{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T11:36:15Z","timestamp":1774611375685,"version":"3.50.1"},"reference-count":15,"publisher":"Walter de Gruyter GmbH","issue":"1","license":[{"start":{"date-parts":[[2017,6,1]],"date-time":"2017-06-01T00:00:00Z","timestamp":1496275200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,6,30]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Sirenomelia, also known as \u201cmermaid malformation\/syndrome,\u201d is a rare, serious congenital anomaly characterized by variable degrees of fusion of the lower limbs and associated with severe malformations of vertebral, genitourinary, cardiovascular system and single umbilical artery. The first pregnancy of a 25-year-old woman resulted in one twin born by Cesarian section at 32 weeks\u2019 gestation, who was referred to our hospital with cyanosis, a congenital anomaly and respiratory distress. On physical examination, there was no urogenital region and anal fissure and gender was indeterminate. The arms were in adduction and wrist in flexion position with four fingers on the right hand and two fingers on the left hand. There was a single lower extremity with a webbed single foot and two toes consistent with sirenomelia type IV radiologically. Abdominal ultrasonography showed urogenital system agenesis and echocardiography detected hypoplastic left heart. However, the patient died 4 hours after birth. The other twin was followed for 1 week for nutrition and respiratory support and was then discharged without any problems.<\/jats:p>","DOI":"10.1515\/bjmg-2017-0001","type":"journal-article","created":{"date-parts":[[2017,9,12]],"date-time":"2017-09-12T10:00:54Z","timestamp":1505210454000},"page":"91-94","source":"Crossref","is-referenced-by-count":11,"title":["Sirenomelia associated with hypoplastic left heart in a newborn"],"prefix":"10.1515","volume":"20","author":[{"given":"H","family":"Turgut","sequence":"first","affiliation":[{"name":"Division of Neonatology , Department of Pediatrics , Inonu University School of Medicine , Malatya , Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Ozdemir","sequence":"additional","affiliation":[{"name":"Division of Neonatology , Department of Pediatrics , Inonu University School of Medicine , Malatya , Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"IK","family":"Gokce","sequence":"additional","affiliation":[{"name":"Division of Neonatology , Department of Pediatrics , Inonu University School of Medicine , Malatya , Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Karakurt","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology , Inonu University School of Medicine , Malatya , Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Karadag","sequence":"additional","affiliation":[{"name":"Division of Neonatology , Department of Pediatrics , Inonu University School of Medicine , Malatya , Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","published-online":{"date-parts":[[2017,6,30]]},"reference":[{"key":"2021040720383999917_j_bjmg-2017-0001_ref_001_w2aab3b8b1b1b7b1ab2b1b1Aa","doi-asserted-by":"crossref","unstructured":"van Keirsbilck J, Cannie M, Robrechts C, de Ravel T, Dymarkowski S, van den Bosch T, et al. First trimester diagnosis of sirenomelia. Prenat Diagn. 2006; 26(8): 684-688.","DOI":"10.1002\/pd.1479"},{"key":"2021040720383999917_j_bjmg-2017-0001_ref_002_w2aab3b8b1b1b7b1ab2b1b2Aa","doi-asserted-by":"crossref","unstructured":"K\u00e4ll\u00e9n B, Castilla EE, Lancaster PA, Mutchinick O, Knudsen LB, Mart\u00ednez-Fr\u00edas ML, et al. The cyclops and the mermaid: An epidemiological study of two types of rare malformation. J Med Genet. 1992; 29(1): 30-35.","DOI":"10.1136\/jmg.29.1.30"},{"key":"2021040720383999917_j_bjmg-2017-0001_ref_003_w2aab3b8b1b1b7b1ab2b1b3Aa","doi-asserted-by":"crossref","unstructured":"Isik Kaygusuz E, Kurek EM, Sivrikoz ON, Cetiner H. Sirenomelia: A review of embryogenic theories and discussion of the differences from caudal regression syndrome. J Matern Fetal Neonatal Med. 2016; 29(6): 949-953.","DOI":"10.3109\/14767058.2015.1026254"},{"key":"2021040720383999917_j_bjmg-2017-0001_ref_004_w2aab3b8b1b1b7b1ab2b1b4Aa","unstructured":"Seidahmed MZ, Abdelbasit OB, Alhussein KA, Miqdad AM, Khalil MI, Salih MA. Sirenomelia and severe caudal regression syndrome. Saudi Med J. 2014; 35(1): 36-43."},{"key":"2021040720383999917_j_bjmg-2017-0001_ref_005_w2aab3b8b1b1b7b1ab2b1b5Aa","unstructured":"Sikandar R, Munim S. Sirenomelia, the mermaid syndrome: Case report and a brief review of literature. J Pak Med Assoc. 