{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T12:58:58Z","timestamp":1780491538988,"version":"3.54.1"},"reference-count":10,"publisher":"Walter de Gruyter GmbH","issue":"1","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,8,17]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Nasopharyngeal tuberculosis is a rare disease. Even in areas where tuberculosis is endemic, its incidence is also extremely low. Here, we will report a rare case of nasopharyngeal tuberculosis. A 29-year-old male patient presented with a 2-month history of sore throat, nasal congestion, dysphagia, and low-grade fever. Thickened mucosa in the posterior wall of the nasopharynx was shown from nasopharyngoscopy, covered with a thick, yellowish, purulent secretion that was not easily removed. Computed tomography of the nasopharynx showed thickening of the mucosa in the right and left bilateral walls and the posterior wall with indistinct margins. Histopathological examination diagnosed nasopharyngeal tuberculosis granuloma. Nasopharyngeal tuberculosis is rare and has atypical symptoms. When a new organism appears in the nasopharynx, it should be differentiated from tuberculosis, autoimmune diseases, and tumors, and a tissue biopsy of the new organism should be performed to make a final diagnosis based on histopathology.<\/jats:p>","DOI":"10.1515\/biol-2022-0077","type":"journal-article","created":{"date-parts":[[2022,8,17]],"date-time":"2022-08-17T12:55:01Z","timestamp":1660740901000},"page":"973-977","source":"Crossref","is-referenced-by-count":3,"title":["Nasopharyngeal tuberculosis: A case report"],"prefix":"10.1515","volume":"17","author":[{"given":"Yang","family":"Yang","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology Head and Neck Surgery, Baoshan People\u2019s Hospital , Baoshan 678000 , Yunnan Province , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan","family":"Fang","sequence":"additional","affiliation":[{"name":"Department of Organ Transplantation, The First Affiliated Hospital of Kunming Medical University , 295 Xichang Road , Kunming 650032 , Yunnan Province , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"GuoNing","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Head and Neck Surgery, Baoshan People\u2019s Hospital , Baoshan 678000 , Yunnan Province , China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2022,8,17]]},"reference":[{"key":"2022120618363471545_j_biol-2022-0077_ref_001","doi-asserted-by":"crossref","unstructured":"Seki M, Choi H, Kim K, Whang J, Sung J, Mitarai S. Tuberculosis: A persistent unpleasant neighbour of humans. J Infect Public Health. 2021;14(4):508\u201313.","DOI":"10.1016\/j.jiph.2021.01.005"},{"key":"2022120618363471545_j_biol-2022-0077_ref_002","doi-asserted-by":"crossref","unstructured":"Min H, Kim K. Primary nasopharyngeal tuberculosis: a case report focused on nasopharyngoscopic features and CT findings. Ear Nose Throat J. 2021;100:949\u201352S.","DOI":"10.1177\/0145561320931951"},{"key":"2022120618363471545_j_biol-2022-0077_ref_003","doi-asserted-by":"crossref","unstructured":"Darouassi Y, Chihani M, Elktaibi A, Touati M, Nadour K, Benjelloun A, et al. Association of laryngeal and nasopharyngeal tuberculosis: a case report. J Med Case Rep. 2015;9:2.","DOI":"10.1186\/1752-1947-9-2"},{"key":"2022120618363471545_j_biol-2022-0077_ref_004","doi-asserted-by":"crossref","unstructured":"Sawada N, Inokuchi G, Komatsu H, Kurakawa S, Tada K, Kumoi K. Nasopharyngeal tuberculosis. J Infect Chemotherapy Off J Jpn Soc Chemotherapy. 2013;19(6):1158\u201360.","DOI":"10.1007\/s10156-013-0574-0"},{"key":"2022120618363471545_j_biol-2022-0077_ref_005","doi-asserted-by":"crossref","unstructured":"Nakao Y, Shibata R, Murohara T, Tanigawa T. Primary nasopharyngeal tuberculosis: a case report. BMC Infect Dis. 2016;16:121.","DOI":"10.1186\/s12879-016-1449-7"},{"key":"2022120618363471545_j_biol-2022-0077_ref_006","doi-asserted-by":"crossref","unstructured":"\u00d6zcan C, Vayso\u011flu Y, G\u00fc\u00e7l\u00fct\u00fcrk T, Apa D, G\u00f6r\u00fcr K. Nasopharyngeal tuberculosis presenting as massive cervical lymphadenopathy and hearing loss. J Craniofacial Surg. 2012;23(4):e341\u20133.","DOI":"10.1097\/SCS.0b013e3182564d3f"},{"key":"2022120618363471545_j_biol-2022-0077_ref_007","doi-asserted-by":"crossref","unstructured":"Chao Y, Li J, Gong Z, Li C, Ye M, Hong Q, et al. Rapid discrimination between tuberculosis and sarcoidosis using next-generation sequencing. Int J Infect Diseases IJID: Off Publ Int Soc Infect Dis. 2021;108:129\u201336.","DOI":"10.1016\/j.ijid.2021.05.028"},{"key":"2022120618363471545_j_biol-2022-0077_ref_008","unstructured":"Vr\u00eenceanu D, Dorob\u0103\u0163 BC, Sajin M, Mogoant\u0103 CA, Opri\u015fcan IC, H\u00eencu MC, et al. Cystic lymphangioma of nasopharynx in a 54-year-old man\u2009\u2013\u2009case report. A new histogenetic hypothesis. Romanian J Morphol Embryol = Rev Roumaine de Morphol Embryol. 2018;59(2):577\u201384."},{"key":"2022120618363471545_j_biol-2022-0077_ref_009","doi-asserted-by":"crossref","unstructured":"Sebastian S, Singhal A, Sharma A, Doloi P. Tuberculous otitis media \u2013 series of 10 cases. J Otolo. 2020;15(3):95\u20138.","DOI":"10.1016\/j.joto.2019.12.001"},{"key":"2022120618363471545_j_biol-2022-0077_ref_010","doi-asserted-by":"crossref","unstructured":"Min HJ, Kim CH. Nasal or nasopharyngeal tuberculosis should be considered in the initial diagnosis of sino-nasal inflammatory diseases. Yonsei Med J. 2017;58(2):471\u20132.","DOI":"10.3349\/ymj.2017.58.2.471"}],"container-title":["Open Life Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.degruyter.com\/document\/doi\/10.1515\/biol-2022-0077\/xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.degruyter.com\/document\/doi\/10.1515\/biol-2022-0077\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,6]],"date-time":"2022-12-06T22:25:58Z","timestamp":1670365558000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.degruyter.com\/document\/doi\/10.1515\/biol-2022-0077\/html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1,1]]},"references-count":10,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2022,7,16]]},"published-print":{"date-parts":[[2022,7,16]]}},"alternative-id":["10.1515\/biol-2022-0077"],"URL":"https:\/\/doi.org\/10.1515\/biol-2022-0077","relation":{},"ISSN":["2391-5412"],"issn-type":[{"value":"2391-5412","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,1,1]]}}}