{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,21]],"date-time":"2025-12-21T23:46:32Z","timestamp":1766360792883,"version":"3.48.0"},"reference-count":10,"publisher":"Walter de Gruyter GmbH","issue":"1","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,5,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Synovial sarcoma, a mesenchymal spindle cell malignancy commonly seen in young and middle-aged adults, typically occurs in the soft tissues around the major joints of the extremities, with some reports of occurrences outside the joints. However, primary pulmonary cases are rare. This study reports a 52-year-old female patient who was admitted due to coughing and recurrent haemoptysis and was ultimately diagnosed with primary pulmonary synovial sarcoma (PPSS) through surgery and pathology after a series of examinations, including computed tomography scans and bronchoscopy. The tumour was located at the orifice of the dorsal segment of the right lower lobe, and she underwent thoracoscopic right lower lobectomy + lymphadenectomy. After 1 year of follow-up, the patient was in good general condition, without discomfort or signs of tumour recurrence or metastasis. PPSS grows slowly and presents insidiously, with imaging findings lacking specificity, making it easily confused with lung cancer and other pulmonary tumours. In conclusion, this case provides physicians with insights into the clinical presentation, imaging features and necessary pathological and molecular biological tests for PPSS diagnosis, which is essential for improving diagnostic accuracy.<\/jats:p>","DOI":"10.1515\/biol-2025-1099","type":"journal-article","created":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T11:27:06Z","timestamp":1747222026000},"source":"Crossref","is-referenced-by-count":0,"title":["Primary pulmonary synovial sarcoma in the bronchial cavity: A case report"],"prefix":"10.1515","volume":"20","author":[{"given":"Jianliang","family":"Li","sequence":"first","affiliation":[{"name":"Department of Thoracic Surgery, The Second People\u2019s Hospital of Liaocheng , No. 306, Jiankang Street , Linqing City , Liaocheng, Shandong, 252600 , China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jia","family":"Tian","sequence":"additional","affiliation":[{"name":"Department of Pathology, The Second People\u2019s Hospital of Liaocheng , No. 306, Jiankang Street , Linqing City , Liaocheng, Shandong, 252600 , China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lin","family":"Rong","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, The Second People\u2019s Hospital of Liaocheng , No. 306, Jiankang Street , Linqing City , Liaocheng, Shandong, 252600 , China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junjie","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, The Second People\u2019s Hospital of Liaocheng , No. 306, Jiankang Street , Linqing City , Liaocheng, Shandong, 252600 , China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiuyue","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory, The Second People\u2019s Hospital of Liaocheng , No. 306, Jiankang Street , Linqing City , Liaocheng, Shandong, 252600 , China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","published-online":{"date-parts":[[2025,5,12]]},"reference":[{"key":"2025122123391373603_j_biol-2025-1099_ref_001","doi-asserted-by":"crossref","unstructured":"Sahin MF, Beyoglu MA, K\u0131ran MM, Yekeler E. A rare lung tumor: primary pulmonary synovial sarcoma. J Cancer Res Ther. 2023 Jan;19(Suppl 2):S901\u20133.","DOI":"10.4103\/jcrt.jcrt_1810_21"},{"key":"2025122123391373603_j_biol-2025-1099_ref_002","doi-asserted-by":"crossref","unstructured":"Corredor-Alonso GE, Lino-Silva LS, L\u00f3pez-Flores EY, Vel\u00e1squez-Tovar T, Dom\u00ednguez-Malag\u00f3n HR. Ultrastructural differences between synovial sarcoma and solitary fibrous tumor: comparative study in adult patients from the National Cancer Institute of Mexico. Ultrastruct Pathol. 