{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T12:33:15Z","timestamp":1763037195177},"reference-count":84,"publisher":"Springer Science and Business Media LLC","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,9,25]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Echinococcus multilocularis<\/jats:italic>is a zoonotic tapeworm of medical and veterinary importance that occasionally infects accidental intermediate hosts causing severe disease or even death. In dogs, alveolar echinococcosis has been reported mainly in central Europe and Canada. The paper presents clinical, biochemical and histological signs of alveolar echinococcosis in a dog from Slovakia and the results of mitochondrial<jats:italic>nad1<\/jats:italic>gene analysis. In 2016, 11-years old Siberian husky female suffering from inappetence was presented to the Veterinary Clinic in \u017dilina. Biochemical blood examination and blood count showed only minor changes, but abdominal ultrasonography showed the hepatomegaly and the presence of nonhomogeneous hypodense lobulated formation in the left liver lobe. Histological and molecular examinations of excided tissue confirmed the diagnosis of alveolar echinococcosis of the liver. BLAST analysis of<jats:italic>E<\/jats:italic>.<jats:italic>multilocularis nad1<\/jats:italic>gene revealed that the nucleotide sequence did not exactly match the previously identified M1 (AJ237639) and\/or M2 genotype (AJ237640). In total, two single nucleotide polymorphisms (SNPs) occurred within overlapping region of<jats:italic>nad1<\/jats:italic>gene. In the discussion, clinical and laboratory findings of the infection in other dog patients are compared and the possibilities of diagnosis and therapy of the disease are discussed.<\/jats:p>","DOI":"10.1515\/ap-2018-0058","type":"journal-article","created":{"date-parts":[[2018,7,12]],"date-time":"2018-07-12T17:18:54Z","timestamp":1531415934000},"page":"486-494","source":"Crossref","is-referenced-by-count":8,"title":["Alveolar echinococcosis in a dog; analysis of clinical and histological findings and molecular identification of Echinococcus multilocularis"],"prefix":"10.1007","volume":"63","author":[{"given":"Daniela","family":"Antolov\u00e1","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bronislava","family":"V\u00edchov\u00e1","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00falia","family":"Jaro\u0161ov\u00e1","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Viliam","family":"G\u00e1l","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Branislav","family":"Baju\u017e\u00edk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref451","first-page":"259","article-title":"Detection of Echinococcus multilocularis in wild boars in France using PCR techniques against larval form","volume":"15","year":"2005","journal-title":"Veterinary Parasitology"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1515\/helmin-2016-0026","article-title":"Pyogenic liver abscess in a child with concomitant infections \u2014 Staphylococcus aureus, Echinococcus multilocularis and Mycobacterium tuberculosis","volume":"53","year":"2016","journal-title":"Helminthologia"},{"key":"ref71","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/S0304-4017(01)00424-1","article-title":"Veterinary aspects of alveolar echinococcosis \u2013 a zoonosis of public health significance","volume":"98","year":"2001","journal-title":"Veterinary Parasitology"},{"key":"ref281","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1007\/BF00931785","article-title":"Phylogenetic relationships within Taenia taeniaeformis variants and other taeniid cestodes inferred from the nucleotide sequence of the cytochrome c oxidase subunit I gene","volume":"81","year":"1995","journal-title":"Parasitology Research"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1111\/j.1939-165X.2012.00425.x","article-title":"What is your diagnosis? Peritoneal fluid from a dog with abdominal pain","volume":"41","year":"2012","journal-title":"Veterinary Clinical Pathology"},{"key":"ref291","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1111\/vcp.12210","article-title":"What is your diagnosis? Fluid aspirated from an abdominal mass in