{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T17:16:12Z","timestamp":1790356572937,"version":"4.1.0"},"reference-count":80,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":["www.atsjournals.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,2,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Sarcoidosis is a multisystem disease characterized by noncaseating granulomatous inflammation that most commonly involves the lungs. Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) has become an invaluable tool in the assessment of patients with mediastinal and\/or hilar lymphadenopathy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>It has been hypothesized that use of the larger 19-gauge (G) needle with EBUS-TBNA improves diagnostic sensitivity in sarcoidosis. However, it is unclear whether the existing literature supports this supposition.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Data Sources<\/jats:title>\n                    <jats:p>A literature search of Embase and Medline was performed by two reviewers. Included articles were evaluated for bias using the QUADAS-2 tool.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Data Extraction<\/jats:title>\n                    <jats:p>For quantitative analysis, we performed a meta-analysis using a binary random-effects model to determine pooled sensitivity. Subgroup analysis was performed based on needle size, use of rapid on-site evaluation (ROSE), study design, and prevalence of sarcoidosis in study group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Synthesis<\/jats:title>\n                    <jats:p>Sixty-five studies with a total of 4,242 patients were included in the meta-analysis. Overall pooled sensitivity for diagnosis of sarcoidosis was 83.99% (95% confidence interval [CI], 81.22\u201386.53) among all studies. The 19G subgroup had a significantly higher sensitivity (93.73%; 95% CI, 89.72\u201397.74%; I \u00a02\u2009=\u20090.00%; P\u2009&amp;lt;\u20090.01) compared with the 21G subgroup (84.61%; 95% CI, 78.80\u201390.42%; I \u00a02\u2009=\u200969.83%), 22G subgroup (84.07%; 95% CI, 80.90\u201387.24%; I \u00a02\u2009=\u200985.21%) or unspecified 21G\/22G subgroup (78.85%; 95% CI, 70.81\u201386.90%; I \u00a02\u2009=\u200984.47%). There were no significant differences with use of ROSE or prevalence of sarcoidosis or by study design.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The use of 19G needles during EBUS-TBNA had the highest diagnostic sensitivity based on available studies. Further randomized controlled trials using 19G needles should be considered in patients with suspected sarcoidosis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1513\/annalsats.202103-366oc","type":"journal-article","created":{"date-parts":[[2021,8,19]],"date-time":"2021-08-19T15:22:32Z","timestamp":1629386552000},"page":"279-290","update-policy":"https:\/\/doi.org\/10.1164\/crossmarkpolicies","source":"Crossref","is-referenced-by-count":33,"title":["Effect of Needle Size on Diagnosis of Sarcoidosis with Endobronchial Ultrasound-guided Transbronchial Needle Aspiration: Systematic Review and Meta-Analysis"],"prefix":"10.1093","volume":"19","author":[{"given":"Shayan","family":"Kassirian","sequence":"first","affiliation":[{"name":"Division of Respirology, Department of Medicine, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie N.","family":"Hinton","sequence":"additional","affiliation":[{"name":"Division of Respirology, Department of Medicine, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alla","family":"Iansavitchene","sequence":"additional","affiliation":[{"name":"Library Services, London Health Sciences Centre, London, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kayvan","family":"Amjadi","sequence":"additional","affiliation":[{"name":"Division of Respirology, Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex","family":"Chee","sequence":"additional","affiliation":[{"name":"Division of