{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T04:47:58Z","timestamp":1747198078665,"version":"3.40.5"},"reference-count":9,"publisher":"Walter de Gruyter GmbH","issue":"1","license":[{"start":{"date-parts":[[2023,2,15]],"date-time":"2023-02-15T00:00:00Z","timestamp":1676419200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,4,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec id=\"j_almed-2023-0004_abs_001\">\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>\n                     <jats:italic>Ureaplasma<\/jats:italic> species are the most frequently isolated microorganisms in cases of spontaneous preterm labor, premature rupture of the membranes, or chorioamnionitis.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_almed-2023-0004_abs_002\">\n                  <jats:title>Case presentation<\/jats:title>\n                  <jats:p>A woman at 28<jats:sup>+6<\/jats:sup> weeks of gestation with no apparent history of interest presented at the hospital with contractions. Upon suspicion of chorioamnionitis, the patient was admitted for a low segment transverse cesarean section, which was completed without any complications. The patient was discharged at 7\u00a0days. The newborn remained stable and showed no clinical signs of infection. However, on suspicion of chorioamnionitis, empirical treatment with intravenous ampicillin (2\u00a0g every 6\u00a0h) and gentamicin (5\u00a0mg\/kg once daily) was initiated. Samples of pharyngeal\/tonsillar, ear, and anal\/rectal exudates were collected. At 24\u00a0h, all samples were positive for <jats:italic>Ureaplasma parvum<\/jats:italic>. Empirical treatment was suspended, and treatment with intravenous azithromycin was initiated (12\u00a0mg once daily). Endocervical and placental exudates were also positive for <jats:italic>U.\u00a0parvum<\/jats:italic>. Fifty-two days after birth, the newborn was discharged.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_almed-2023-0004_abs_003\">\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>The relationship between <jats:italic>Ureaplasma<\/jats:italic> spp. colonization and perinatal disease seem to be clear. However, the high frequency of vaginal <jats:italic>Ureaplasma<\/jats:italic> spp<jats:italic>.<\/jats:italic> colonization and high rates of term labor among pregnant women with this colonization make further studies necessary.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1515\/almed-2023-0004","type":"journal-article","created":{"date-parts":[[2023,2,14]],"date-time":"2023-02-14T12:52:11Z","timestamp":1676379131000},"page":"128-129","source":"Crossref","is-referenced-by-count":0,"title":["Chorioamnionitis secondary to <i>Ureaplasma parvum<\/i> infection: a case report"],"prefix":"10.1515","volume":"4","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5806-6788","authenticated-orcid":false,"given":"Antonio","family":"Moreno-Flores","sequence":"first","affiliation":[{"name":"Hospital Universitario Lucus Augusti , Lugo , Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda","family":"Dom\u00ednguez-Landesa","sequence":"additional","affiliation":[{"name":"Hospital Universitario Lucus Augusti , Lugo , Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda Guadalupe","family":"V\u00e1zquez-L\u00f3pez","sequence":"additional","affiliation":[{"name":"Hospital Universitario Lucus Augusti , Lugo , Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Sante-Fern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Hospital Universitario Lucus Augusti , Lugo , Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","published-online":{"date-parts":[[2023,2,15]]},"reference":[{"key":"2023062110182175556_j_almed-2023-0004_ref_001","doi-asserted-by":"crossref","unstructured":"Rittenschober-B\u00f6hm, J, Waldhoer, T, Schulz, SM, Pimpel, B, Goeral, K, Kasper, DC, et al.. Vaginal Ureaplasma parvum serovars and spontaneous preterm birth. Am J Obstet Gynecol 