{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,5]],"date-time":"2025-12-05T19:29:38Z","timestamp":1764962978009,"version":"3.46.0"},"reference-count":90,"publisher":"Walter de Gruyter GmbH","issue":"1","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,10,25]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Couples with infertility issues have been assisted by\n                    <jats:italic>in vitro<\/jats:italic>\n                    fertilization reproduction technologies with high success rates of 50-80%. However, complications associated with ovarian stimulation remain, such as ovarian hyperstimulation. Oocyte quality is a significant factor impacting the outcome of\n                    <jats:italic>in vitro<\/jats:italic>\n                    fertilization procedures, but other processes are also critical for fertilization success. Increasing evidence points to aberrant inflammation as one of these critical processes reflected in molecular changes, including glycosylation of proteins. Here we report results from a MALDI-TOF-MS-based glycomic profiling of the total IgG and total proteome N-glycomes isolated from the follicular fluid obtained from patients undergoing fertilization through either (1) assisted reproduction by modified natural cycle or (2) controlled ovarian stimulation (GnRH antagonist, GnRH Ant) protocols. Significant inflammatory-related differences between analyzed N-glycomes were observed from samples and correlated with the ovarian stimulation protocol used in patients.\n                  <\/jats:p>","DOI":"10.1515\/bmc-2020-0015","type":"journal-article","created":{"date-parts":[[2020,11,3]],"date-time":"2020-11-03T10:05:11Z","timestamp":1604397911000},"page":"153-171","source":"Crossref","is-referenced-by-count":1,"title":["Mass spectrometry-based glycomic profiling of the total IgG and total proteome N-glycomes isolated from follicular fluid"],"prefix":"10.1515","volume":"11","author":[{"given":"Marko","family":"Klobu\u010dar","sequence":"first","affiliation":[{"name":"University of Rijeka, Department of Biotechnology, Centre for high-throughput technologies , Radmile Matej\u010di\u0107 2 , Rijeka , Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanja Devi\u0107","family":"Pavli\u0107","sequence":"additional","affiliation":[{"name":"University of Rijeka, Department of Medical Biology and Genetics, Faculty of Medicine , B. Branchetta 20 , Rijeka , Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iris","family":"Car","sequence":"additional","affiliation":[{"name":"University of Rijeka, Department of Biotechnology, Centre for high-throughput technologies , Radmile Matej\u010di\u0107 2 , Rijeka , Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neda Smiljan","family":"Severinski","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Clinical Hospital Centre Rijeka , Cambierieva 17\/5 , Rijeka , Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tamara Trami\u0161ak","family":"Milakovi\u0107","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Clinical Hospital Centre Rijeka , Cambierieva 17\/5 , Rijeka , Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"An\u0111elka Radoj\u010di\u0107","family":"Badovinac","sequence":"additional","affiliation":[{"name":"University of Rijeka, Department of Biotechnology, Centre for high-throughput technologies , Radmile Matej\u010di\u0107 2 , Rijeka , Croatia"},{"name":"University of Rijeka, Department of Medical Biology and Genetics, Faculty of Medicine , B. Branchetta 20 , Rijeka , Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandra Kraljevi\u0107","family":"Paveli\u0107","sequence":"additional","affiliation":[{"name":"University of Rijeka Faculty of Health Studies , Viktora Cara Emina 5 , Rijeka , Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","published-online":{"date-parts":[[2020,10,25]]},"reference":[{"key":"2025120518281418337_j_bmc-2020-0015_ref_001_w2aab3b7c80b1b6b1ab2b2b1Aa","doi-asserted-by":"crossref","unstructured":"Conti M, Franciosi F. Acquisition of oocyte competence to develop as an embryo: integrated nuclear and cytoplasmic events. Hum Reprod Update. 2018;24:245\u201366.","DOI":"10.1093\/humupd\/dmx040"},{"key":"2025120518281418337_j_bmc-2020-0015_ref_002_w2aab3b7c80b1b6b1ab2b2b2Aa","doi-asserted-by":"crossref","unstructured":"Santos-Ribeiro S, Mackens S, Racca A, Blockeel C. Towards complication-free assisted reproduction technology. 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