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Seventy-seven features were generated, regarding the texture, morphology and spatial distribution of nuclei. The probabilistic neural network (PNN) classifier, the exhaustive search feature selection method, the leave-one-out (LOO) and the bootstrap validation methods were used to design the PR system and to assess its precision. Optimal PR system design and evaluation were made feasible by the employment of graphics processing unit (GPU) and Compute Unified Device Architecture (CUDA) technologies. The accuracy of the PR-system was 93% and 88.6% when using the LOO and bootstrap validation methods, respectively. The proposed PR system for discriminating LSIL from HSIL of the cervix was designed to operate in a clinical environment, having the capability of being redesigned when new verified cases are added to its repository and when data from other medical centers are included, following similar biopsy material preparation procedures.<\/jats:p>","DOI":"10.1515\/bmt-2019-0040","type":"journal-article","created":{"date-parts":[[2019,11,20]],"date-time":"2019-11-20T09:02:16Z","timestamp":1574240536000},"page":"315-325","source":"Crossref","is-referenced-by-count":1,"title":["GPU-enabled design of an adaptable pattern recognition system for discriminating squamous intraepithelial lesions of the cervix"],"prefix":"10.1515","volume":"65","author":[{"given":"Christos","family":"Konstandinou","sequence":"first","affiliation":[{"name":"Department of Medical Physics, School of Health Sciences, Faculty of Medicine , University of Patras , Rio, Patras , Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0223-2502","authenticated-orcid":false,"given":"Spiros","family":"Kostopoulos","sequence":"additional","affiliation":[{"name":"Medical Image and Signal Processing Laboratory (MEDISP), Department of Biomedical Engineering , University of West Attica , Ag. Spyridonos Street , Egaleo, 122 43 Athens , Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dimitris","family":"Glotsos","sequence":"additional","affiliation":[{"name":"Medical Image and Signal Processing Laboratory (MEDISP), Department of Biomedical Engineering , University of West Attica , Athens , Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dimitra","family":"Pappa","sequence":"additional","affiliation":[{"name":"Department of Pathology , IASO Thessalias , Larissa , Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Panagiota","family":"Ravazoula","sequence":"additional","affiliation":[{"name":"Department of Pathology , University Hospital of Patras , Rio , Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George","family":"Michail","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology , University Hospital of Patras , Rio , Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ioannis","family":"Kalatzis","sequence":"additional","affiliation":[{"name":"Medical Image and Signal Processing Laboratory (MEDISP), Department of Biomedical Engineering , University of West Attica , Athens , Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pantelis","family":"Asvestas","sequence":"additional","affiliation":[{"name":"Medical Image and Signal Processing Laboratory (MEDISP), Department of Biomedical Engineering , University of West Attica , Athens , Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eleftherios","family":"Lavdas","sequence":"additional","affiliation":[{"name":"Department of Biomedical Sciences , University of West Attica , Athens , Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dionisis","family":"Cavouras","sequence":"additional","affiliation":[{"name":"Medical Image and Signal Processing Laboratory (MEDISP), Department of Biomedical Engineering , University of West Attica , Athens , Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George","family":"Sakellaropoulos","sequence":"additional","affiliation":[{"name":"Department of Medical Physics, School of Health Sciences, Faculty of Medicine , University of Patras , Rio, Patras , Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","published-online":{"date-parts":[[2019,11,20]]},"reference":[{"key":"2023033113225419338_j_bmt-2019-0040_ref_001_w2aab3b7c98b1b6b1ab2b2b1Aa","doi-asserted-by":"crossref","unstructured":"Kyrgiou M, Shafi M. 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