{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T17:10:20Z","timestamp":1781629820682,"version":"3.54.5"},"reference-count":32,"publisher":"Walter de Gruyter GmbH","issue":"1","license":[{"start":{"date-parts":[[2020,4,26]],"date-time":"2020-04-26T00:00:00Z","timestamp":1587859200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,4,26]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Brunner\u2019s gland adenoma is a rare benign tumor arising from\n                  Brunner\u2019s glands. It is mostly small in size, and patients with this tumor\n                  are asymptomatic.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case presentation<\/jats:title><jats:p>We report the case of a 63-year-old woman with upper gastrointestinal obstruction\n                  for almost 10 years, who was pathologically diagnosed with large Brunner\u2019s\n                  gland adenoma of the duodenum. Postoperatively, no sign of recurrence has been\n                  noted until now.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study may help clinicians to understand and provide a more accurate diagnosis\n                  of Brunner\u2019s gland adenoma.<\/jats:p><\/jats:sec>","DOI":"10.1515\/biol-2020-0029","type":"journal-article","created":{"date-parts":[[2020,5,14]],"date-time":"2020-05-14T09:29:46Z","timestamp":1589448586000},"page":"237-240","source":"Crossref","is-referenced-by-count":2,"title":["Large Brunner\u2019s gland adenoma of the duodenum for almost 10 years"],"prefix":"10.1515","volume":"15","author":[{"given":"Bo","family":"Yang","sequence":"first","affiliation":[{"name":"Department of General Surgery, Fuling Central Hospital of Chongqing City, Chongqing, 408000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ke","family":"Li","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Fuling Central Hospital of Chongqing City, Chongqing, 408000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Runlan","family":"Luo","sequence":"additional","affiliation":[{"name":"Department of Ultrasound, Fuling Central Hospital of Chongqing City, Chongqing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zuming","family":"Xiong","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Fuling Central Hospital of Chongqing City, Chongqing, 408000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lianwei","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Fuling Central Hospital of Chongqing City, Chongqing, 408000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinming","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Fuling Central Hospital of Chongqing City, Chongqing, 408000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dengyang","family":"Fang","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Fuling Central Hospital of Chongqing City, Chongqing, 408000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","reference":[{"key":"ref141","first-page":"413","article-title":"Giant Brunner\u2019s gland adenoma of the duodenal bulb presenting                   with ampullary and duodenal obstruction mimicking pancreatic                   malignancy","volume":"12","year":"2011","journal-title":"JOP"},{"key":"ref191","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1007\/BF01658970","article-title":"Primary jejunoileal tumors: a review of 45 cases","volume":"15","year":"1991","journal-title":"World J Surg"},{"key":"ref101","first-page":"290","article-title":"Brunner\u2019s gland hamartomas: clinical presentation and                   pathological features of 27 cases","volume":"90","year":"1995","journal-title":"Am J Gastroenterol"},{"key":"ref301","first-page":"413","article-title":"Giant Brunner\u2019s gland adenoma of the duodenal bulb presenting                   with ampullary and duodenal obstruction mimicking pancreatic                   malignancy","volume":"12","year":"2011","journal-title":"JOP"},{"key":"ref111","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1007\/BF02773877","article-title":"Thickness of Brunner\u2019s glands and its clinical significance in                   peptic ulcer diseases","volume":"24","year":"1989","journal-title":"Gastroenterol Jpn"},{"key":"ref231","doi-asserted-by":"crossref","first-page":"1966","DOI":"10.3748\/wjg.v12.i12.1966","article-title":"Large Brunner\u2019s gland adenoma: case report and literature                   review","volume":"12","year":"2006","journal-title":"World J 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Surg"},{"key":"ref01","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1007\/s005350050029","article-title":"Brunner\u2019s gland adenoma with a focus of p53-positive atypical                   glands","volume":"35","year":"2000","journal-title":"J Gastroenterol"},{"key":"ref291","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1155\/2006\/806926","article-title":"Acute pancreatitis and upper gastrointestinal bleeding as presenting                   symptoms of duodenal Brunner\u2019s gland hamartoma","volume":"20","year":"2006","journal-title":"Can J Gastroenterol"},{"key":"ref61","first-page":"81","article-title":"Diffuse nodular hyperplasia of Brunner\u2019s gland presenting as                   upper gastrointestinal haemorrhage","volume":"49","year":"2008","journal-title":"Singap Med J"},{"key":"ref71","doi-asserted-by":"crossref","first-page":"1966","DOI":"10.3748\/wjg.v12.i12.1966","article-title":"Large Brunner\u2019s gland adenoma: case report and literature  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Brunner\u2019s gland hamartoma","volume":"20","year":"2006","journal-title":"Can J Gastroenterol"},{"key":"ref311","first-page":"78","article-title":"A case of Brunner\u2019s gland adenoma mimicking tumors induced from                   head of the pancreas","volume":"29","year":"2018","journal-title":"Pan Afr Med J"}],"container-title":["Open Life 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