2019;22:594.e1\u20139. https:\/\/doi.org\/10.1016\/j.ajog.2019.01.237.","DOI":"10.1016\/j.ajog.2019.01.237"},{"key":"2023062110182175556_j_almed-2023-0004_ref_002","doi-asserted-by":"crossref","unstructured":"Venturelli, N, Zeis, A, De Beritto, T, Hageman, JR. Ureasplasma and its role in adverse perinatal outcomes: a review. Neoreviews 2021;22:e574\u201384. https:\/\/doi.org\/10.1542\/neo.22-9-e574.","DOI":"10.1542\/neo.22-9-e574"},{"key":"2023062110182175556_j_almed-2023-0004_ref_003","doi-asserted-by":"crossref","unstructured":"Motomura, K, Romero, R, Xu, Y, Theis, KR, Galaz, J, Winters, AD, et al.. Intra-amniotic infection with Ureaplasma parvum causes preterm birth and neonatal mortality that are prevented by treatment with clarithromycin. MBio 2020;11:1\u201323. https:\/\/doi.org\/10.1128\/mbio.00797-20.","DOI":"10.1128\/mBio.00797-20"},{"key":"2023062110182175556_j_almed-2023-0004_ref_004","doi-asserted-by":"crossref","unstructured":"Sweeney, EL, Dando, SJ, Kallapur, SG, Knox, CL. The human Ureaplasma species as causative agents of chorioamnionitis. Clin Microbiol Rev 2017;30:349\u201379. https:\/\/doi.org\/10.1128\/cmr.00091-16.","DOI":"10.1128\/CMR.00091-16"},{"key":"2023062110182175556_j_almed-2023-0004_ref_005","doi-asserted-by":"crossref","unstructured":"Tantengco, OAG, Yanagihara, I. Current understanding and treatment of intra-amniotic infection with Ureaplasma spp. J Obstet Gynaecol Res 2019;45:1796\u2013808. https:\/\/doi.org\/10.1111\/jog.14052.","DOI":"10.1111\/jog.14052"},{"key":"2023062110182175556_j_almed-2023-0004_ref_006","doi-asserted-by":"crossref","unstructured":"Sprong, KE, Mabenge, M, Wright, CA, Govender, S. Ureaplasma species and preterm birth: current perspectives. Crit Rev Microbiol 2020;46:169\u201381. https:\/\/doi.org\/10.1080\/1040841x.2020.1736986.","DOI":"10.1080\/1040841X.2020.1736986"},{"key":"2023062110182175556_j_almed-2023-0004_ref_007","doi-asserted-by":"crossref","unstructured":"Oliveira, CNT, Oliveira, MTS, Oliveira, HBM, Silva, LSC, Freire, RS, Santos J\u00fanior, MN, et al.. Association of spontaneous abortion and Ureaplasma parvum detected in placental tissue. Epidemiol Infect 2020;148:e126. https:\/\/doi.org\/10.1017\/s0950268820001302.","DOI":"10.1017\/S0950268820001302"},{"key":"2023062110182175556_j_almed-2023-0004_ref_008","doi-asserted-by":"crossref","unstructured":"Suzuki, Y, Horie, K, Yada, Y, Kono, Y, Hirashima, C, Usui, R, et al.. Vaginal Ureaplasma species increase chorioamnionitis in very preterm infants with preterm premature rupture of the membranes at <28\u00a0weeks of gestation. Eur J Clin Microbiol Infect Dis 2018;37:2371\u201380. https:\/\/doi.org\/10.1007\/s10096-018-3385-5.","DOI":"10.1007\/s10096-018-3385-5"},{"key":"2023062110182175556_j_almed-2023-0004_ref_009","doi-asserted-by":"crossref","unstructured":"Stol, K, Jans, J, Ott de Bruin, L, Unger, W, van Rossum, A. Perinatal infections with Ureaplasma. Pediatr Infect Dis J 2021;40:S26\u201330. https:\/\/doi.org\/10.1097\/inf.0000000000002859.","DOI":"10.1097\/INF.0000000000002859"}],"container-title":["Advances in Laboratory Medicine \/ Avances en Medicina de Laboratorio"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.degruyter.com\/document\/doi\/10.1515\/almed-2023-0004\/xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.degruyter.com\/document\/doi\/10.1515\/almed-2023-0004\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,21]],"date-time":"2023-06-21T10:18:49Z","timestamp":1687342729000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.degruyter.com\/document\/doi\/10.1515\/almed-2023-0004\/html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2,15]]},"references-count":9,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2023,2,9]]},"published-print":{"date-parts":[[2023,4,11]]}},"alternative-id":["10.1515\/almed-2023-0004"],"URL":"https:\/\/doi.org\/10.1515\/almed-2023-0004","relation":{},"ISSN":["2628-491X"],"issn-type":[{"type":"electronic","value":"2628-491X"}],"subject":[],"published":{"date-parts":[[2023,2,15]]}}}