Respirology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Inderdeep","family":"Dhaliwal","sequence":"additional","affiliation":[{"name":"Division of Respirology, Department of Medicine, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4163-837X","authenticated-orcid":false,"given":"Michael A.","family":"Mitchell","sequence":"additional","affiliation":[{"name":"Division of Respirology, Department of Medicine, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2022,2,1]]},"reference":[{"key":"2026012203302643900_bib1","doi-asserted-by":"crossref","first-page":"3300","DOI":"10.1001\/jama.289.24.3300","article-title":"Sarcoidosis","volume":"289","author":"Thomas","year":"2003","journal-title":"JAMA"},{"key":"2026012203302643900_bib2","doi-asserted-by":"crossref","first-page":"1156","DOI":"10.1183\/09031936.00097908","article-title":"Effectiveness and safety of endobronchial ultrasound-transbronchial needle aspiration: a systematic review","volume":"33","author":"Varela-Lema","year":"2009","journal-title":"Eur Respir J"},{"key":"2026012203302643900_bib3","doi-asserted-by":"crossref","first-page":"e26","DOI":"10.1164\/rccm.202002-0251ST","article-title":"Diagnosis and detection of sarcoidosis. an official American Thoracic Society clinical practice guideline","volume":"201","author":"Crouser","year":"2020","journal-title":"Am J Respir Crit Care Med"},{"key":"2026012203302643900_bib4","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.1378\/chest.07-0998","article-title":"Endobronchial ultrasound for the diagnosis of pulmonary sarcoidosis","volume":"132","author":"Garwood","year":"2007","journal-title":"Chest"},{"key":"2026012203302643900_bib5","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1164\/rccm.201203-0393OC","article-title":"Endobronchial ultrasound-guided transbronchial needle aspiration prevents mediastinoscopies in the diagnosis of isolated mediastinal lymphadenopathy: a prospective trial","volume":"186","author":"Navani","year":"2012","journal-title":"Am J Respir Crit Care Med"},{"key":"2026012203302643900_bib6","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1378\/chest.11-0692","article-title":"Randomized clinical trial of endobronchial ultrasound needle biopsy with and without aspiration","volume":"142","author":"Casal","year":"2012","journal-title":"Chest"},{"key":"2026012203302643900_bib7","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1016\/j.chest.2016.01.014","article-title":"A prospective, randomized, double-blind trial comparing the diagnostic yield of 21- and 22-gauge aspiration needles for performing endobronchial ultrasound-guided transbronchial needle aspiration in sarcoidosis","volume":"149","author":"Muthu","year":"2016","journal-title":"Chest"},{"key":"2026012203302643900_bib8","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1111\/j.1440-1843.2010.01871.x","article-title":"Comparison of 21-gauge and 22-gauge aspiration needle during endobronchial ultrasound-guided transbronchial needle aspiration","volume":"16","author":"Nakajima","year":"2011","journal-title":"Respirology"},{"key":"2026012203302643900_bib9","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1097\/LBR.0000000000000500","article-title":"Endobronchial ultrasound-guided transbronchial needle aspiration with a 19-G needle device","volume":"25","author":"Tremblay","year":"2018","journal-title":"J Bronchology Interv Pulmonol"},{"key":"2026012203302643900_bib10","article-title":"Pilot study of the performance of 19-G needle in endobronchial ultrasound-guided transbronchial aspiration for the diagnosis and testing of molecular markers in lung cancer","author":"Wahidi","year":"2020","journal-title":"J Bronchol Interv Pulmonol"},{"key":"2026012203302643900_bib11","doi-asserted-by":"crossref","first-page":"E864","DOI":"10.21037\/jtd.2017.08.46","article-title":"Comparison of the yield of 19-G eXcelon core needle to a 21-G EBUS needle during endobronchial ultrasound guided transbronchial needle aspiration of mediastinal lymph nodes for the detection of granulomas in cases of suspected