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This article proposes database-centric technology and architecture that aims to seamlessly integrate networking, artificial intelligence, and real-time control issues into a unified model of computing. The proposed methodology is also viable for the development of a framework that features simulation and rapid prototyping tools for smart and advanced industrial automation. The full expression of the potentialities in the presented approach is expected in particular for applications where tiny and distributed embedded devices collaborate to a shared computing task of relevant complexity.<\/jats:p>","DOI":"10.1515\/jisys-2016-0281","type":"journal-article","created":{"date-parts":[[2017,7,14]],"date-time":"2017-07-14T06:01:39Z","timestamp":1500012099000},"page":"659-679","source":"Crossref","is-referenced-by-count":20,"title":["A Database-Centric Framework for the Modeling, Simulation, and Control of Cyber-Physical Systems in the Factory of the Future"],"prefix":"10.1515","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0265-1598","authenticated-orcid":false,"given":"Andrea","family":"Bonci","sequence":"first","affiliation":[{"name":"Department of Information Engineering (DII) , Universit\u00e1 Politecnica delle Marche , via Brecce Bianche, 60131 Ancona , Italy"}]},{"given":"Massimiliano","family":"Pirani","sequence":"additional","affiliation":[{"name":"Department of Information Engineering (DII) , Universit\u00e1 Politecnica delle Marche , via Brecce Bianche, Ancona , Italy"}]},{"given":"Sauro","family":"Longhi","sequence":"additional","affiliation":[{"name":"Department of Information Engineering (DII) , Universit\u00e1 Politecnica delle Marche , via Brecce Bianche, Ancona , Italy"}]}],"member":"374","published-online":{"date-parts":[[2017,7,14]]},"reference":[{"key":"2025120523275882361_j_jisys-2016-0281_ref_001_w2aab3b7c10b1b6b1ab1b7b1Aa","doi-asserted-by":"crossref","unstructured":"A. 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