{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T01:06:09Z","timestamp":1769130369964,"version":"3.49.0"},"reference-count":13,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T00:00:00Z","timestamp":1769040000000},"content-version":"vor","delay-in-days":1027,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000050","name":"NHLBI","doi-asserted-by":"publisher","award":["P01 HL158507"],"award-info":[{"award-number":["P01 HL158507"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"NHLBI","doi-asserted-by":"publisher","award":["T32HL091816"],"award-info":[{"award-number":["T32HL091816"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"NHLBI","doi-asserted-by":"crossref","award":["P01 HL158507"],"award-info":[{"award-number":["P01 HL158507"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000050","name":"NHLBI","doi-asserted-by":"crossref","award":["T32HL091816"],"award-info":[{"award-number":["T32HL091816"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["www.atsjournals.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,4,1]]},"DOI":"10.1513\/annalsats.202301-021ed","type":"journal-article","created":{"date-parts":[[2023,3,31]],"date-time":"2023-03-31T10:39:36Z","timestamp":1680259176000},"page":"514-515","update-policy":"https:\/\/doi.org\/10.1164\/crossmarkpolicies","source":"Crossref","is-referenced-by-count":1,"title":["Mucus Plugging in Primary Ciliary Dyskinesia"],"prefix":"10.1093","volume":"20","author":[{"given":"Stephanie","family":"Adaikalam","sequence":"first","affiliation":[{"name":"Riley Hospital for Children and the Herman B. Wells Center for Pediatric Research, Indianapolis, Indiana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benjamin","family":"Gaston","sequence":"additional","affiliation":[{"name":"Riley Hospital for Children and the Herman B. Wells Center for Pediatric Research, Indianapolis, Indiana"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2023,4,1]]},"reference":[{"key":"2026012203263661500_bib1","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1002\/ppul.23304","article-title":"Diagnosis, monitoring, and treatment of primary ciliary dyskinesia: PCD foundation consensus recommendations based on state of the art review","volume":"51","author":"Shapiro","year":"2016","journal-title":"Pediatr Pulmonol"},{"key":"2026012203263661500_bib2","doi-asserted-by":"crossref","first-page":"e24","DOI":"10.1164\/rccm.201805-0819ST","article-title":"Diagnosis of primary ciliary dyskinesia: an official American Thoracic Society clinical practice guideline","volume":"197","author":"Shapiro","year":"2018","journal-title":"Am J Respir Crit Care Med"},{"key":"2026012203263661500_bib3","doi-asserted-by":"crossref","first-page":"1901066","DOI":"10.1183\/13993003.01066-2019","article-title":"ERS and ATS diagnostic guidelines for primary ciliary dyskinesia: similarities and differences in approach to diagnosis","volume":"54","author":"Shoemark","year":"2019","journal-title":"Eur Respir J"},{"key":"2026012203263661500_bib4","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1016\/S2213-2600(21)00453-7","article-title":"The global prevalence and ethnic heterogeneity of primary ciliary dyskinesia gene variants: a genetic database analysis","volume":"10","author":"Hannah","year":"2022","journal-title":"Lancet Respir Med"},{"key":"2026012203263661500_bib5","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/S2213-2600(19)30374-1","article-title":"Primary ciliary dyskinesia in the genomics age","volume":"8","author":"Lucas","year":"2020","journal-title":"Lancet Respir Med"},{"key":"2026012203263661500_bib6","doi-asserted-by":"crossref","first-page":"2004601","DOI":"10.1183\/13993003.04601-2020","article-title":"The BEAT-PCD (Better Experimental Approaches to Treat Primary Ciliary Dyskinesia) clinical research collaboration","volume":"57","author":"Goutaki","year":"2021","journal-title":"Eur Respir J"},{"key":"2026012203263661500_bib7","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1513\/AnnalsATS.202206-524OC","article-title":"Airway disease in children with primary ciliary dyskinesia: impact of ciliary ultrastructure defect and genotype","volume":"20","author":"Kinghorn","year":"2023","journal-title":"Ann Am Thorac Soc"},{"key":"2026012203263661500_bib8","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1172\/JCI95693","article-title":"Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction","volume":"128","author":"Dunican","year":"2018","journal-title":"J Clin Invest"},{"key":"2026012203263661500_bib9","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1002\/ppul.24249","article-title":"CF derived scoring systems do not fully describe the range of structural changes seen on CT scans in PCD","volume":"54","author":"Tadd","year":"2019","journal-title":"Pediatr Pulmonol"},{"key":"2026012203263661500_bib10","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.jpeds.2004.02.038","article-title":"High-resolution computed tomography in young patients with cystic fibrosis: distribution of abnormalities and correlation with pulmonary function tests","volume":"145","author":"Brody","year":"2004","journal-title":"J Pediatr"},{"key":"2026012203263661500_bib11","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1148\/radiology.179.3.2027992","article-title":"Cystic fibrosis: scoring system with thin-section CT","volume":"179","author":"Bhalla","year":"1991","journal-title":"Radiology"},{"key":"2026012203263661500_bib12","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1164\/rccm.201409-1672OC","article-title":"Clinical features of childhood primary ciliary dyskinesia by genotype and ultrastructural phenotype","volume":"191","author":"Davis","year":"2015","journal-title":"Am J Respir Crit Care Med"},{"key":"2026012203263661500_bib13","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1164\/rccm.201803-0548OC","article-title":"Primary ciliary dyskinesia: longitudinal study of lung disease by ultrastructure defect and genotype","volume":"199","author":"Davis","year":"2019","journal-title":"Am J Respir Crit Care Med"}],"container-title":["Annals of the American Thoracic Society"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/annalsats\/article-pdf\/20\/4\/514\/66270301\/annalsats_20_4_514.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/annalsats\/article-pdf\/20\/4\/514\/66270301\/annalsats_20_4_514.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T08:27:25Z","timestamp":1769070445000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/annalsats\/article\/20\/4\/514\/8414878"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4,1]]},"references-count":13,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2023,4,1]]},"published-print":{"date-parts":[[2023,4,1]]}},"URL":"https:\/\/doi.org\/10.1513\/annalsats.202301-021ed","relation":{},"ISSN":["2329-6933","2325-6621"],"issn-type":[{"value":"2329-6933","type":"print"},{"value":"2325-6621","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2023,4]]},"published":{"date-parts":[[2023,4,1]]},"assertion":[{"value":"2023-03-31","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}