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Patients with pulmonary hypertension often face a considerable delay in diagnosis due to the rarity of the disease and nonspecific symptoms of dyspnea, fatigue, and exercise limitation. Cardiopulmonary exercise testing may be suggestive of pulmonary hypertension in patients with evidence of both circulatory impairment and ventilatory inefficiency. Other factors, such as mechanical ventilatory constraints from dynamic hyperinflation and peripheral muscle dysfunction, contribute to the profound dyspnea during exercise experienced by many patients with pulmonary hypertension. In patients with pulmonary arterial hypertension or chronic thromboembolic pulmonary hypertension, several exercise variables, such as low peak V.o2, high Vd\/Vt, and high V.e\/V.co2, have proven to be useful in establishing the severity of functional impairment, predicting prognosis, and assessing the efficacy of interventions.<\/jats:p>","DOI":"10.1513\/annalsats.201610-788fr","type":"journal-article","created":{"date-parts":[[2017,4,4]],"date-time":"2017-04-04T16:05:59Z","timestamp":1491321959000},"page":"S84-S92","source":"Crossref","is-referenced-by-count":104,"title":["Cardiopulmonary Exercise Testing in Pulmonary Hypertension"],"prefix":"10.1093","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0615-4575","authenticated-orcid":false,"given":"Jason","family":"Weatherald","sequence":"first","affiliation":[{"name":"Division of Respiratory Medicine, Department of Medicine, University of Calgary, Calgary, Alberta, Canada"},{"name":"University Paris-Sud, Universit\u00e9 Paris-Saclay, Le Kremlin-Bic\u00eatre, France"},{"name":"Service de Pneumologie, H\u00f4pital Bic\u00eatre, Assistance Publique-H\u00f4pitaux de Paris, Le Kremlin-Bic\u00eatre, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefania","family":"Farina","sequence":"additional","affiliation":[{"name":"Centro Cardiologico Monzino, Istituto di Ricovero e Cura a Carattere Scientifico, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noemi","family":"Bruno","sequence":"additional","affiliation":[{"name":"Centro Cardiologico Monzino, Istituto di Ricovero e Cura a Carattere Scientifico, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierantonio","family":"Laveneziana","sequence":"additional","affiliation":[{"name":"Sorbonne Universit\u00e9s, Universit\u00e9 Pierre et Marie Curie Universit\u00e9 Paris 06, Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale, Unit\u00e9 Mixte de 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