sarcoidosis","volume":"9","author":"Biswas","year":"2017","journal-title":"J Thorac Dis"},{"key":"2026012203302643900_bib12","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1159\/000479745","article-title":"Performance of endobronchial ultrasound-guided transbronchial needle aspiration for the diagnosis of isolated mediastinal and hilar lymphadenopathy","volume":"94","author":"Tyan","year":"2017","journal-title":"Respiration"},{"key":"2026012203302643900_bib13","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1001\/jama.2017.19163","article-title":"Preferred Reporting Items for a Systematic Review and Meta-analysis of Diagnostic Test Accuracy Studies: the PRISMA-DTA statement","volume":"319","author":"McInnes","year":"2018","journal-title":"JAMA"},{"key":"2026012203302643900_bib14","doi-asserted-by":"crossref","first-page":"529","DOI":"10.7326\/0003-4819-155-8-201110180-00009","article-title":"QUADAS-2: a revised tool for the quality assessment of diagnostic accuracy studies","volume":"155","author":"Whiting","year":"2011","journal-title":"Ann Intern Med"},{"key":"2026012203302643900_bib15","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1186\/s12890-019-0909-4","article-title":"A pragmatic application of endobronchial ultrasound-guided transbronchial needle aspiration: a single institution experience","volume":"19","author":"Bailey","year":"2019","journal-title":"BMC Pulm Med"},{"key":"2026012203302643900_bib16","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1097\/LBR.0000000000000502","article-title":"Endobronchial ultrasound-guided transbronchial needle aspiration using 19-G needle for sarcoidosis","volume":"25","author":"Balwan","year":"2018","journal-title":"J Bronchology Interv Pulmonol"},{"key":"2026012203302643900_bib17","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/j.rmr.2017.01.011","article-title":"Endobronchial ultrasound with transbronchial needle aspiration: Evaluation of clinical practice [in French]","volume":"35","author":"Basille","year":"2018","journal-title":"Rev Mal Respir"},{"key":"2026012203302643900_bib18","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1097\/LBR.0b013e3182442b89","article-title":"Endobronchial ultrasound with transbronchial needle aspiration in the diagnosis of bilateral hilar and mediastinal lymphadenopathy","volume":"19","author":"Boujaoude","year":"2012","journal-title":"J Bronchology Interv Pulmonol"},{"key":"2026012203302643900_bib19","doi-asserted-by":"crossref","first-page":"1683","DOI":"10.7863\/jum.2011.30.12.1683","article-title":"Sensitivity of convex probe endobronchial sonographically guided transbronchial needle aspiration in the diagnosis of granulomatous mediastinal lymphadenitis","volume":"30","author":"\u00c7a\u011flayan","year":"2011","journal-title":"J Ultrasound Med"},{"key":"2026012203302643900_bib20","doi-asserted-by":"crossref","first-page":"77","DOI":"10.4103\/1817-1737.78422","article-title":"Value of real-time endobronchial ultrasound-guided transbronchial needle aspiration","volume":"6","author":"Cetinkaya","year":"2011","journal-title":"Ann Thorac Med"},{"key":"2026012203302643900_bib21","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1097\/LBR.0b013e3182442925","article-title":"Cytologic assessment of endobronchial ultrasound-guided transbronchial needle aspirates in sarcoidosis","volume":"19","author":"Chee","year":"2012","journal-title":"J Bronchology Interv Pulmonol"},{"key":"2026012203302643900_bib22","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1159\/000490192","article-title":"A randomized trial evaluating the effect of 10 versus 20 revolutions inside the lymph node on the diagnostic yield of EBUS-TBNA in subjects with sarcoidosis","volume":"96","author":"Dhooria","year":"2018","journal-title":"Respiration"},{"key":"2026012203302643900_bib23","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1111\/crj.12304","article-title":"The role of EBUS-TBNA and standard bronchoscopic modalities in the diagnosis of