{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T12:52:22Z","timestamp":1787316742297,"version":"build-2736575974"},"reference-count":45,"publisher":"Springer Science and Business Media LLC","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Neospora caninum is considered one of the major causes of abortion in cattle. The aim of this study was to examine and quantify the extent of the infection in cattle in a representative region of Argentina (La Pampa, province). An average sample size of 36 sera per herd was selected from 97 beef and 24 dairy herds. A total of 4334 serum samples were tested for specific anti- Neospora caninum IgG using an indirect-ELISA and 302 seropositive-ELISA sera were re-examined using an Avidity-ELISA procedure for N.caninum. The overall estimated seroprevalence for N.caninun was 9.6% (95%CI: 8.7%; 10.5%). Levels of seroprevalence were significantly different in beef 7.0% and dairy 20.3% cattle. Disease distribution seems to be associated with climatic conditions as well as the management system. Cows in the east and central regions were at a 4.5-fold and 2.0-fold higher risk, respectively, of being N. caninum seropositive compared with cows in west region. Levels of recent infection were evaluated through an avidity ELISA in seropositive animals, being registered a 0.56% and a 1.71% of recent infection in beef and dairy cattle respectively (p = 0.006). The results revealed that dairy cows had 3.1(95%CI: 1.4; 7.0) higher risk of contracting Neoporosis through horizontal transmission than beef cows. A relationship between Brucella abortus and N. caninum seroprevalence was also observed. The risk of being N. caninum seropositive was two times higher where Brucellosis seroprevalence was &gt;3.5%. These results reveal the distribution of N. caninum infection in the cattle population in La Pampa, Argentina<\/jats:p>","DOI":"10.1515\/ap-2015-0039","type":"journal-article","created":{"date-parts":[[2015,4,20]],"date-time":"2015-04-20T05:27:21Z","timestamp":1429507641000},"source":"Crossref","is-referenced-by-count":18,"title":["Seroepidemiological study of Neospora caninum in beef and dairy cattle in La Pampa, Argentina"],"prefix":"10.1007","volume":"60","author":[{"given":"Marcelo","family":"Fort","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martyn","family":"Edelsten","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen","family":"Maley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabeth","family":"Innes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref321","first-page":"38","article-title":"Co - infection of water buffaloes in Punjab Pakistan with Neospora caninum and Brucella abortus","author":"Nasir","year":"2014","journal-title":"Turk J Vet Anim Sci"},{"key":"ref11","first-page":"61","article-title":"Bovine Brucellosis in Argentina and bordering countries : update and emerging","author":"Aznar","year":"2014","journal-title":"Transboundary diseases"},{"key":"ref161","first-page":"78","article-title":"Neospora caninum ( Apicomplexa ) in stillborn goat of","author":"Dubey","year":"1992","journal-title":"Journal Parasitolology"},{"key":"ref421","doi-asserted-by":"crossref","first-page":"1705","DOI":"10.1016\/S0020-7519(99)00143-5","article-title":"Neospora caninum infections in bovine foetuses and dairy cows with abortions in Argentina for","volume":"29","author":"Venturini","year":"1999","journal-title":"International Journal Parasitology"},{"key":"ref121","first-page":"74","article-title":"Herd - level risk factors for Neospora caninum seroprevalence in dairy farms in southern Brazil","author":"Corbellini","year":"2006","journal-title":"Preventive Veterinary Medicine"},{"key":"ref141","doi-asserted-by":"crossref","first-page":"146","DOI":"10.2307\/3282954","article-title":"Neospora caninumlike protozoon associated with fatal myelitis in newborn calves of","volume":"75","author":"Dubey","year":"1989","journal-title":"Journal Parasitolology"},{"key":"ref351","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1016\/S0020-7519(99)00084-3","article-title":"Seroprevalence of Neospora caninum infection in dairy and beef cattle in Spain for","volume":"29","author":"Quintanilla","year":"1999","journal-title":"International Journal Parasitology"},{"key":"ref71","first-page":"137","article-title":"Santa Supranational comparison of Neospora caninum seroprevalences in cattle in Germany , the Netherlands Spain and Sweden","author":"Bartels","year":"2006","journal-title":"Veterinary Parasitology"},{"key":"ref331","first-page":"90","article-title":"Serological survey and first finding of Neospora caninum in Taiwan , and the detection of its antibodies in various body fluids of cattle of","author":"Ooi","year":"2000","journal-title":"Journal Veterinary