{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T05:05:40Z","timestamp":1783573540850,"version":"3.55.0"},"reference-count":56,"publisher":"Walter de Gruyter GmbH","issue":"4","license":[{"start":{"date-parts":[[2025,3,28]],"date-time":"2025-03-28T00:00:00Z","timestamp":1743120000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,8,26]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec id=\"j_bmt-2024-0445_abs_001\">\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>Helical plating is an established alternative to straight plating for humeral shaft fractures in order to prevent iatrogenic radial nerve damage. However, a previous biomechanical investigation indicated differences in fracture healing for helical plating due to a potential shift of interfragmentary movements compared to straight plating. Therefore, fracture healing simulations were performed to assess any differences in bone healing of helical vs. straight plating.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_bmt-2024-0445_abs_002\">\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>A systematic workflow for fracture healing analytics was created, covering essential steps of bone modelling, implant modelling, finite element modelling, fracture healing simulation and result analysis. Computational humerus models with an AO12C2 fracture and straight and helical osteosynthesis were created. An established fracture healing model was used to simulate callus formation over 112\u00a0days under physiological loading. The predicted tissue differentiation and interfragmentary movement (IFM) was tracked over the entire simulated healing course.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_bmt-2024-0445_abs_003\">\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Helical plating resulted in larger interfragmentary movements for compression and shear components, and in a greater proportion of near and far cortical movement. Vascularization and tissue formation were deferred, but cortical bridging was achieved.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_bmt-2024-0445_abs_004\">\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Helical plating resulted in slightly deferred bone healing due to larger interfragmentary shear movements. Considering the advantage of helical plating in clinical context, a slightly deferred bone healing is justifiable.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1515\/bmt-2024-0445","type":"journal-article","created":{"date-parts":[[2025,3,28]],"date-time":"2025-03-28T04:45:16Z","timestamp":1743137116000},"page":"337-346","source":"Crossref","is-referenced-by-count":2,"title":["Does helical plating for proximal humeral shaft fractures benefit bone healing? \u2013\u00a0an <i>in silico<\/i> analysis in fracture healing"],"prefix":"10.1515","volume":"70","author":[{"given":"Christian","family":"Halbauer","sequence":"first","affiliation":[{"name":"Department of Mechatronics and Medical Engineering, Biomechatronics Research Group , 138717 Ulm University of Applied Sciences , Ulm , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felix","family":"Capanni","sequence":"additional","affiliation":[{"name":"Department of Mechatronics and Medical Engineering, Biomechatronics Research Group , 138717 Ulm University of Applied Sciences , Ulm , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucas","family":"Engelhardt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Paech","sequence":"additional","affiliation":[{"name":"Department for Orthopedic and Trauma Surgery , University Medical Center Schleswig-Holstein , L\u00fcbeck , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Knop","sequence":"additional","affiliation":[{"name":"Department of Trauma Surgery and Orthopedics , Clinical Centre Stuttgart-Katharinenhospital , Stuttgart , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tobias","family":"Merkle","sequence":"additional","affiliation":[{"name":"Department of Trauma Surgery and Orthopedics , Clinical Centre Stuttgart-Katharinenhospital , Stuttgart , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomas","family":"Da Silva","sequence":"additional","affiliation":[{"name":"Department of Trauma Surgery and Orthopedics , Clinical Centre Stuttgart-Katharinenhospital , Stuttgart , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2025,3,28]]},"reference":[{"key":"2025080106581410431_j_bmt-2024-0445_ref_001","doi-asserted-by":"crossref","unstructured":"Da Silva, T, Rummel, F, Knop, C, Merkle, T. 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