{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T20:20:47Z","timestamp":1770322847043,"version":"3.49.0"},"reference-count":19,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2018,3,1]],"date-time":"2018-03-01T00:00:00Z","timestamp":1519862400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,3,1]]},"DOI":"10.1513\/annalsats.201707-585cc","type":"journal-article","created":{"date-parts":[[2018,3,1]],"date-time":"2018-03-01T10:22:26Z","timestamp":1519899746000},"page":"380-382","source":"Crossref","is-referenced-by-count":0,"title":["A Woman with a 15-Year History of Bronchiectasis and Recurrent Nontuberculous\n                    <i>Mycobacterium<\/i>\n                    Pulmonary Disease"],"prefix":"10.1093","volume":"15","author":[{"given":"Patricia E.","family":"Hogan","sequence":"first","affiliation":[{"name":"Pulmonary Critical Care Fellowship, Naval Medical Center, San Diego, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tilman","family":"Koelsch","sequence":"additional","affiliation":[{"name":"Department of Radiology, and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles L.","family":"Daley","sequence":"additional","affiliation":[{"name":"Department of Medicine, National Jewish Health, Denver, Colorado; and"},{"name":"Department of Medicine, University of Colorado, Aurora, Colorado"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shannon H.","family":"Kasperbauer","sequence":"additional","affiliation":[{"name":"Department of Medicine, National Jewish Health, Denver, Colorado; and"},{"name":"Department of Medicine, University of Colorado, Aurora, Colorado"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2018,3,1]]},"reference":[{"key":"2026020502163944500_bib1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ccm.2014.10.001","article-title":"Pathogenesis and risk factors for nontuberculous mycobacterial lung disease","volume":"36","author":"Honda","year":"2015","journal-title":"Clin Chest Med"},{"key":"2026020502163944500_bib2","doi-asserted-by":"crossref","first-page":"507","DOI":"10.3949\/ccjm.83a.16031","article-title":"Alpha-1 antitrypsin deficiency: an underrecognized, treatable cause of COPD","volume":"83","author":"Stoller","year":"2016","journal-title":"Cleve Clin J Med"},{"key":"2026020502163944500_bib3","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1378\/chest.122.4.1247","article-title":"The relationship of chronic sputum expectoration to physiologic, radiologic, and health status characteristics in \u03b11-antitrypsin deficiency (PiZ)","volume":"122","author":"Dowson","year":"2002","journal-title":"Chest"},{"key":"2026020502163944500_bib4","doi-asserted-by":"crossref","first-page":"1384","DOI":"10.1378\/chest.104.5.1384","article-title":"Bronchiectasis in patients with \u03b11-antitrypsin deficiency: a rare occurrence?","volume":"104","author":"Shin","year":"1993","journal-title":"Chest"},{"key":"2026020502163944500_bib5","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1148\/radiology.199.1.8633137","article-title":"Alpha 1-antitrypsin deficiency: evaluation of bronchiectasis with CT","volume":"199","author":"King","year":"1996","journal-title":"Radiology"},{"key":"2026020502163944500_bib6","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1164\/rccm.200703-489OC","article-title":"Prevalence and impact of bronchiectasis in \u03b11-antitrypsin deficiency","volume":"176","author":"Parr","year":"2007","journal-title":"Am J Respir Crit Care Med"},{"key":"2026020502163944500_bib7","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.molmed.2013.11.006","article-title":"\u03b1-1-Antitrypsin deficiency: clinical variability, assessment, and treatment","volume":"20","author":"Stockley","year":"2014","journal-title":"Trends Mol Med"},{"key":"2026020502163944500_bib8","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.ccm.2013.10.001","article-title":"Alpha1-antitrypsin review","volume":"35","author":"Stockley","year":"2014","journal-title":"Clin Chest Med"},{"key":"2026020502163944500_bib9","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1164\/rccm.168.7.818","article-title":"American Thoracic Society\/European Respiratory Society statement: standards for the diagnosis and