Parasitology"},{"key":"ref21","first-page":"217","article-title":"Spatial associations among density of cattle , abundance of wild canids , and seroprevalence to Neospora caninum in a population of beef calves Medical","author":"Barling","year":"2000","journal-title":"Journal American Veterinary Association"},{"key":"ref241","first-page":"56","article-title":"Abortions , fetal death , and stillbirths in pregnant pygmy goats inoculated with tachyzoites of Neospora caninum","author":"Lindsay","year":"1995","journal-title":"American Journal of Veterinary Research"},{"key":"ref441","first-page":"164","article-title":"seroprevalence of Neospora caninum in dairy cattle ranches with high abortion rate : special emphasis to serologic co - existence with Toxoplasma gondii Brucella abortus and Listeria monocytogenes","author":"Yildiz","year":"2009","journal-title":"Veterinary Parasitology"},{"key":"ref131","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1016\/S0020-7519(99)00094-6","article-title":"Significance of Neospora caninum in British dairy cattle determined by estimation of seroprevalence in normally calving cattle and aborting cattle for","volume":"29","author":"Davison","year":"1999","journal-title":"The International Journal Parasitology"},{"key":"ref301","first-page":"107","article-title":"Seroepidemiology of beef and dairy herds and fetal study of Neospora caninum in Argentina of","author":"Moore","year":"2002","journal-title":"Journal Veterinary Parasitology"},{"key":"ref371","first-page":"90","article-title":"Neospora caninum seroprevalence and associated risk factors in beef cattle in the northwestern United States of","author":"Sanderson","year":"2000","journal-title":"Journal Veterinary Parasitology"},{"key":"ref401","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1080\/00480169.2000.36182","article-title":"Prevalence of Neospora antibodies in beef cattle in New Zealand","volume":"48","author":"Tennent","year":"2000","journal-title":"New Zealand Veterinary Journal"},{"key":"ref271","first-page":"145","article-title":"Seroprevalence of N caninum and abortion in dairy cows in northern Spain","author":"Mainar","year":"1999","journal-title":"Veterinary Record"},{"key":"ref01","first-page":"207","article-title":"Evaluation of abortions in cattle attributable to neosporosis in select dairy herd in California Medical","author":"Anderson","year":"1995","journal-title":"Journal American Veterinary Association"},{"key":"ref41","first-page":"3","article-title":"Neosporalike encephalomyelitis in a calf : pathology , ultrastructure and immunoreactivity Diagnostic Investigation","author":"Barr","year":"1991","journal-title":"Journal of Veterinary"},{"key":"ref31","first-page":"52","article-title":"Ranch - management factors associated with antibody seropositivity for Neospora caninum in consignments of beef calves in Texas , USA","author":"Barling","year":"2001","journal-title":"Preventive Veterinary Medicine"},{"key":"ref211","first-page":"150","article-title":"Epidemiological investigations of abortions due to Neospora caninum on Swiss dairy farms","author":"Hassig","year":"2002","journal-title":"Veterinary Record"},{"key":"ref361","first-page":"64","article-title":"Effect of neosporosis on productive and reproductive performance of dairy cattle in Costa Rica","author":"Romero","year":"2005","journal-title":"Theriogenology"},{"key":"ref261","first-page":"52","article-title":"Relationship between rainfall and Neospora caninum - associated abortion in two dairy herds in a dry environment of","author":"Lopez","year":"2005","journal-title":"Journal Veterinary Medicine Series B"},{"key":"ref201","first-page":"149","article-title":"Neospora caninum in persistently infected , pregnant cows : spontaneous transplacental infection is associated with an acute increase in maternal antibody","author":"Guy","year":"2001","journal-title":"Veterinary Record"},{"key":"ref291","first-page":"217","article-title":"Evidence of point - source exposure to Neospora caninum and protective immunity in a herd of beef cows","author":"McAllister","year":"2000","journal-title":"JAVMA"},{"key":"ref221","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1556\/AVet.54.2006.4.6","article-title":"Seroprevalence of neosporosis in beef and dairy cattle breeds in Northeast Hungary","volume":"54","author":"Hornok","year":"2006","journal-title":"Acta Veterinaria Hungarica"},{"key":"ref411","first-page":"81","article-title":"Veterinary nd Edition Secular and seasonal trends of Neospora abortion in California dairy cows","author":"Thrusfield","year":"1997","journal-title":"Epidemiology Blackwell Sciences Journal of Parasitology"},{"key":"ref81","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1007\/BF00942230","article-title":"Unidentified cyst - forming sporozoon causing encephalomyelitis