{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T16:25:33Z","timestamp":1791044733946,"version":"4.1.0"},"reference-count":55,"publisher":"Japan Endocrine Society","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Endocr J"],"published-print":{"date-parts":[[2011]]},"DOI":"10.1507\/endocrj.k11e-131","type":"journal-article","created":{"date-parts":[[2011,10,6]],"date-time":"2011-10-06T05:20:37Z","timestamp":1317878437000},"page":"1003-1012","source":"Crossref","is-referenced-by-count":45,"title":["Fasting reduces the kiss1 mRNA levels in the caudal hypothalamus of gonadally intact adult female rats"],"prefix":"10.1507","volume":"58","author":[{"given":"Toshiya","family":"Matsuzaki","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima 770-8503, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeshi","family":"Iwasa","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima 770-8503, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riyo","family":"Kinouchi","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima 770-8503, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinobu","family":"Yoshida","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima 770-8503, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiro","family":"Murakami","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima 770-8503, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ganbat","family":"Gereltsetseg","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima 770-8503, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoshi","family":"Yamamoto","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima 770-8503, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akira","family":"Kuwahara","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima 770-8503, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiyuki","family":"Yasui","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima 770-8503, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minoru","family":"Irahara","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima 770-8503, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"386","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1. Cagampang FR, Maeda KI, Tsukamura H, Ohkura S, Ota K (1991) Involvement of ovarian steroids and endogenous opioids in the fasting-induced suppression of pulsatile LH release in ovariectomized rats. J Endocrinol<\/i> 129: 321-328.","DOI":"10.1677\/joe.0.1290321"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-8993(01)02157-6"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1530\/jrf.0.0740057"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Knuth UA, Friesen HG (1983) Starvation induced anoestrus: effect of chronic food restriction on body weight, its influence on oestrous cycle and gonadotrophin secretion in rats. Acta Endocrinol<\/i> 104: 402-409.","DOI":"10.1530\/acta.0.1040402"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Bronson FH, Marsteller FA (1985) Effect of short-term food deprivation on reproduction in female mice. Biol Reprod<\/i> 33: 660-667.","DOI":"10.1095\/biolreprod33.3.660"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1038\/382250a0"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Castellano JM, Navarro VM, Fernandez-Fernandez R, Nogueiras R, Tovar S, Roa J, Vazquez MJ, Vigo E, Casanueva FF, Aguilar E, Pinilla L, Dieguez C, Tena-Sempere M (2005) Change in hypothalamic KiSS-1 system and restoration of pubertal activation of the reproductive axis by kisspeptin in undernutrition. Endocrinology<\/i> 146: 3917-3925.","DOI":"10.1210\/en.2005-0337"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Tena-Sempere M (2007) Roles of ghrelin and leptin in the control of reproductive function. Neuroendocrinology<\/i> 86: 229-241.","DOI":"10.1159\/000108410"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1210\/en.138.2.855"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Bi S, Moran TH (2003) Response to acute food deprivation in OLETF rats lacking CCK-A receptors. Physiol Behav<\/i> 79: 