sarcoidosis","volume":"11","author":"Dziedzic","year":"2017","journal-title":"Clin Respir J"},{"key":"2026012203302643900_bib24","first-page":"43","article-title":"Minimally invasive diagnosis of sarcoidosis by EBUS when conventional diagnostics fail","volume":"27","author":"Eckardt","year":"2010","journal-title":"Sarcoidosis Vasc Diffuse Lung Dis"},{"key":"2026012203302643900_bib25","doi-asserted-by":"crossref","first-page":"e000040","DOI":"10.1136\/bmjresp-2014-000040","article-title":"A study of patients with isolated mediastinal and hilar lymphadenopathy undergoing EBUS-TBNA","volume":"1","author":"Evison","year":"2014","journal-title":"BMJ Open Respir Res"},{"key":"2026012203302643900_bib26","first-page":"582","article-title":"Usefulness of combined endobronchial and endoscopic ultrasound-guided needle aspiration in the diagnosis of sarcoidosis: a prospective multicenter trial","volume":"130","author":"Filarecka","year":"2020","journal-title":"Pol Arch Intern Med"},{"key":"2026012203302643900_bib27","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1097\/LBR.0b013e31828f4617","article-title":"Endobronchial ultrasound-guided transbronchial needle aspiration in an unselected cohort","volume":"20","author":"Gindesgaard","year":"2013","journal-title":"J Bronchology Interv Pulmonol"},{"key":"2026012203302643900_bib28","doi-asserted-by":"crossref","first-page":"321","DOI":"10.20452\/pamw.2828","article-title":"Comparison of conventional and ultrasound-guided needle biopsy techniques in the diagnosis of sarcoidosis: a randomized trial","volume":"125","author":"Gnass","year":"2015","journal-title":"Pol Arch Med Wewn"},{"key":"2026012203302643900_bib29","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1097\/LBR.0000000000000081","article-title":"Value of different bronchoscopic sampling techniques in diagnosis of sarcoidosis: a prospective study of 151 patients","volume":"21","author":"Goyal","year":"2014","journal-title":"J Bronchology Interv Pulmonol"},{"key":"2026012203302643900_bib30","first-page":"5393","article-title":"Evaluation of mediastinal lymph nodes with endobronchial ultrasoundguided transbronchial needle aspiration (EBUS-TBNA): A retrospective study","volume":"28","author":"Gungen","year":"2017","journal-title":"Biomed Res (Aligarh)"},{"key":"2026012203302643900_bib31","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1378\/chest.13-2339","article-title":"Endobronchial ultrasound-guided transbronchial needle aspiration vs conventional transbronchial needle aspiration in the diagnosis of sarcoidosis","volume":"146","author":"Gupta","year":"2014","journal-title":"Chest"},{"key":"2026012203302643900_bib32","doi-asserted-by":"crossref","first-page":"128","DOI":"10.4103\/JOC.JOC_150_18","article-title":"Role of EBUS-TBNA in the diagnosis of tuberculosis and sarcoidosis","volume":"36","author":"Gupta","year":"2019","journal-title":"J Cytol"},{"key":"2026012203302643900_bib33","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1111\/j.1752-699X.2010.00232.x","article-title":"EBUS-TBNA in mediastinal\/hilar lymphadenopathies and\/or masses: an Italian case series","volume":"6","author":"Gurioli","year":"2012","journal-title":"Clin Respir J"},{"key":"2026012203302643900_bib34","first-page":"1737","article-title":"Value of EBUS-TBNA cytopathological detection in diagnosis of lung cancer and sarcoidosis","volume":"31","author":"Han","year":"2011","journal-title":"J Shanghai Jiaotong Univ Med Sci"},{"key":"2026012203302643900_bib35","doi-asserted-by":"crossref","first-page":"1416","DOI":"10.3349\/ymj.2013.54.6.1416","article-title":"Usefulness of endobronchial ultrasound-guided transbronchial needle aspiration for diagnosis of sarcoidosis","volume":"54","author":"Hong","year":"2013","journal-title":"Yonsei Med J"},{"key":"2026012203302643900_bib36","doi-asserted-by":"crossref","first-page":"S350","DOI":"10.21037\/jtd.2017.05.18","article-title":"Understanding local performance data for EBUS-TBNA: insights from an unselected case series at a high volume UK