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We report a rare case of disseminated abscesses involving the liver, kidney and pararenal regions caused by\n                    <jats:italic>T.\u00a0denticola<\/jats:italic>\n                    , highlighting the role of next-generation sequencing (NGS) in diagnosis of uncommon abscesses. A 50-year-old female presented with a refractory lumbar abscess. Initial conventional cultures were negative, and empirical antibiotic therapy was ineffective. Abdominal computed tomography (CT) revealed liver abscess, and multiple renal and hepatic abscess. After the initial NGS analysis of the abscess fluid led to an inappropriate treatment adjustment, repeat NGS analysis of a liver biopsy specimen identified\n                    <jats:italic>T.\u00a0denticola.<\/jats:italic>\n                    The patient\u2019s condition was alleviated after the administration of a combined penicillin and doxycycline regimen and radical resection of the right hepatic lobe and kidney. This case confirms that\n                    <jats:italic>T.\u00a0denticola<\/jats:italic>\n                    can cause severe systemic infection. The integration of advanced diagnostic technologies and multidisciplinary collaboration is crucial in managing infections of unknown origin.\n                  <\/jats:p>","DOI":"10.1515\/biol-2025-1387","type":"journal-article","created":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T12:56:15Z","timestamp":1791809775000},"source":"Crossref","is-referenced-by-count":0,"title":["Disseminated abscesses from\n                    <i>Treponema denticola<\/i>\n                    diagnosed by next-generation sequencing: case report"],"prefix":"10.1515","volume":"21","author":[{"given":"Xuhong","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Nursing , The First Affiliated Hospital, Zhejiang University School of Medicine , Hangzhou 310000 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shanshan","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Nursing , The First Affiliated Hospital, Zhejiang University School of Medicine , Hangzhou 310000 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ye","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Nursing , The First Affiliated Hospital, Zhejiang University School of Medicine , Hangzhou 310000 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2026,10,12]]},"reference":[{"key":"2026101212561144824_j_biol-2025-1387_ref_001","doi-asserted-by":"crossref","unstructured":"Goetting-Minesky, MP, Godovikova, V, Saraithong, P, Rickard, AH, Crawley, BR, Agolli, SM, et al.. 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