a dog","volume":"44","year":"2015","journal-title":"Veterinary Clinical Pathology"},{"key":"ref431","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/S0022-2836(05)80360-2","article-title":"Basic local alignment search tool","volume":"215","year":"1990","journal-title":"Journal of Molecular Biology"},{"key":"ref671","first-page":"171","article-title":"A case of alveolar echinococcosis in a horse","volume":"32","year":"1984","journal-title":"Japanese Journal of Veterinary Research"},{"key":"ref761","first-page":"551","article-title":"Hepatic alveolar hydatid disease (Echinococcus multilocularis) in a boxer dog from southern Ontario","volume":"55","year":"2014","journal-title":"Canadian Veterinary Journal"},{"key":"ref01","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/S0022-2836(05)80360-2","article-title":"Basic local alignment search tool","volume":"215","year":"1990","journal-title":"Journal of Molecular Biology"},{"key":"ref411","first-page":"828","article-title":"A dog with alveolar echinococcosis: the larval stage of the fox tapeworm","volume":"132","year":"2007","journal-title":"Tijdschrift Voor Diergeneeskunde"},{"key":"ref231","doi-asserted-by":"crossref","first-page":"155","DOI":"10.2478\/s11687-011-0023-5","article-title":"Fox tapeworm (Echinococcus multilocularis) in Slovakia \u2013 summarizing the long-term monitoring","volume":"48","year":"2011","journal-title":"Helminthologia"},{"key":"ref751","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1016\/j.ijpara.2007.11.008","article-title":"Development of a new PCR protocol for the detection of species and genotypes (strains) of Echinococcus in formalin-fixed, paraffin-embedded tissues","volume":"38","year":"2008","journal-title":"International Journal for Parasitology"},{"key":"ref381","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/S0065-308X(08)60356-5","article-title":"The nature, extent and significance of variation within the genus Echinococcus","volume":"27","year":"1988","journal-title":"Advances in Parasitology"},{"key":"ref701","first-page":"59","volume-title":"Alveolar echinococcosis: Strategy for eradication of alveolar echinococcosis of the liver.","year":"1996"},{"key":"ref391","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1016\/S1471-4922(02)02358-9","article-title":"Towards a taxonomic revison of the genus Echinococcus","volume":"18","journal-title":"Trends in Parasitology"},{"key":"ref571","first-page":"81","article-title":"Unexpected diversity of the cestode Echinococcus multilocularis in wildlife in Canada","volume":"3","year":"2014","journal-title":"International Journal for Parasitology: Parasites and Wildlife"},{"key":"ref721","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1111\/vcp.12210","article-title":"What is your diagnosis? Fluid aspirated from an abdominal mass in a dog","volume":"44","year":"2015","journal-title":"Veterinary Clinical Pathology"},{"key":"ref511","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1007\/s15010-016-0918-7","article-title":"Autochtonous human alveolar echinococcosis in a Hungarian patient","volume":"45","year":"2017","journal-title":"Infection"},{"key":"ref371","doi-asserted-by":"crossref","first-page":"2725","DOI":"10.1093\/molbev\/mst197","article-title":"MEGA6: molecular evolutionary genetics analysis version 6.0","volume":"30","year":"2013","journal-title":"Molecular Biology and Evolution"},{"key":"ref531","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1128\/CMR.17.1.107-135.2004","article-title":"Biological, epidemiological, and clinical aspects of echinococcosis, a zoonosis of increasing concern","volume":"17","year":"2004","journal-title":"Clinical Microbiology Reviews"},{"key":"ref261","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1016\/j.parint.2009.07.010","article-title":"Geographic pattern of genetic variation in the fox tapeworm Echinococcus multilocularis","volume":"58","year":"2009","journal-title":"Parasitology International"},{"key":"ref221","first-page":"408","article-title":"Lethal alveolar echinococcosis in a dog: clinical symptoms and pathology","volume":"126","year":"2013","journal-title":"Berliner und Munchener Tierarztliche