center","volume":"9","author":"Jeebun","year":"2017","journal-title":"J Thorac Dis"},{"key":"2026012203302643900_bib37","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1111\/j.1752-699X.2011.00251.x","article-title":"Diagnostic yield and efficacy of endobronchial ultrasound-guided transbronchial needle aspiration in mediastinal lymphadenopathy","volume":"6","author":"Jernl\u00e5s","year":"2012","journal-title":"Clin Respir J"},{"key":"2026012203302643900_bib38","doi-asserted-by":"crossref","first-page":"915","DOI":"10.4081\/monaldi.2018.915","article-title":"The effect of 19-gauge endobronchial ultrasound-guided transbronchial needle aspiration biopsies on characterisation of malignant and benign disease. The Bristol experience","volume":"88","author":"Jones","year":"2018","journal-title":"Monaldi Arch Chest Dis"},{"key":"2026012203302643900_bib39","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1111\/crj.13285","article-title":"Combination of endosonography-guided fine-needle aspiration and conventional endoscopic techniques in sarcoidosis diagnosis. Optimal strategy to achieve high diagnostic yield","volume":"15","author":"Kasper","year":"2021","journal-title":"Clin Respir J"},{"key":"2026012203302643900_bib40","first-page":"310","article-title":"Endobronchial ultrasound guided transbronchial needle aspiration of mediastinal and hilar lymph nodes- five years of experience at a cancer setting hospital in Pakistan","volume":"32","author":"Khalid","year":"2020","journal-title":"J Ayub Med Coll Abbottabad"},{"key":"2026012203302643900_bib41","doi-asserted-by":"crossref","first-page":"267","DOI":"10.4046\/trd.2010.68.5.267","article-title":"Pulmonary sarcoidosis diagnosed by endobronchial ultrasound fine needle aspiration","volume":"68","author":"Kim","year":"2010","journal-title":"Tuberc Respir Dis (Seoul)"},{"key":"2026012203302643900_bib42","first-page":"154","article-title":"Endosonography-guided fine-needle aspiration in the diagnosis of sarcoidosis: a randomized study","volume":"127","author":"Koco\u0144","year":"2017","journal-title":"Pol Arch Intern Med"},{"key":"2026012203302643900_bib43","doi-asserted-by":"crossref","first-page":"2175","DOI":"10.21037\/jtd.2019.01.94","article-title":"Age is an independent predictor in pathological diagnosis of sarcoidosis: a retrospective analysis of diagnosis by endobronchial ultrasound-guided transbronchial needle aspiration","volume":"11","author":"Kuwasaki","year":"2019","journal-title":"J Thorac Dis"},{"key":"2026012203302643900_bib44","first-page":"211","article-title":"A randomized controlled study of conventional TBNA versus EBUS-TBNA for diagnosis of suspected stage I and II sarcoidosis","volume":"31","author":"Li","year":"2014","journal-title":"Sarcoidosis Vasc Diffuse Lung Dis"},{"key":"2026012203302643900_bib45","doi-asserted-by":"crossref","first-page":"250","DOI":"10.47102\/annals-acadmedsg.V43N5p250","article-title":"Use of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in the diagnosis of granulomatous mediastinal lymphadenopathy","volume":"43","author":"Low","year":"2014","journal-title":"Ann Acad Med Singap"},{"key":"2026012203302643900_bib46","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1097\/LBR.0000000000000080","article-title":"Initial experience with endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) from a tuberculosis endemic population","volume":"21","author":"Madan","year":"2014","journal-title":"J Bronchology Interv Pulmonol"},{"key":"2026012203302643900_bib47","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1097\/LBR.0000000000000339","article-title":"Conventional transbronchial needle aspiration versus endobronchial ultrasound-guided transbronchial needle aspiration, with or without rapid on-site evaluation, for the diagnosis of sarcoidosis: a randomized controlled trial","volume":"24","author":"Madan","year":"2017","journal-title":"J Bronchology Interv Pulmonol"},{"key":"2026012203302643900_bib48","first-page":"209","article-title":"Role of