655-661.","DOI":"10.1016\/S0031-9384(03)00173-2"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Kaynard AH, Pau KY, Hess DL, Spies HG (1990) Third-ventricular infusion of neuropeptide Y suppresses luteinizing hormone secretion in ovariectomized rhesus macaques. Endocrinology<\/i> 127: 2437-2344.","DOI":"10.1210\/endo-127-5-2437"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. McDonald JK (1990) Role of neuropeptide Y in reproductive function. Ann N Y Acad Sci <\/i>611: 258-272.","DOI":"10.1111\/j.1749-6632.1990.tb48937.x"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.94.3.1023"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod60.2.216"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2826.2006.01417.x"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1210\/en.2004-0431"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1159\/000083140"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0409330102"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Navarro VM, Castellano JM, Fernandez-Fernandez R, Tovar S, Roa J, Mayen A, Nogueiras R, Vazquez MJ, Barreiro ML, Magni P, Aguilar E, Dieguez C, Pinilla L, Tena-Sempere M (2005) Characterization of the potent luteinizing hormone releasing activity of KiSS-1 peptide, the natural ligand of GPR54. Endocrinology<\/i> 146: 156-163.","DOI":"10.1210\/en.2004-0836"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0409822102"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. Navarro VM, Fernandez-Fernandez R, Castellano JM, Roa J, Mayen A, Barreiro ML, Gaytan F, Aguilar E, Pinilla L, Dieguez C, Tena-Sempere M (2004) Advanced vaginal opening and precocious activation of the reproductive axis by KiSS-1 peptide, the endogenous ligand of GPR54. J Physiol<\/i> 561: 379-386.","DOI":"10.1113\/jphysiol.2004.072298"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1834399100"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa035322"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1007\/s11154-007-9032-6"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25. Ohkura S, Uenoyama Y, Yamada S, Homma T, Takase K, Inoue K, Maeda KI, Tsukamura H (2009) Physiological role of metastin\/kisspeptin in regulating gonadotrophin-releasing hormone (GnRH) secretion in female rats. Peptides<\/i> 30: 49-56.","DOI":"10.1016\/j.peptides.2008.08.004"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26. Smith JT, Popa SM, Clifton DK, Hoffman GE, Steiner RA (2006) Kiss1 neurons in the forebrain as central processors for generating the preovulatory luteinizing hormone surge. J Neurosci<\/i> 26: 6687-6694.","DOI":"10.1523\/JNEUROSCI.1618-06.2006"},{"key":"27","doi-asserted-by":"publisher","DOI":"10.1210\/en.2005-0195"},{"key":"28","doi-asserted-by":"crossref","unstructured":"28. Smith JT, Clifton DK, Steiner RA (2006) Regulation of the neuroendocrine reproductive axis by kisspeptin-GPR54 signaling. Reproduction<\/i> 131: 623-630.","DOI":"10.1530\/rep.1.00368"},{"key":"29","doi-asserted-by":"publisher","DOI":"10.1210\/en.2007-0961"},{"key":"30","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1569-09.2009"},{"key":"31","doi-asserted-by":"crossref","unstructured":"31. Krajewski SJ, Burke MC, Anderson MJ, McMullen NT, Rance NE (2010) Forebrain projections of arcuate neurokinin B neurons demonstrated by anterograde tract-tracing and monosodium glutamate lesions in the rat. Neuroscience<\/i> 166: 680-697.","DOI":"10.1016\/j.neuroscience.2009.12.053"},{"key":"32","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.5848-09.2010"},{"key":"33","doi-asserted-by":"publisher","DOI":"10.1038\/ng.306"},{"key":"34","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2009-2320"},{"key":"35","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2009-2600"},{"key":"36","doi-asserted-by":"crossref","unstructured":"36. Brown RE, Imran SA, Ur E, Wilkinson M (2008) KiSS-1 mRNA in adipose tissue is regulated by sex hormones and food intake. Mol Cell Endocrinol<\/i> 281: 64-72.","DOI":"10.1016\/j.mce.2007.10.011"},{"key":"37","doi-asserted-by":"crossref","unstructured":"37. Luque RM, Kineman RD, Tena-Sempere M (2007) Regulation