{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,11,5]],"date-time":"2022-11-05T05:19:02Z","timestamp":1667625542487},"reference-count":0,"publisher":"European Association of Cardiothoracic Surgery (EACTS Publishing Ltd)","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["MMCTS"],"published-print":{"date-parts":[[2022,11,4]]},"abstract":"<jats:p>The recent CE mark approval of a novel transapical transcatheter beating-heart replacement system, anchored by an apical pad, expanded the therapeutic options for patients with a significantly diseased mitral valve who are not eligible for conventional surgery. However, this self-expandable bioprosthesis is\u2014despite promising data from the first European real-world experience\u2014not approved for patients with severe mitral annular calcification. In this video tutorial, we provide a step-by-step description of an off-label transapical mitral valve replacement in a patient with severe degenerative mitral valve disease and limited alternative treatment options.<\/jats:p>","DOI":"10.1510\/mmcts.2022.082","type":"journal-article","created":{"date-parts":[[2022,11,4]],"date-time":"2022-11-04T12:37:43Z","timestamp":1667565463000},"source":"Crossref","is-referenced-by-count":0,"title":["Off-label transapical beating-heart transcatheter mitral valve replacement in severe mitral annular calcification"],"prefix":"10.1510","member":"10966","published-online":{"date-parts":[[2022,11,4]]},"container-title":["Multimedia Manual of Cardio-Thoracic Surgery"],"original-title":[],"deposited":{"date-parts":[[2022,11,4]],"date-time":"2022-11-04T12:37:44Z","timestamp":1667565464000},"score":1,"resource":{"primary":{"URL":"https:\/\/mmcts.org\/case-report\/1761"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11,4]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1510\/mmcts.2022.082","relation":{},"ISSN":["1813-9175"],"issn-type":[{"value":"1813-9175","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,11,4]]}}}