management of individuals with alpha-1 antitrypsin deficiency","volume":"168","author":"American Thoracic Society","year":"2003","journal-title":"Am J Respir Crit Care Med"},{"key":"2026020502163944500_bib10","doi-asserted-by":"crossref","first-page":"26","DOI":"10.3109\/15412555.2013.763782","article-title":"The challenge of detecting alpha-1 antitrypsin deficiency","volume":"10","author":"Stoller","year":"2013","journal-title":"COPD"},{"key":"2026020502163944500_bib11","doi-asserted-by":"crossref","first-page":"68","DOI":"10.3109\/15412555.2013.764404","article-title":"Airway disease in alpha-1 antitrypsin deficiency","volume":"10","author":"Strange","year":"2013","journal-title":"COPD"},{"key":"2026020502163944500_bib12","doi-asserted-by":"crossref","first-page":"64","DOI":"10.3109\/15412555.2013.764402","article-title":"Alpha-1 antitrypsin augmentation therapy","volume":"10","author":"Wewers","year":"2013","journal-title":"COPD"},{"key":"2026020502163944500_bib13","doi-asserted-by":"crossref","first-page":"S370","DOI":"10.1513\/AnnalsATS.201510-684KV","article-title":"Randomized, placebo-controlled trials in alpha-1 antitrypsin deficiency","volume":"13","author":"Sandhaus","year":"2016","journal-title":"Ann Am Thorac Soc"},{"key":"2026020502163944500_bib14","doi-asserted-by":"crossref","first-page":"1494","DOI":"10.1164\/rccm.2109013","article-title":"The effect of augmentation therapy on bronchial inflammation in \u03b11-antitrypsin deficiency","volume":"165","author":"Stockley","year":"2002","journal-title":"Am J Respir Crit Care Med"},{"key":"2026020502163944500_bib15","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1016\/S0140-6736(15)60860-1","article-title":"Intravenous augmentation treatment and lung density in severe \u03b11 antitrypsin deficiency (RAPID): a randomised, double-blind, placebo-controlled trial","volume":"386","author":"Chapman","year":"2015","journal-title":"Lancet"},{"key":"2026020502163944500_bib16","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/S2213-2600(16)30430-1","article-title":"Long-term efficacy and safety of \u03b11 proteinase inhibitor treatment for emphysema caused by severe \u03b11 antitrypsin deficiency: an open-label extension trial (RAPID-OLE)","volume":"5","author":"McElvaney","year":"2017","journal-title":"Lancet Respir Med"},{"key":"2026020502163944500_bib17","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1080\/00365540701225744","article-title":"Alpha-1-antitrypsin (AAT) anomalies are associated with lung disease due to rapidly growing mycobacteria and AAT inhibits Mycobacterium abscessus infection of macrophages","volume":"39","author":"Chan","year":"2007","journal-title":"Scand J Infect Dis"},{"key":"2026020502163944500_bib18","first-page":"A132","article-title":"Do mutations of the alpha-1-antitrypsin gene predispose to non-tuberculous mycobacterial infection? [abstract]","volume":"169","author":"Chan","year":"2004","journal-title":"Am J Respir Crit Care Med"},{"key":"2026020502163944500_bib19","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1378\/chest.08-0868","article-title":"\u03b11-Antitrypsin augmentation therapy for PI*MZ heterozygotes: a cautionary note","volume":"134","author":"Sandhaus","year":"2008","journal-title":"Chest"}],"container-title":["Annals of the American Thoracic Society"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/annalsats\/article-pdf\/15\/3\/380\/66733121\/annalsats_15_3_380.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/annalsats\/article-pdf\/15\/3\/380\/66733121\/annalsats_15_3_380.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T07:16:47Z","timestamp":1770275807000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/annalsats\/article\/15\/3\/380\/8456832"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,3,1]]},"references-count":19,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2018,3,1]]},"published-print":{"date-parts":[[2018,3,1]]}},"URL":"https:\/\/doi.org\/10.1513\/annalsats.201707-585cc","relation":{},"ISSN":["2329-6933","2325-6621"],"issn-type":[{"value":"2329-6933","type":"print"},{"value":"2325-6621","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2018,3]]},"published":{"date-parts":[[2018,3,1]]}}}