and myositis in dogs","volume":"70","author":"Bjerkas","year":"1984","journal-title":"Z Parasitenkd"},{"key":"ref231","first-page":"130","article-title":"Seroprevalence of Neospora caninum in dairy and beef cattle with reproductive disorders in Japan","author":"Koiwai","year":"2005","journal-title":"Veterinary Parasitology"},{"key":"ref91","first-page":"11","article-title":"An IgG avidity Elisa to discriminate between recent and chronic Neospora caninum infections","author":"Bjorkman","year":"1999","journal-title":"Journal of Veterinary Diagnostic Investigation"},{"key":"ref151","first-page":"76","article-title":"Fatal congenital Neospora caninum infection in a Lamb of","author":"Dubey","year":"1990","journal-title":"Journal Parasitolology"},{"key":"ref171","first-page":"20","article-title":"Epidemiology and Control of Neosporosis and Neospora caninum","author":"Dubey","year":"2007","journal-title":"Clinical Microbiology Reviews"},{"key":"ref111","first-page":"143","article-title":"Neospora caninum - associated abortion in dairy herd in Argentina","author":"Campero","year":"1998","journal-title":"Veterinary Record"},{"key":"ref431","first-page":"1995","article-title":"Characteristics of Neospora caninum - associated abortion storms in dairy herds in the Netherlands","author":"Wouda","year":"1999","journal-title":"Theriogenology"},{"key":"ref381","first-page":"75","article-title":"Experimental Leptospira borgpetersennii serovar hardjo infection of pregnant cattle","author":"Smith","year":"1997","journal-title":"Australian Veterinary Journal"},{"key":"ref61","first-page":"1995","article-title":"Risk factors for Neospora caninum - associated abortion storms in dairy herds in the Netherlands to","author":"Bartels","year":"1999","journal-title":"Theriogenology"},{"key":"ref311","first-page":"161","article-title":"Risk factors associated with Neospora caninum infections in cattle in Argentina of","author":"Moore","year":"2009","journal-title":"Journal Veterinary Parasitology"},{"key":"ref281","first-page":"20","article-title":"Identification of Neospora antigens recognized by CD T cells and immune sera from experimentally infected cattle","author":"Marks","year":"1998","journal-title":"Parasite Immunology"},{"key":"ref251","first-page":"103","article-title":"Survival of nonsporulated toxoplama goondii oocists under refrigerator conditions of","author":"Lindsay","year":"2002","journal-title":"Journal Veterinary Parasitology"},{"key":"ref51","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1177\/030098589102800202","article-title":"Neosporalike protozoal infections associated with bovine abortion","volume":"28","author":"Barr","year":"1992","journal-title":"Veterinary Pathology"},{"key":"ref191","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1016\/S0020-7519(98)00006-X","article-title":"Molecular and immunodiagnostic investigations on bovine neosporosis in Switzerland for","volume":"28","author":"Gottstein","year":"1998","journal-title":"The International Journal Parasitology"},{"key":"ref181","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/S0304-4017(99)00129-6","article-title":"Seroprevalence of Neospora caninum in dairy cattle in Bahia Brasil","volume":"86","author":"Gondim","year":"1999","journal-title":"Veterinary Parasitology"},{"key":"ref101","first-page":"141","article-title":"Neosporosis and bovine abortion in Scotland","author":"Buxton","year":"1997","journal-title":"Veterinary Record"},{"key":"ref341","first-page":"79","article-title":"A multiple antigen ELISA to detect Neospora - specific antibodies in bovine sera , bovine foetal fluids , ovine and caprine sera of","author":"Osawa","year":"1998","journal-title":"Journal Veterinary Parasitology"},{"key":"ref391","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/S0304-4017(99)00130-2","article-title":"Seroprevalence of antibodies to Neospora caninum and associated abortion in dairy cattle from central Thailand","volume":"86","author":"Suteeraparp","year":"1999","journal-title":"Veterinary Parasitology"}],"container-title":["Acta Parasitologica"],"original-title":[],"link":[{"URL":"https:\/\/www.degruyter.com\/view\/j\/ap.2015.60.issue-2\/ap-2015-0039\/ap-2015-0039.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,12,14]],"date-time":"2020-12-14T11:39:51Z","timestamp":1607945991000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.degruyter.com\/view\/j\/ap.2015.60.issue-2\/ap-2015-0039\/ap-2015-0039.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,1,1]]},"references-count":45,"journal-issue":{"issue":"2"},"URL":"https:\/\/doi.org\/10.1515\/ap-2015-0039","relation":{},"ISSN":["1896-1851","1230-2821"],"issn-type":[{"value":"1896-1851","type":"electronic"},{"value":"1230-2821","type":"print"}],"subject":[],"published":{"date-parts":[[2015,1,1]]}}}