{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T12:40:39Z","timestamp":1791549639670,"version":"4.3.4"},"reference-count":27,"publisher":"Oxford University Press (OUP)","issue":"11","license":[{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["3U01HL123018-06S1"],"award-info":[{"award-number":["3U01HL123018-06S1"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008173","name":"Intermountain Research and Medical Foundation","doi-asserted-by":"publisher","award":["AWD01126"],"award-info":[{"award-number":["AWD01126"]}],"id":[{"id":"10.13039\/100008173","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["3U01HL123018-06S1"],"award-info":[{"award-number":["3U01HL123018-06S1"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008173","name":"Intermountain Research and Medical Foundation","doi-asserted-by":"crossref","award":["AWD01126"],"award-info":[{"award-number":["AWD01126"]}],"id":[{"id":"10.13039\/100008173","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["www.atsjournals.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,11,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Rationale<\/jats:title>\n                    <jats:p>E-cigarette\u2013 or vaping-associated lung injury (EVALI) was first identified in 2019. The long-term respiratory, cognitive, mood disorder, and vaping behavior outcomes of patients with EVALI remain unknown.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To determine the long-term respiratory, cognitive, mood disorder, and vaping behavior outcomes of patients with EVALI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We prospectively enrolled patients with EVALI from two health systems. We assessed outcomes at 1 year after onset of EVALI using validated instruments measuring cognitive function, depression, anxiety, post-traumatic stress, respiratory disability, coronavirus disease (COVID-19) infection, pulmonary function, and vaping behaviors. We used multivariable regression to identify risk factors of post-EVALI vaping behaviors and to identify whether admission to the intensive care unit (ICU) was associated with cognitive, respiratory, or mood symptoms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Seventy-three patients completed 12-month follow-up. Most patients were male (66.7%), young (mean age, 31\u2009\u00b1\u200911 yr), and White (85%) and did not need admission to the ICU (59%). At 12 months, 39% (25 of 64) had cognitive impairment, whereas 48% (30 of 62) reported respiratory limitations. Mood disorders were common, with 59% (38 of 64) reporting anxiety and\/or depression and 62% (39 of 63) having post-traumatic stress. Four (6.4%) of 64 reported a history of COVID-19 infection. Despite the history of EVALI, many people continued to vape. Only 38% (24 of 64) reported quitting all vaping and smoking behaviors. Younger age was associated with reduced vaping behavior after EVALI (odds ratio, 0.93; P\u2009=\u20090.02). ICU admission was not associated with cognitive impairment, dyspnea, or mood symptoms.<\/jats:p>\n                    <jats:p>Conclusions: Patients with EVALI, despite their youth, commonly have significant long-term respiratory disability; cognitive impairment; symptoms of depression, anxiety, post-traumatic stress; and persistent vaping.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1513\/annalsats.202201-049oc","type":"journal-article","created":{"date-parts":[[2022,5,9]],"date-time":"2022-05-09T15:32:37Z","timestamp":1652110357000},"page":"1892-1899","update-policy":"https:\/\/doi.org\/10.1164\/crossmarkpolicies","source":"Crossref","is-referenced-by-count":20,"title":["Prospectively Assessed Long-Term Outcomes of Patients with E-Cigarette\u2013 or Vaping-associated Lung Injury"],"prefix":"10.1093","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0860-1153","authenticated-orcid":false,"given":"Denitza P.","family":"Blagev","sequence":"first","affiliation":[{"name":"Pulmonary and Critical Care Medicine Division, Department of Medicine"},{"name":"Division of Pulmonary & Critical Care Medicine, Department of Medicine, University of Utah, Salt Lake City, Utah; and"},{"name":"Department of Research"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2182-7704","authenticated-orcid":false,"given":"Sean J.","family":"Callahan","sequence":"additional","affiliation":[{"name":"Division of Pulmonary & Critical Care Medicine, Department of Medicine, University of Utah, Salt Lake City, Utah; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dixie","family":"Harris","sequence":"additional","affiliation":[{"name":"Pulmonary and Critical Care Medicine Division, Department of Medicine"},{"name":"Telecritical Care Division, Department of Intermountain Telehealth, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dave S.","family":"Collingridge","sequence":"additional","affiliation":[{"name":"Department of Research"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramona O.","family":"Hopkins","sequence":"additional","affiliation":[{"name":"Neuroscience Center, Department of Psychology, Brigham Young University, Provo, Utah"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacqueline R.","family":"Eve","sequence":"additional","affiliation":[{"name":"Enterprise Analytics, Intermountain Healthcare, Salt Lake City, Utah"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lindsey","family":"Waddoups","sequence":"additional","affiliation":[{"name":"Division of Pulmonary & Critical Care Medicine, Department of Medicine, University of Utah, Salt Lake City, Utah; 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