of hypothalamic expression of KiSS-1 and GPR54 genes by metabolic factors: analyses using models and a cell line. Endocrinology<\/i> 148: 4601-4611.","DOI":"10.1210\/en.2007-0500"},{"key":"38","doi-asserted-by":"publisher","DOI":"10.1677\/JOE-10-0129"},{"key":"39","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2826.2008.01757.x"},{"key":"40","doi-asserted-by":"crossref","unstructured":"40. Castellano JM, Navarro VM, Fernandez-Fernandez R, Roa J, Vigo E, Pineda R, Dieguez C, Aguilar E, Pinilla L, Tena-Sempere M (2006) Expression of hypothalamic KiSS-1 system and rescue of defective gonadotropic responses by kisspeptin in streptozotocin-induced diabetic male rats. Diabetes<\/i> 55: 2602-2610.","DOI":"10.2337\/db05-1584"},{"key":"41","doi-asserted-by":"crossref","unstructured":"41. Krajewski SJ, Anderson MJ, Iles-shih L, Chen KJ, Urbanski HF, Rance NE (2005) Morphologic evidence that neurokinin B modulates gonadotrophin-releasing hormone secretion via neurokinin 3 receptors in the rat median eminence. J Comp Neurol<\/i> 489: 372-386.","DOI":"10.1002\/cne.20626"},{"key":"42","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2826.2009.01951.x"},{"key":"43","doi-asserted-by":"crossref","unstructured":"43. Navarro VM, Castellano JM, McConkey SM, Pineda R, Ruiz-Pino F, Pinilla L, Clifton DK, Tena-Sempere M, Steiner RA (2011) Interactions between kisspeptin and neurokinin B in the control of GnRH secretion in the female rat. Am J Physiol Endocrinol Metab<\/i> 300: E202-E210.","DOI":"10.1152\/ajpendo.00517.2010"},{"key":"44","doi-asserted-by":"publisher","DOI":"10.1210\/en.2010-0022"},{"key":"45","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2010.08.059"},{"key":"46","doi-asserted-by":"publisher","DOI":"10.1210\/en.2006-1529"},{"key":"47","doi-asserted-by":"crossref","unstructured":"47. Forbes S, Li XF, Kinsey-Jones J, O’Byrne K (2009) Effects of ghrelin on kisspeptin mRNA expression in the hypothalamic medial preoptic area and pulsatile luteinizing hormone secretion in the female rat. Neurosci Lett<\/i> 460: 143-147.","DOI":"10.1016\/j.neulet.2009.05.060"},{"key":"48","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2826.2008.01807.x"},{"key":"49","doi-asserted-by":"publisher","DOI":"10.1262\/jrd.18146"},{"key":"50","doi-asserted-by":"publisher","DOI":"10.1006\/bbrc.1999.1573"},{"key":"51","doi-asserted-by":"publisher","DOI":"10.1006\/bbrc.2001.4328"},{"key":"52","doi-asserted-by":"crossref","unstructured":"52. Iwasa T, Matsuzaki T, Kiyokawa M, Shimizu F, Minakuchi M, Kuwahara A, Maegawa M, Yasui T, Irahara M (2007) The type 2 corticosterone-releasing hormone receptor mediates orexin A-induced luteinizing hormone suppression in ovariectomised rats. J Neuroendocrinol<\/i> 19: 732-738.","DOI":"10.1111\/j.1365-2826.2007.01583.x"},{"key":"53","doi-asserted-by":"crossref","unstructured":"53. Ogata R, Matsuzaki T, Iwasa T, Kiyokawa M, Tanaka N, Kuwahara A, Yasui T, Irahara M (2009) Hypothalamic ghrelin suppresses pulsatile secretion of luteinizing hormone via β-endorphin in ovariectomized rats. Neuroendocrinology<\/i> 90: 364-370.","DOI":"10.1159\/000257421"},{"issue":"5","key":"54","first-page":"467","volume":"129","year":"1993","ISSN":"https:\/\/id.crossref.org\/issn\/0001-5598","issn-type":"print"},{"key":"55","doi-asserted-by":"publisher","DOI":"10.1530\/eje.0.1380198"}],"container-title":["Endocrine Journal"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.jstage.jst.go.jp\/article\/endocrj\/58\/11\/58_K11E-131\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,13]],"date-time":"2021-04-13T06:56:35Z","timestamp":1618296995000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.jstage.jst.go.jp\/article\/endocrj\/58\/11\/58_K11E-131\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011]]},"references-count":55,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2011]]}},"URL":"https:\/\/doi.org\/10.1507\/endocrj.k11e-131","relation":{},"ISSN":["0918-8959","1348-4540"],"issn-type":[{"value":"0918-8959","type":"print"},{"value":"1348-4540","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011]]}}}