cytomorphology in differentiating sarcoidosis and tuberculosis in subjects undergoing endobronchial ultrasound-guided transbronchial needle aspiration","volume":"36","author":"Muthu","year":"2019","journal-title":"Sarcoidosis Vasc Diffuse Lung Dis"},{"key":"2026012203302643900_bib49","doi-asserted-by":"crossref","first-page":"1796","DOI":"10.1016\/j.rmed.2009.07.013","article-title":"The role of EBUS-TBNA for the diagnosis of sarcoidosis--comparisons with other bronchoscopic diagnostic modalities","volume":"103","author":"Nakajima","year":"2009","journal-title":"Respir Med"},{"key":"2026012203302643900_bib50","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1111\/j.1440-1843.2011.01933.x","article-title":"Combination of endobronchial ultrasound-guided transbronchial needle aspiration with standard bronchoscopic techniques for the diagnosis of stage I and stage II pulmonary sarcoidosis","volume":"16","author":"Navani","year":"2011","journal-title":"Respirology"},{"key":"2026012203302643900_bib51","doi-asserted-by":"crossref","first-page":"e000144","DOI":"10.1136\/bmjresp-2016-000144","article-title":"Yield of EBUS-TBNA for the diagnosis of sarcoidosis: impact of operator and cytopathologist experience","volume":"3","author":"Navasakulpong","year":"2016","journal-title":"BMJ Open Respir Res"},{"key":"2026012203302643900_bib52","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.resinv.2013.12.003","article-title":"Relationship between the ratios of CD4\/CD8 T-lymphocytes in the bronchoalveolar lavage fluid and lymph nodes in patients with sarcoidosis","volume":"52","author":"Oda","year":"2014","journal-title":"Respir Investig"},{"key":"2026012203302643900_bib53","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1111\/j.1440-1843.2007.01145.x","article-title":"Real-time endobronchial ultrasound-guided transbronchial needle aspiration is useful for diagnosing sarcoidosis","volume":"12","author":"Oki","year":"2007","journal-title":"Respirology"},{"key":"2026012203302643900_bib54","doi-asserted-by":"crossref","first-page":"1324","DOI":"10.1016\/j.jtcvs.2012.01.040","article-title":"Prospective study of endobronchial ultrasound-guided transbronchial needle aspiration of lymph nodes versus transbronchial lung biopsy of lung tissue for diagnosis of sarcoidosis","volume":"143","author":"Oki","year":"2012","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2026012203302643900_bib55","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1159\/000485661","article-title":"How many passes are needed for endobronchial ultrasound-guided transbronchial needle aspiration for sarcoidosis? A prospective multicenter study","volume":"95","author":"Oki","year":"2018","journal-title":"Respiration"},{"key":"2026012203302643900_bib56","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1590\/S1806-37132015000004493","article-title":"Diagnostic value of endobronchial ultrasound-guided transbronchial needle aspiration in various lung diseases","volume":"41","author":"Ortakoylu","year":"2015","journal-title":"J Bras Pneumol"},{"key":"2026012203302643900_bib57","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1111\/j.1445-5994.2011.02446.x","article-title":"Diagnostic utility of endobronchial ultrasound-guided transbronchial needle aspiration compared with transbronchial and endobronchial biopsy for suspected sarcoidosis","volume":"42","author":"Plit","year":"2012","journal-title":"Intern Med J"},{"key":"2026012203302643900_bib58","doi-asserted-by":"crossref","first-page":"1302","DOI":"10.1183\/09031936.00128312","article-title":"Rapid cytological analysis of endobronchial ultrasound-guided aspirates in sarcoidosis","volume":"42","author":"Plit","year":"2013","journal-title":"Eur Respir J"},{"key":"2026012203302643900_bib59","doi-asserted-by":"crossref","first-page":"31","DOI":"10.4103\/1742-6413.146118","article-title":"Utility of endoscopic ultrasound-guided transbronchial fine-needle cytology in the diagnosis of sarcoidosis: A Saudi