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This is particularly challenging in a scientific context. For example, fewer than one third of tools and platforms for biological network representation, analysis, and visualisation have been available and supported over a period of 15 years. One of those tools is Vanted, which has been developed and actively supported over the past 20 years. In this work, we discuss sustainable software development in science and investigate which software tools for biological network representation, analysis, and visualisation are maintained over a period of at least 15 years. With Vanted as a case study, we highlight five key insights that we consider crucial for sustainable, long-term software development and software maintenance in science.<\/jats:p>","DOI":"10.1515\/jib-2025-0007","type":"journal-article","created":{"date-parts":[[2025,6,30]],"date-time":"2025-06-30T07:00:26Z","timestamp":1751266826000},"source":"Crossref","is-referenced-by-count":0,"title":["Sustainable software development in science \u2013 insights from 20\u202fyears of Vanted"],"prefix":"10.1515","volume":"22","author":[{"given":"Falk","family":"Schreiber","sequence":"first","affiliation":[{"name":"Department of Computer and Information Science , University of Konstanz , Konstanz , Germany"},{"name":"Faculty of Information Technology , Monash University , Clayton , Australia"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1788-9593","authenticated-orcid":false,"given":"Tobias","family":"Czauderna","sequence":"additional","affiliation":[{"name":"Faculty of Applied Computer Sciences and Biosciences , University of Applied Sciences Mittweida , Mittweida , Germany"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2134-1686","authenticated-orcid":false,"given":"Dimitar","family":"Garkov","sequence":"additional","affiliation":[{"name":"Department of Computer and Information Science , University of Konstanz , Konstanz , Germany"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-8600-6421","authenticated-orcid":false,"given":"Niklas","family":"Gr\u00f6ne","sequence":"additional","affiliation":[{"name":"Department of Computer and Information Science , University of Konstanz , Konstanz , Germany"}]},{"given":"Karsten","family":"Klein","sequence":"additional","affiliation":[{"name":"Department of Computer and Information Science , University of Konstanz , Konstanz , Germany"}]},{"given":"Matthias","family":"Lange","sequence":"additional","affiliation":[{"name":"Leibniz Institute of Plant Genetics and Crop Plant Research (IPK) Gatersleben , Seeland , Germany"}]},{"given":"Uwe","family":"Scholz","sequence":"additional","affiliation":[{"name":"Leibniz Institute of Plant Genetics and Crop Plant Research (IPK) Gatersleben , Seeland , Germany"}]},{"given":"Bj\u00f6rn","family":"Sommer","sequence":"additional","affiliation":[{"name":"Royal College of Art , London , UK"}]}],"member":"374","published-online":{"date-parts":[[2025,7,1]]},"reference":[{"key":"2025080610581960630_j_jib-2025-0007_ref_001","doi-asserted-by":"crossref","unstructured":"Hofest\u00e4dt, R, Kormeier, B, Lange, M, Schreiber, F, Sommer, B, Weise, S. 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