Wochenschrift"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.actatropica.2009.11.001","article-title":"Writing Panel for the WHO-IWGE. Expert consensus for the diagnosis and treatment of cystic and alveolar echinococcosis in humans","volume":"114","year":"2010","journal-title":"Acta Tropica"},{"key":"ref61","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1136\/vr.103470","article-title":"Clinical presentation, diagnosis, therapy and outcome of alveolar echinococcosis in dogs","volume":"177","year":"2015","journal-title":"Veterinary Record"},{"key":"ref51","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/0166-6851(92)90109-W","article-title":"Genetic variants within the genus Echinococcus identified by mitochondrial DNA sequencing","volume":"54","year":"1992","journal-title":"Molecular and Biochemical Parasitology"},{"key":"ref141","first-page":"81","article-title":"Unexpected diversity of the cestode Echinococcus multilocularis in wildlife in Canada","volume":"3","year":"2014","journal-title":"International Journal for Parasitology: Parasites and Wildlife"},{"key":"ref311","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1111\/j.1740-8261.2004.04074.x","article-title":"Radiographic, ultrasonographic, and computed tomographic appearance of alveolar echinococcosis in dogs","volume":"45","year":"2004","journal-title":"Veterinary Radiology and Ultrasound"},{"key":"ref611","first-page":"018","article-title":"First detection of Echinococcus multilocularis in dogs in highly endemic area of Poland","volume":"63","year":"2016","journal-title":"Folia Parasitologica"},{"key":"ref351","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1089\/vbz.2016.2089","article-title":"Contribution to the diagnosis and treatment of life-threatening parasitosis caused by the parasite Echinococcus multilocularis","volume":"17","year":"2017","journal-title":"Vector-Borne and Zoonotic Diseases"},{"key":"ref131","first-page":"267","article-title":"Pulmonary Echinococcus multilocularis metastasis in a dog","volume":"56","year":"2015","journal-title":"Canadian Veterinary Journal"},{"key":"ref641","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1136\/vr.141.2.49","article-title":"Larval Echinococcus multilocularis infection in a dog","volume":"141","year":"1997","journal-title":"Veterinary Record"},{"key":"ref801","doi-asserted-by":"crossref","first-page":"2725","DOI":"10.1093\/molbev\/mst197","article-title":"MEGA6: molecular evolutionary genetics analysis version 6.0","volume":"30","year":"2013","journal-title":"Molecular Biology and Evolution"},{"key":"ref811","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/S0065-308X(08)60356-5","article-title":"The nature, extent and significance of variation within the genus Echinococcus","volume":"27","year":"1988","journal-title":"Advances in Parasitology"},{"key":"ref541","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1186\/s13071-017-2369-0","article-title":"Dogs as victims of their own worms: Serological diagnosis of canine alveolar echinococcosis","volume":"10","year":"2017","journal-title":"Parasites & Vectors"},{"key":"ref681","first-page":"713","article-title":"A molecular phylogeny of the genus Echinococcus inferred from complete mitochondrial genomes","volume":"134","year":"2007","journal-title":"Parasitology"},{"key":"ref331","first-page":"551","article-title":"Hepatic alveolar hydatid disease (Echinococcus multilocularis) in a boxer dog from southern Ontario","volume":"55","year":"2014","journal-title":"Canadian Veterinary Journal"},{"key":"ref691","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1016\/j.parint.2009.07.010","article-title":"Geographic pattern of genetic variation in the fox tapeworm Echinococcus multilocularis","volume":"58","year":"2009","journal-title":"Parasitology International"},{"key":"ref421","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1186\/s13071-017-2172-y","article-title":"Genetic variation of mitochondrial genes among Echinococcus multilocularis isolates collected in western China","volume":"10","year":"2017","journal-title":"Parasites & Vectors"},{"key":"ref551","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1186\/1746-6148-9-159","article-title":"Unusual