experience","volume":"11","author":"Raddaoui","year":"2014","journal-title":"Cytojournal"},{"key":"2026012203302643900_bib60","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1016\/j.athoracsur.2019.08.106","article-title":"Improved diagnostic yield and specimen quality with endobronchial ultrasound-guided forceps biopsies: a retrospective analysis","volume":"109","author":"Ray","year":"2020","journal-title":"Ann Thorac Surg"},{"key":"2026012203302643900_bib61","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.rppneu.2014.02.005","article-title":"Diagnosis of sarcoidosis in the endobronchial ultrasound-guided transbronchial needle aspiration era","volume":"20","author":"Ribeiro","year":"2014","journal-title":"Rev Port Pneumol"},{"key":"2026012203302643900_bib62","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/j.athoracsur.2014.09.029","article-title":"Determining factors in diagnosing pulmonary sarcoidosis by endobronchial ultrasound-guided transbronchial needle aspiration","volume":"99","author":"Sun","year":"2015","journal-title":"Ann Thorac Surg"},{"key":"2026012203302643900_bib63","first-page":"2211","article-title":"Endobronchial ultrasound-guided transbronchial needle aspiration of undiagnosed mediastinal lymphadenopathy","volume":"123","author":"Tian","year":"2010","journal-title":"Chin Med J (Engl)"},{"key":"2026012203302643900_bib64","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1183\/09031936.00111509","article-title":"The value of endoscopic ultrasound after bronchoscopy to diagnose thoracic sarcoidosis","volume":"35","author":"Tournoy","year":"2010","journal-title":"Eur Respir J"},{"key":"2026012203302643900_bib65","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1378\/chest.08-2768","article-title":"A randomized controlled trial of standard vs endobronchial ultrasonography-guided transbronchial needle aspiration in patients with suspected sarcoidosis","volume":"136","author":"Tremblay","year":"2009","journal-title":"Chest"},{"key":"2026012203302643900_bib66","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1159\/000475504","article-title":"Flexible 19-gauge endobronchial ultrasound-guided transbronchial needle aspiration needle: first experience","volume":"94","author":"Tyan","year":"2017","journal-title":"Respiration"},{"key":"2026012203302643900_bib67","doi-asserted-by":"crossref","first-page":"2457","DOI":"10.1001\/jama.2013.5823","article-title":"Endosonography vs conventional bronchoscopy for the diagnosis of sarcoidosis: the GRANULOMA randomized clinical trial","volume":"309","author":"von Bartheld","year":"2013","journal-title":"JAMA"},{"key":"2026012203302643900_bib68","doi-asserted-by":"crossref","first-page":"2785","DOI":"10.1016\/j.ultrasmedbio.2016.07.019","article-title":"Sonographic features of endobronchial ultrasound in differentiation of benign lymph nodes","volume":"42","author":"Wang","year":"2016","journal-title":"Ultrasound Med Biol"},{"key":"2026012203302643900_bib69","doi-asserted-by":"crossref","first-page":"1182","DOI":"10.1183\/09031936.00028706","article-title":"Endobronchial ultrasound: new insight for the diagnosis of sarcoidosis","volume":"29","author":"Wong","year":"2007","journal-title":"Eur Respir J"},{"key":"2026012203302643900_bib70","doi-asserted-by":"crossref","first-page":"20","DOI":"10.4103\/1742-6413.165947","article-title":"Utility of endobronchial ultrasound-guided-fine-needle aspiration and additional value of cell block in the diagnosis of mediastinal granulomatous lymphadenopathy","volume":"12","author":"Zaidi","year":"2015","journal-title":"Cytojournal"},{"key":"2026012203302643900_bib71","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1111\/crj.12317","article-title":"Endobronchial ultrasound-guided transbronchial needle aspiration for diagnosing mediastinal lymphadenectasis: a cohort study from a single center","volume":"11","author":"Zhu","year":"2017","journal-title":"Clin Respir J"},{"key":"2026012203302643900_bib72","first-page":"72","article-title":"Efficacy of endobronchial