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Our results indicate that, independently of the latency program established in the host cells, induction of the EBV lytic cycle reduces the expression of the proteasomal components \u03b25, \u03b21 and \u03b22i, whereas it increases that of \u03b22, \u03b21i, PA28\u03b1 and PA28\u03b2. The modulation of the composition and enzymatic activities of the proteolytic complex are indicative of a less efficient generation of viral immunoepitopes.<\/jats:p>","DOI":"10.1515\/bc.2010.107","type":"journal-article","created":{"date-parts":[[2010,6,11]],"date-time":"2010-06-11T10:20:16Z","timestamp":1276251616000},"source":"Crossref","is-referenced-by-count":4,"title":["Epstein-Barr virus lytic cycle activation alters proteasome subunit expression in Burkitt's lymphoma cells"],"prefix":"10.1515","volume":"391","author":[{"given":"Alessandra","family":"De Leo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giulia","family":"Matusali","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Arena","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Livia","family":"Di Renzo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena","family":"Mattia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","reference":[{"key":"p_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1044-579X(02)00101-3"},{"key":"p_2","doi-asserted-by":"crossref","first-page":"3281","DOI":"10.4049\/jimmunol.160.7.3281","volume":"160","author":"Frisan T.","year":"1998","journal-title":"J. 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