{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T09:23:36Z","timestamp":1777454616206,"version":"3.51.4"},"reference-count":30,"publisher":"Walter de Gruyter GmbH","issue":"9","funder":[{"DOI":"10.13039\/501100002347","name":"Bundesministerium f\u00fcr Bildung und Forschung","doi-asserted-by":"publisher","award":["13GW0118C"],"award-info":[{"award-number":["13GW0118C"]}],"id":[{"id":"10.13039\/501100002347","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,9,25]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Left ventricular assist devices (LVADs) have become a viable alternative to heart transplantation in heart failure therapy. In clinical practice, rotary blood pumps used as LVADs are operated at a constant rotational speed and thus do not adapt to the varying demand of the patient. This paper presents a robust control approach for automatic adaptation of the blood pump speed to the blood flow demand of the patient\u2019s body, which enables a defined load sharing between an LVAD and the native ventricle. Robust stability was checked using a detailed model of the human cardiovascular system with uncertainties that describe the most important native physiological control loops as well as a range of pathologies. The robust assistance controller was tested in an <jats:italic>in vivo<\/jats:italic> setup and was able to stabilize the cardiovascular system after myocardial infarction.<\/jats:p>","DOI":"10.1515\/auto-2018-0014","type":"journal-article","created":{"date-parts":[[2018,9,13]],"date-time":"2018-09-13T09:00:43Z","timestamp":1536829243000},"page":"767-779","source":"Crossref","is-referenced-by-count":8,"title":["Robust physiological control of rotary blood pumps for heart failure therapy"],"prefix":"10.1515","volume":"66","author":[{"given":"Daniel","family":"R\u00fcschen","sequence":"first","affiliation":[{"name":"Philips Chair for Medical Information Technology, Helmholtz-Institute for Biomedical Engineering , RWTH Aachen University , Pauwelsstr. 20, 52074 Aachen , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sebastian","family":"Opitz","sequence":"additional","affiliation":[{"name":"Philips Chair for Medical Information Technology, Helmholtz-Institute for Biomedical Engineering , RWTH Aachen University , Pauwelsstr. 20, 52074 Aachen , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philip","family":"von Platen","sequence":"additional","affiliation":[{"name":"Philips Chair for Medical Information Technology, Helmholtz-Institute for Biomedical Engineering , RWTH Aachen University , Pauwelsstr. 20, 52074 Aachen , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leonie","family":"Korn","sequence":"additional","affiliation":[{"name":"Philips Chair for Medical Information Technology, Helmholtz-Institute for Biomedical Engineering , RWTH Aachen University , Pauwelsstr. 20, 52074 Aachen , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steffen","family":"Leonhardt","sequence":"additional","affiliation":[{"name":"Philips Chair for Medical Information Technology, Helmholtz-Institute for Biomedical Engineering , RWTH Aachen University , Pauwelsstr. 20, 52074 Aachen , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marian","family":"Walter","sequence":"additional","affiliation":[{"name":"Philips Chair for Medical Information Technology, Helmholtz-Institute for Biomedical Engineering , RWTH Aachen University , Pauwelsstr. 20, 52074 Aachen , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","published-online":{"date-parts":[[2018,9,13]]},"reference":[{"key":"2023033110031729317_j_auto-2018-0014_ref_001_w2aab3b7ab1b6b1ab1b5b1Aa","doi-asserted-by":"crossref","unstructured":"M. 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