presentation of alveolar echinococcosis as prostatic ad paraprostatic cyst in a dog","volume":"9","year":"2013","journal-title":"BMC Veterinary Research"},{"key":"ref791","first-page":"512","article-title":"Estimation of the number of nucleotide substitutions in the control region of mitochondrial DNA in humans and chimpanzees","volume":"10","year":"1993","journal-title":"Molecular Biology and Evolution"},{"key":"ref441","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1515\/helmin-2016-0026","article-title":"Pyogenic liver abscess in a child with concomitant infections \u2014 Staphylococcus aureus, Echinococcus multilocularis and Mycobacterium tuberculosis","volume":"53","year":"2016","journal-title":"Helminthologia"},{"key":"ref461","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1111\/j.1939-165X.2012.00425.x","article-title":"What is your diagnosis? Peritoneal fluid from a dog with abdominal pain","volume":"41","year":"2012","journal-title":"Veterinary Clinical Pathology"},{"key":"ref481","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/0166-6851(92)90109-W","article-title":"Genetic variants within the genus Echinococcus identified by mitochondrial DNA sequencing","volume":"54","year":"1992","journal-title":"Molecular and Biochemical Parasitology"},{"key":"ref821","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1016\/S1471-4922(02)02358-9","article-title":"Towards a taxonomic revison of the genus Echinococcus","volume":"18","journal-title":"Trends in Parasitology"},{"key":"ref151","doi-asserted-by":"crossref","first-page":"309","DOI":"10.5326\/15473317-34-4-309","article-title":"Surgical and chemotherapeutiv treatment of alveolar echinococcosis in a dog","volume":"34","year":"1998","journal-title":"Journal of American Animal Hospital Association"},{"key":"ref771","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.vetpar.2006.05.026","article-title":"Serological diagnosis of canine alveolar echinococcosis","volume":"141","year":"2006","journal-title":"Veterinary Parasitology"},{"key":"ref711","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1007\/BF00931785","article-title":"Phylogenetic relationships within Taenia taeniaeformis variants and other taeniid cestodes inferred from the nucleotide sequence of the cytochrome c oxidase subunit I gene","volume":"81","year":"1995","journal-title":"Parasitology Research"},{"key":"ref361","first-page":"512","article-title":"Estimation of the number of nucleotide substitutions in the control region of mitochondrial DNA in humans and chimpanzees","volume":"10","year":"1993","journal-title":"Molecular Biology and Evolution"},{"key":"ref651","first-page":"408","article-title":"Lethal alveolar echinococcosis in a dog: clinical symptoms and pathology","volume":"126","year":"2013","journal-title":"Berliner und Munchener Tierarztliche Wochenschrift"},{"key":"ref21","first-page":"259","article-title":"Detection of Echinococcus multilocularis in wild boars in France using PCR techniques against larval form","volume":"15","year":"2005","journal-title":"Veterinary Parasitology"},{"key":"ref471","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.actatropica.2009.11.001","article-title":"Writing Panel for the WHO-IWGE. Expert consensus for the diagnosis and treatment of cystic and alveolar echinococcosis in humans","volume":"114","year":"2010","journal-title":"Acta Tropica"},{"key":"ref741","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1111\/j.1740-8261.2004.04074.x","article-title":"Radiographic, ultrasonographic, and computed tomographic appearance of alveolar echinococcosis in dogs","volume":"45","year":"2004","journal-title":"Veterinary Radiology and Ultrasound"},{"key":"ref831","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/j.parint.2013.08.011","article-title":"Echinococcus multilocularis infection of a ring-tailed lemur (Lemur catta) and a nutria (Myocastor coypus) in a French zoo","volume":"62","year":"2013","journal-title":"Parasitology International"},{"key":"ref251","first-page":"713","article-title":"A molecular phylogeny of the genus Echinococcus inferred from complete mitochondrial