{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,4,5]],"date-time":"2023-04-05T00:53:52Z","timestamp":1680656032044},"reference-count":74,"publisher":"Walter de Gruyter GmbH","issue":"2","license":[{"start":{"date-parts":[[2017,7,5]],"date-time":"2017-07-05T00:00:00Z","timestamp":1499212800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,7,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Distinct bacteria are able to cope with highly diverse lifestyles; for instance, they can be free living or host-associated. Thus, these organisms must possess a large and varied genomic arsenal to withstand different environmental conditions. To facilitate the identification of genomic features that might influence bacterial adaptation to a specific niche, we introduce LifeStyle-Specific-Islands (LiSSI). LiSSI combines evolutionary sequence analysis with statistical learning (Random Forest with feature selection, model tuning and robustness analysis). In summary, our strategy aims to identify conserved consecutive homology sequences (islands) in genomes and to identify the most discriminant islands for each lifestyle.<\/jats:p>","DOI":"10.1515\/jib-2017-0010","type":"journal-article","created":{"date-parts":[[2017,7,5]],"date-time":"2017-07-05T10:00:57Z","timestamp":1499248857000},"source":"Crossref","is-referenced-by-count":1,"title":["LifeStyle-Specific-Islands (LiSSI): Integrated Bioinformatics Platform for Genomic Island Analysis"],"prefix":"10.1515","volume":"14","author":[{"given":"Eudes","family":"Barbosa","sequence":"first","affiliation":[{"name":"University of Southern Denmark, Department of Mathematics and Computer Science, Odense, Denmark"},{"name":"Federal University of Minas Gerais, Institute of Biological Sciences, Belo Horizonte, Brazil"}]},{"given":"Richard","family":"R\u00f6ttger","sequence":"additional","affiliation":[{"name":"University of Southern Denmark, Department of Mathematics and Computer Science, Odense, Denmark"}]},{"given":"Anne-Christin","family":"Hauschild","sequence":"additional","affiliation":[{"name":"University of Southern Denmark, Department of Mathematics and Computer Science, Odense, Denmark"}]},{"given":"Siomar","family":"de Castro Soares","sequence":"additional","affiliation":[{"name":"Federal University of Minas Gerais, Institute of Biological Sciences, Belo Horizonte, Brazil"},{"name":"Federal University of Tri\u00e2ngulo Mineiro, Department of Immunology, Microbiology and Parasitology, Uberaba, Brazil"}]},{"given":"Sebastian","family":"B\u00f6cker","sequence":"additional","affiliation":[{"name":"Friedrich-Schiller-Universit\u00e4t Jena, Faculty of Mathematics and Computer Science, Jena, Germany"}]},{"given":"Vasco","family":"Azevedo","sequence":"additional","affiliation":[{"name":"Federal University of Minas Gerais, Institute of Biological Sciences, Belo Horizonte, Brazil"}]},{"given":"Jan","family":"Baumbach","sequence":"additional","affiliation":[{"name":"University 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