossref","unstructured":"27. Bruun JM, Jihn AS, Verdich C, Pedersen SB, Toubro S, Astrup A, Richelsen B (2003) Regulation of adiponectin by adipose tissue-derived cytokines: <I>in vivo <\/I>and <I>in vitro <\/I>investigations in humans. <I>Am J Physiol Endocrinol Metab <\/I>285: E527-533.","DOI":"10.1152\/ajpendo.00110.2003"},{"key":"63","doi-asserted-by":"crossref","unstructured":"28. 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