genomes","volume":"134","year":"2007","journal-title":"Parasitology"},{"key":"ref91","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1016\/j.vetpar.2008.07.030","article-title":"Echinococcus multilocularis infections in domestic dogs and cats from Germany and other European countries","volume":"157","year":"2008","journal-title":"Veterinary Parasitology"},{"key":"ref591","first-page":"123","article-title":"A case of alveolar hydatid disease in a dog: domestic animals as rare incidental intermediate hosts for Echinococcus multilocularis","volume":"149","year":"2007","journal-title":"Schweizer Archiv Fur Tierheilkunde"},{"key":"ref781","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1089\/vbz.2016.2089","article-title":"Contribution to the diagnosis and treatment of life-threatening parasitosis caused by the parasite Echinococcus multilocularis","volume":"17","year":"2017","journal-title":"Vector-Borne and Zoonotic Diseases"},{"key":"ref581","doi-asserted-by":"crossref","first-page":"309","DOI":"10.5326\/15473317-34-4-309","article-title":"Surgical and chemotherapeutiv treatment of alveolar echinococcosis in a dog","volume":"34","year":"1998","journal-title":"Journal of American Animal Hospital Association"},{"key":"ref121","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1186\/1746-6148-9-159","article-title":"Unusual presentation of alveolar echinococcosis as prostatic ad paraprostatic cyst in a dog","volume":"9","year":"2013","journal-title":"BMC Veterinary Research"},{"key":"ref241","first-page":"171","article-title":"A case of alveolar echinococcosis in a horse","volume":"32","year":"1984","journal-title":"Japanese Journal of Veterinary Research"},{"key":"ref401","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/j.parint.2013.08.011","article-title":"Echinococcus multilocularis infection of a ring-tailed lemur (Lemur catta) and a nutria (Myocastor coypus) in a French zoo","volume":"62","year":"2013","journal-title":"Parasitology International"},{"key":"ref341","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.vetpar.2006.05.026","article-title":"Serological diagnosis of canine alveolar echinococcosis","volume":"141","year":"2006","journal-title":"Veterinary Parasitology"},{"key":"ref161","first-page":"123","article-title":"A case of alveolar hydatid disease in a dog: domestic animals as rare incidental intermediate hosts for Echinococcus multilocularis","volume":"149","year":"2007","journal-title":"Schweizer Archiv Fur Tierheilkunde"},{"key":"ref841","first-page":"828","article-title":"A dog with alveolar echinococcosis: the larval stage of the fox tapeworm","volume":"132","year":"2007","journal-title":"Tijdschrift Voor Diergeneeskunde"},{"key":"ref111","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1186\/s13071-017-2369-0","article-title":"Dogs as victims of their own worms: Serological diagnosis of canine alveolar echinococcosis","volume":"10","year":"2017","journal-title":"Parasites & Vectors"},{"key":"ref211","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1136\/vr.141.2.49","article-title":"Larval Echinococcus multilocularis infection in a dog","volume":"141","year":"1997","journal-title":"Veterinary Record"},{"key":"ref851","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1186\/s13071-017-2172-y","article-title":"Genetic variation of mitochondrial genes among Echinococcus multilocularis isolates collected in western China","volume":"10","year":"2017","journal-title":"Parasites & Vectors"},{"key":"ref191","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/bs.apar.2016.09.006","article-title":"The Echinococcoses: Diagnosis, Clinical Management and Burden of Disease","volume":"96","year":"2017","journal-title":"Advances in Parasitology"},{"key":"ref271","first-page":"59","volume-title":"Alveolar echinococcosis: Strategy for eradication of alveolar echinococcosis of the liver.","year":"1996"},{"key":"ref321","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1016\/j.ijpara.2007.11.008","article-title":"Development of a new PCR protocol for the detection of species and genotypes (strains) of Echinococcus in formalin-fixed, paraffin-embedded tissues","volume":"38","year":"2008","journal-title":"International Journal for