2009; 59(10): 721-723."},{"key":"2021040720383999917_j_bjmg-2017-0001_ref_006_w2aab3b8b1b1b7b1ab2b1b6Aa","unstructured":"Stocker JT, Heifetz SA. Sirenomelia. A morphological study of 33 cases and review of the literature. Perspect  Pediatr Pathol. 1987; 10(1): 7-50."},{"key":"2021040720383999917_j_bjmg-2017-0001_ref_007_w2aab3b8b1b1b7b1ab2b1b7Aa","unstructured":"Bermejo R, Cartagena F, Valiente M, M\u00e1rmol E, Aci\u00e9n P. Sirenomelia associated with truncus arteriosus. J Clin Case Rep. 2014; 4(359): 1-3."},{"key":"2021040720383999917_j_bjmg-2017-0001_ref_008_w2aab3b8b1b1b7b1ab2b1b8Aa","doi-asserted-by":"crossref","unstructured":"Drossou-Agakidou V1, Xatzisevastou-Loukidou C, Soubasi V, Kostopoulou E, Laporda A, Pantzaki A, et al. Rare manifestations of sirenomelia syndrome: A report of five cases. Am J Perinatol. 2004; 21(7): 395-401.","DOI":"10.1055\/s-2004-835314"},{"key":"2021040720383999917_j_bjmg-2017-0001_ref_009_w2aab3b8b1b1b7b1ab2b1b9Aa","doi-asserted-by":"crossref","unstructured":"Orioli IM, Amar E, Arteagavazquez J, Bakker MK, Bianca S, Botto LD, et al. Sirenomelia: An epidemiologic study in a large dataset from the International Clearinghouse of Birth Defects Surveillance and Research, and literature review. Am J Med Genet C Semin Med Genet. 2011; 157(4): 358-373.","DOI":"10.1002\/ajmg.c.30324"},{"key":"2021040720383999917_j_bjmg-2017-0001_ref_010_w2aab3b8b1b1b7b1ab2b1c10Aa","unstructured":"K\u0131r\u0131mi E, Peker E, Tuncer O, Akg\u00fcn C, Kurdoglu Z. Concurrence of sirenomelia and polydactyly: A case report. Anatol J Clin Invest. 2010; 4(1): 67-69."},{"key":"2021040720383999917_j_bjmg-2017-0001_ref_011_w2aab3b8b1b1b7b1ab2b1c11Aa","doi-asserted-by":"crossref","unstructured":"Chikkannaiah P, Mahadevan A, Gosavi M, Kangle R, Shankar SK. Sirenomelia with associated systemic anomalies. An autopsy pathologic illustration of a series of four cases. Pathol Res Pract. 2014; 210(7): 444-449.","DOI":"10.1016\/j.prp.2014.01.017"},{"key":"2021040720383999917_j_bjmg-2017-0001_ref_012_w2aab3b8b1b1b7b1ab2b1c12Aa","doi-asserted-by":"crossref","unstructured":"Moosa S, Lambie LA, Krause A. Sirenomelia: Four further cases with discussion of associated upper limb defects. Clin Dysmorphol. 2012; 21(3): 124-130.","DOI":"10.1097\/MCD.0b013e328354e51b"},{"key":"2021040720383999917_j_bjmg-2017-0001_ref_013_w2aab3b8b1b1b7b1ab2b1c13Aa","doi-asserted-by":"crossref","unstructured":"Castori M, Silvestri E, Cappellacci S, Binni F, Sforzolini GS, Grammatico P. Sirenomelia and VACTERL association in the offspring of a woman with diabetes. Am J Med Genet A. 2010; 152(7): 1803-1807.","DOI":"10.1002\/ajmg.a.33460"},{"key":"2021040720383999917_j_bjmg-2017-0001_ref_014_w2aab3b8b1b1b7b1ab2b1c14Aa","doi-asserted-by":"crossref","unstructured":"Duesterhoeft SM, Ernst LM, Siebert JR, Kapur RP. Five cases of caudal regression with an aberrant abdominal umbilical artery: Further support for a caudal regression-sirenomelia spectrum. Am J Med Genet A. 2007; 143(24): 3175-3184.","DOI":"10.1002\/ajmg.a.32028"},{"key":"2021040720383999917_j_bjmg-2017-0001_ref_015_w2aab3b8b1b1b7b1ab2b1c15Aa","doi-asserted-by":"crossref","unstructured":"Tonni G, Grisolia G. Sirenomelia: A review on embryogenic enviromental theories, novel threedimensional ultrasound imaging and first trimester diagnosis in a case of mosaic 69, XXX\/46, XX fetus. Arch Gynecol Obstet. 2013; 288(1): 3-11.","DOI":"10.1007\/s00404-013-2899-4"}],"container-title":["Balkan Journal of Medical Genetics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/content.sciendo.com\/view\/journals\/bjmg\/20\/1\/article-p91.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.sciendo.com\/article\/10.1515\/bjmg-2017-0001","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,8]],"date-time":"2021-04-08T03:36:19Z","timestamp":1617852979000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.sciendo.com\/article\/10.1515\/bjmg-2017-0001"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,6,1]]},"references-count":15,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2017,6,30]]},"published-print":{"date-parts":[[2017,6,30]]}},"alternative-id":["10.1515\/bjmg-2017-0001"],"URL":"https:\/\/doi.org\/10.1515\/bjmg-2017-0001","relation":{},"ISSN":["1311-0160"],"issn-type":[{"value":"1311-0160","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,6,1]]}}}