2024 May;48(3):213\u201320.","DOI":"10.1080\/01913123.2024.2313742"},{"key":"2025122123391373603_j_biol-2025-1099_ref_003","doi-asserted-by":"crossref","unstructured":"Landuzzi L, Manara MC, Pazzaglia L, Lollini PL, Scotlandi K. Innovative breakthroughs for the treatment of advanced and metastatic synovial sarcoma. Cancers (Basel). 2023 Jul;15(15):3887.","DOI":"10.3390\/cancers15153887"},{"key":"2025122123391373603_j_biol-2025-1099_ref_004","doi-asserted-by":"crossref","unstructured":"Malik S, Ahluwalia C, Ahuja S. Primary pulmonary synovial sarcoma with extensive myxoid change masquerading as a lung hydatid cyst. Ann Thorac Surg Short Rep. 2024 Jun;2(4):669\u201371.","DOI":"10.1016\/j.atssr.2024.06.014"},{"key":"2025122123391373603_j_biol-2025-1099_ref_005","doi-asserted-by":"crossref","unstructured":"Yin T, Liu B, Xue J, Liu X, Shang S, Wang Y. Primary pulmonary monophasic synovial sarcoma initially presenting with bloody pleural effusion: a case report and literature review. Clin Case Rep. 2024 Apr;12(5):e8841.","DOI":"10.1002\/ccr3.8841"},{"key":"2025122123391373603_j_biol-2025-1099_ref_006","doi-asserted-by":"crossref","unstructured":"Li M, Huang M, Piao H, Wang Y, Liu K. Case report: primary cardiac synovial sarcoma invading the tricuspid valve in a pregnant woman. Front Cardiovasc Med. 2024 Oct;11:1437903. 10.3389\/fcvm.2024.1437903.","DOI":"10.3389\/fcvm.2024.1437903"},{"key":"2025122123391373603_j_biol-2025-1099_ref_007","doi-asserted-by":"crossref","unstructured":"Patton A, Oghumu S, Iwenofu OH. An SS18: NEDD4 cutaneous spindled and epithelioid sarcoma: an hitherto unclassified cutaneous sarcoma, resembling epithelioid sarcoma with aggressive clinical behavior. Genes Chromosomes Cancer. 2022 Oct;61(10):635\u201340.","DOI":"10.1002\/gcc.23071"},{"key":"2025122123391373603_j_biol-2025-1099_ref_008","doi-asserted-by":"crossref","unstructured":"Lasota J, Ch\u0142opek M, Kaczorowski M, Nat\u00e1lie K, Ry\u015b J, Kopczy\u0144ski J, et al. Utility of immunohistochemistry with antibodies to SS18-SSX chimeric proteins and C-terminus of SSX protein for synovial sarcoma differential diagnosis. Am J Surg Pathol. 2024 Jan;48(1):97\u2013105.","DOI":"10.1097\/PAS.0000000000002144"},{"key":"2025122123391373603_j_biol-2025-1099_ref_009","doi-asserted-by":"crossref","unstructured":"De Rocco S, Di Biasi J, Fantasia I, Tabacco S, Ricevuto E, Palumbo P, et al. Recurrent metastatic pulmonary synovial sarcoma during pregnancy: a case report and literature review. Diagnostics (Basel). 2024 Feb;14(4):424.","DOI":"10.3390\/diagnostics14040424"},{"key":"2025122123391373603_j_biol-2025-1099_ref_010","doi-asserted-by":"crossref","unstructured":"Kim CS, Cho HS, Lee OJ, Ahn SY, Yoo JY. Primary pulmonary synovial sarcoma with delayed diagnosis in a 69-year-old man: a case report. Medicine (Baltimore). 2023 Dec;102(51):e36620.","DOI":"10.1097\/MD.0000000000036620"}],"container-title":["Open Life Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.degruyterbrill.com\/document\/doi\/10.1515\/biol-2025-1099\/xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.degruyterbrill.com\/document\/doi\/10.1515\/biol-2025-1099\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,21]],"date-time":"2025-12-21T23:42:51Z","timestamp":1766360571000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.degruyterbrill.com\/document\/doi\/10.1515\/biol-2025-1099\/html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,1]]},"references-count":10,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,8,20]]},"published-print":{"date-parts":[[2025,8,20]]}},"alternative-id":["10.1515\/biol-2025-1099"],"URL":"https:\/\/doi.org\/10.1515\/biol-2025-1099","relation":{},"ISSN":["2391-5412"],"issn-type":[{"type":"electronic","value":"2391-5412"}],"subject":[],"published":{"date-parts":[[2025,1,1]]},"article-number":"20251099"}}