{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,6,24]],"date-time":"2024-06-24T10:43:07Z","timestamp":1719225787318},"reference-count":0,"publisher":"Index Copernicus","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bio-Algorithms and Med-Systems"],"published-print":{"date-parts":[[2013,9,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>This article describes the role of protein fragments encoded by individual exons. Structural analysis of the hydrophobic core on the basis of the \u201cfuzzy oil drop\u201d model \u2013 in whole molecules as well as in fragments encoded by specific exons \u2013 indicates that, in each protein, at least one exon encodes a fragment, which is consistent with the theoretical distribution of hydrophobicity density. Quantitative assessment of the properties of such exons in selected proteins enables the model to be applied in identifying the structural (stabilizing) role of polypeptide chains encoded by individual exons. This is viewed as a preliminary step toward future exploitation of this technique in studying the alternative splicing phenomenon.<\/jats:p>","DOI":"10.1515\/bams-2013-0020","type":"journal-article","created":{"date-parts":[[2013,9,6]],"date-time":"2013-09-06T20:08:05Z","timestamp":1378498085000},"page":"103-114","source":"Crossref","is-referenced-by-count":1,"title":["Structural role of exon-coded fragments in proteins"],"prefix":"10.5604","volume":"9","author":[{"given":"Monika","family":"Piwowar","sequence":"first","affiliation":[{"name":"Department of Bioinformatics and Telemedicine, Medical College, Jagiellonian University, Krak\u00f3w, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mateusz","family":"Banach","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leszek","family":"Konieczny","sequence":"additional","affiliation":[{"name":"Chair of Medical Biochemistry, Medical College, Jagiellonian University, Krak\u00f3w, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irena","family":"Roterman","sequence":"additional","affiliation":[{"name":"Department of Bioinformatics and Telemedicine, Medical College, Jagiellonian University, Krak\u00f3w, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3689","published-online":{"date-parts":[[2013,9,6]]},"container-title":["bams"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.degruyter.com\/document\/doi\/10.1515\/bams-2013-0020\/xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.degruyter.com\/document\/doi\/10.1515\/bams-2013-0020\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,24]],"date-time":"2024-06-24T10:09:09Z","timestamp":1719223749000},"score":1,"resource":{"primary":{"URL":"https:\/\/bamsjournal.com\/resources\/html\/article\/details?id=617546"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,9,1]]},"references-count":0,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2013,9,6]]},"published-print":{"date-parts":[[2013,9,1]]}},"alternative-id":["10.1515\/bams-2013-0020"],"URL":"https:\/\/doi.org\/10.1515\/bams-2013-0020","relation":{},"ISSN":["1896-530X","1895-9091"],"issn-type":[{"value":"1896-530X","type":"electronic"},{"value":"1895-9091","type":"print"}],"subject":[],"published":{"date-parts":[[2013,9,1]]}}}