Parasitology"},{"key":"ref731","first-page":"870","article-title":"Alveolar hydatid disease (Echinococcus multilocularis) in the liver of a Canadian dog in British Columbia, a newly endemic region","volume":"536","year":"2012","journal-title":"Canadian Veterinary Journal"},{"key":"ref561","first-page":"267","article-title":"Pulmonary Echinococcus multilocularis metastasis in a dog","volume":"56","year":"2015","journal-title":"Canadian Veterinary Journal"},{"key":"ref601","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/j.vetpar.2011.09.022","article-title":"The first detection of Echinococcus multilocularis in slaughtered pigs in Poland","volume":"185","year":"2012","journal-title":"Veterinary Parasitology"},{"key":"ref501","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/S0304-4017(01)00424-1","article-title":"Veterinary aspects of alveolar echinococcosis \u2013 a zoonosis of public health significance","volume":"98","year":"2001","journal-title":"Veterinary Parasitology"},{"key":"ref171","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/j.vetpar.2011.09.022","article-title":"The first detection of Echinococcus multilocularis in slaughtered pigs in Poland","volume":"185","year":"2012","journal-title":"Veterinary Parasitology"},{"key":"ref521","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1016\/j.vetpar.2008.07.030","article-title":"Echinococcus multilocularis infections in domestic dogs and cats from Germany and other European countries","volume":"157","year":"2008","journal-title":"Veterinary Parasitology"},{"key":"ref301","first-page":"870","article-title":"Alveolar hydatid disease (Echinococcus multilocularis) in the liver of a Canadian dog in British Columbia, a newly endemic region","volume":"536","year":"2012","journal-title":"Canadian Veterinary Journal"},{"key":"ref491","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1136\/vr.103470","article-title":"Clinical presentation, diagnosis, therapy and outcome of alveolar echinococcosis in dogs","volume":"177","year":"2015","journal-title":"Veterinary Record"},{"key":"ref621","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/bs.apar.2016.09.006","article-title":"The Echinococcoses: Diagnosis, Clinical Management and Burden of Disease","volume":"96","year":"2017","journal-title":"Advances in Parasitology"},{"key":"ref661","doi-asserted-by":"crossref","first-page":"155","DOI":"10.2478\/s11687-011-0023-5","article-title":"Fox tapeworm (Echinococcus multilocularis) in Slovakia \u2013 summarizing the long-term monitoring","volume":"48","year":"2011","journal-title":"Helminthologia"},{"key":"ref101","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1128\/CMR.17.1.107-135.2004","article-title":"Biological, epidemiological, and clinical aspects of echinococcosis, a zoonosis of increasing concern","volume":"17","year":"2004","journal-title":"Clinical Microbiology Reviews"},{"key":"ref181","first-page":"018","article-title":"First detection of Echinococcus multilocularis in dogs in highly endemic area of Poland","volume":"63","year":"2016","journal-title":"Folia Parasitologica"},{"key":"ref81","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1007\/s15010-016-0918-7","article-title":"Autochtonous human alveolar echinococcosis in a Hungarian patient","volume":"45","year":"2017","journal-title":"Infection"}],"container-title":["Acta Parasitologica"],"original-title":[],"link":[{"URL":"http:\/\/www.degruyter.com\/view\/j\/ap.2018.63.issue-3\/ap-2018-0058\/ap-2018-0058.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.degruyter.com\/view\/j\/ap.2018.63.issue-3\/ap-2018-0058\/ap-2018-0058.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,27]],"date-time":"2022-08-27T10:29:48Z","timestamp":1661596188000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.degruyter.com\/view\/j\/ap.2018.63.issue-3\/ap-2018-0058\/ap-2018-0058.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9,25]]},"references-count":84,"journal-issue":{"issue":"3"},"URL":"https:\/\/doi.org\/10.1515\/ap-2018-0058","relation":{},"ISSN":["1896-1851","1230-2821"],"issn-type":[{"value":"1896-1851","type":"electronic"},{"value":"1230-2821","type":"print"}],"subject":[],"published":{"date-parts":[[2018,9,25]]}}}