ultrasound-guided transbronchial needle aspiration in the diagnosis of thoracic sarcoidosis","volume":"66","author":"Zhao","year":"2017","journal-title":"West Indian Med J"},{"key":"2026012203302643900_bib73","doi-asserted-by":"crossref","first-page":"19","DOI":"10.3390\/medicina54020019","article-title":"Diagnostic yield of endobronchial ultrasound-guided transbronchial needle aspiration cytological smears and cell blocks: a single-institution experience","volume":"54","author":"\u017demaitis","year":"2018","journal-title":"Medicina (Kaunas)"},{"key":"2026012203302643900_bib74","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1186\/1465-9921-14-50","article-title":"Complications associated with endobronchial ultrasound-guided transbronchial needle aspiration: a nationwide survey by the Japan Society for Respiratory Endoscopy","volume":"14","author":"Asano","year":"2013","journal-title":"Respir Res"},{"key":"2026012203302643900_bib75","doi-asserted-by":"crossref","first-page":"1874","DOI":"10.1016\/j.athoracsur.2008.02.031","article-title":"Endobronchial ultrasound-guided miniforceps biopsy in the biopsy of subcarinal masses in patients with low likelihood of non-small cell lung cancer","volume":"85","author":"Herth","year":"2008","journal-title":"Ann Thorac Surg"},{"key":"2026012203302643900_bib76","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1136\/thoraxjnl-2019-214348","article-title":"BTS Clinical Statement on pulmonary sarcoidosis","volume":"76","author":"Thillai","year":"2021","journal-title":"Thorax"},{"key":"2026012203302643900_bib77","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1016\/j.rmed.2012.02.014","article-title":"Efficacy and safety of convex probe EBUS-TBNA in sarcoidosis: a systematic review and meta-analysis","volume":"106","author":"Agarwal","year":"2012","journal-title":"Respir Med"},{"key":"2026012203302643900_bib78","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1159\/000489473","article-title":"A randomized clinical trial of flex 19G needles versus 22G needles for endobronchial ultrasonography in suspected lung cancer","volume":"96","author":"Dooms","year":"2018","journal-title":"Respiration"},{"key":"2026012203302643900_bib79","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1097\/LBR.0000000000000515","article-title":"Comparison of sample adequacy and diagnostic yield of 19- and 22-G EBUS-TBNA needles","volume":"25","author":"Chaddha","year":"2018","journal-title":"J Bronchology Interv Pulmonol"},{"key":"2026012203302643900_bib80","doi-asserted-by":"crossref","first-page":"1432","DOI":"10.1513\/AnnalsATS.201902-175OC","article-title":"Diagnostic accuracy of endobronchial ultrasound transbronchial needle aspiration in lymphoma. A systematic review and meta-analysis","volume":"16","author":"Labarca","year":"2019","journal-title":"Ann Am Thorac Soc"}],"container-title":["Annals of the American Thoracic Society"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/annalsats\/article-pdf\/19\/2\/279\/66332803\/annalsats_19_2_279.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/annalsats\/article-pdf\/19\/2\/279\/66332803\/annalsats_19_2_279.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T08:32:39Z","timestamp":1769070759000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/annalsats\/article\/19\/2\/279\/8419067"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2,1]]},"references-count":80,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2022,2,1]]},"published-print":{"date-parts":[[2022,2,1]]}},"URL":"https:\/\/doi.org\/10.1513\/annalsats.202103-366oc","relation":{},"ISSN":["2329-6933","2325-6621"],"issn-type":[{"value":"2329-6933","type":"print"},{"value":"2325-6621","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2022,2]]},"published":{"date-parts":[[2022,2,1]]},"assertion":[{"value":"2021-03-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-08-18","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-02-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}