{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T09:52:55Z","timestamp":1788601975339,"version":"build-2803163510"},"reference-count":32,"publisher":"Walter de Gruyter GmbH","issue":"1","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,1,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Intestinal sulfate-reducing bacteria are often isolated from patients with inflammatory bowel disease, including ulcerative colitis, and can be involved in the development of gut inflammation. A comparison of the metabolism of intestinal sulfate-reducing bacteria isolated from individuals with colitis and healthy controls using statistical analysis has never been studied and described before. The aim of our research was to evaluate the parameters of dissimilatory sulfate reduction in\n                    <jats:italic>Desulfovibrio<\/jats:italic>\n                    species that were isolated from the feces of healthy objects and individuals with colitis. Principal component analysis indicates that the strains that were isolated from individuals with colitis grouped in the same cluster by biomass accumulation and sulfide production, same as the strains isolated from healthy individuals. Sulfate and lactate consumption measured over time showed negative correlation (Pearson correlations,\n                    <jats:italic>p<\/jats:italic>\n                    &lt;0.01), healthy: -0.760; colitis: -0.770; healthy: -0.828; colitis: -0.847, respectively. The calculated linear regression (R\n                    <jats:sup>2<\/jats:sup>\n                    ) was lower in biomass accumulation and hydrogen sulfide production, 0.531; 0.625 respectively. Thus, biomass accumulation and sulfide production, together with measured kinetic parameters play an important factor in bowel inflammation, including ulcerative colitis. Additionally, acetate production can also synergize with H\n                    <jats:sub>2<\/jats:sub>\n                    S, while sulfate consumption and lactate oxidation likely represent minor factors in bowel disease.\n                  <\/jats:p>","DOI":"10.1515\/biol-2018-0057","type":"journal-article","created":{"date-parts":[[2019,1,9]],"date-time":"2019-01-09T04:00:45Z","timestamp":1547006445000},"page":"481-488","source":"Crossref","is-referenced-by-count":63,"title":["Analysis of physiological parameters of\n                    <i>Desulfovibrio<\/i>\n                    strains from individuals with colitis"],"prefix":"10.1515","volume":"13","author":[{"given":"Ivan","family":"Kushkevych","sequence":"first","affiliation":[{"name":"Department of Experimental Biology , Faculty of Science , Masaryk University , Kamenice 753\/5, 625 00 Brno , Czech Republic"},{"name":"Department of Human Pharmacology and Toxicology , Faculty of Pharmacy , University of Veterinary and Pharmaceutical Sciences , Brno , Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dani","family":"Dordevi\u0107","sequence":"additional","affiliation":[{"name":"Department of Plant Origin Foodstuffs Hygiene and Technology , Faculty of Veterinary Hygiene and Ecology , University of Veterinary and Pharmaceutical Sciences Brno , Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Koll\u00e1r","sequence":"additional","affiliation":[{"name":"Department of Human Pharmacology and Toxicology , Faculty of Pharmacy , University of Veterinary and Pharmaceutical Sciences , Brno , Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2019,1,4]]},"reference":[{"key":"2025122007345199579_j_biol-2018-0057_ref_001_w2aab2b8d422b1b7b1ab2b2b1Aa","doi-asserted-by":"crossref","unstructured":"Hirano A, Umeno J, Okamoto Y, Shibata H, Ogura Y, Moriyama T, et al. 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