{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,10]],"date-time":"2026-05-10T09:12:47Z","timestamp":1778404367734,"version":"3.51.4"},"reference-count":16,"publisher":"Walter de Gruyter GmbH","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Cardiac troponins have changed our understanding of myocardial infarction profoundly during the past 20 years. In fact release of cardiac troponin into the blood has become part of the definition of myocardial infarction. Diagnostics and treatment have taken these new insights into account. The novel high-sensitive assays for cardiac troponins that are available recently clearly constitute a significant further improvement of analytical performance. In addition, the still incomplete clinical data available indicate that these assays will also further improve patient care in many ways. In summary, cardiac troponins are a great example of the potential impact of analytical performance of diagnostic tests on patient care and patient outcome.<\/jats:p>","DOI":"10.1515\/cclm-2013-0604","type":"journal-article","created":{"date-parts":[[2013,8,19]],"date-time":"2013-08-19T15:36:55Z","timestamp":1376926615000},"source":"Crossref","is-referenced-by-count":6,"title":["Do we really need high-sensitive troponin immunoassays in the emergency department? Definitely, yes!"],"prefix":"10.1515","volume":"52","author":[{"given":"Karl J.","family":"Lackner","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","reference":[{"key":"ref01","first-page":"500","article-title":"revisited assay performance","author":"Tate","year":"2008","journal-title":"Clin Chem Lab Med"},{"key":"ref61","first-page":"306","article-title":"Serial changes in highly sensitive troponin I assays and early diagnosis of myocardial infarction","author":"Keller","year":"2011","journal-title":"Am Med Assoc"},{"key":"ref101","first-page":"51","article-title":"Laboratory diagnostics of myocardial infarction troponins and beyond","author":"Lackner","year":"2013","journal-title":"Clin Chem Lab Med"},{"key":"ref141","first-page":"54","article-title":"Apple PO for the IFCC Task Force on Clinical Applications of Cardiac","volume":"58","author":"Collinson","year":"2012","journal-title":"Biomarkers Clin Chem"},{"key":"ref121","first-page":"361","article-title":"Early diagnosis of myocardial infarction with sensitive cardiac troponin assays","author":"Reichlin","year":"2009","journal-title":"Engl J Med"},{"key":"ref211","first-page":"51","article-title":"Laboratory diagnostics of myocardial infarction troponins and beyond","author":"Lackner","year":"2013","journal-title":"Clin Chem Lab Med"},{"key":"ref171","first-page":"306","article-title":"Serial changes in highly sensitive troponin I assays and early diagnosis of myocardial infarction","author":"Keller","year":"2011","journal-title":"Am Med Assoc"},{"key":"ref31","first-page":"54","article-title":"Apple PO for the IFCC Task Force on Clinical Applications of Cardiac","volume":"58","author":"Collinson","year":"2012","journal-title":"Biomarkers Clin Chem"},{"key":"ref11","first-page":"361","article-title":"Early diagnosis of myocardial infarction with sensitive cardiac troponin assays","author":"Reichlin","year":"2009","journal-title":"Engl J Med"},{"key":"ref51","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1373\/clinchem.2009.134460","article-title":"High - sensitivity cardiac troponin T for early prediction of evolving non - ST - segment elevation myocardial infarction in patients with suspected acute coronary syndrome and negative troponin results on admission","author":"Giannitsis","year":"2010","journal-title":"Clin Chem"},{"key":"ref151","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1093\/clinchem\/42.1.140","article-title":"CA Current status and performance goals for serum thyrotropin assays","author":"Spencer","year":"1996","journal-title":"Clin Chem"},{"key":"ref131","first-page":"361","article-title":"Sensitive troponin I assay in early diagnosis of acute myocardial infarction","author":"Keller","year":"2009","journal-title":"Engl J Med"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1093\/clinchem\/42.1.140","article-title":"CA Current status and performance goals for serum thyrotropin assays","author":"Spencer","year":"1996","journal-title":"Clin Chem"},{"key":"ref111","first-page":"500","article-title":"revisited assay performance","author":"Tate","year":"2008","journal-title":"Clin Chem Lab Med"},{"key":"ref161","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1373\/clinchem.2009.134460","article-title":"High - sensitivity cardiac troponin T for early prediction of evolving non - ST - segment elevation myocardial infarction in patients with suspected acute coronary syndrome and negative troponin results on admission","author":"Giannitsis","year":"2010","journal-title":"Clin Chem"},{"key":"ref21","first-page":"361","article-title":"Sensitive troponin I assay in early diagnosis of acute myocardial infarction","author":"Keller","year":"2009","journal-title":"Engl J Med"}],"container-title":["Clinical Chemistry and Laboratory Medicine (CCLM)"],"original-title":[],"link":[{"URL":"https:\/\/www.degruyter.com\/document\/doi\/10.1515\/cclm-2013-0604\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,21]],"date-time":"2021-04-21T23:43:05Z","timestamp":1619048585000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.degruyter.com\/document\/doi\/10.1515\/cclm-2013-0604\/html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,1,1]]},"references-count":16,"journal-issue":{"issue":"2"},"URL":"https:\/\/doi.org\/10.1515\/cclm-2013-0604","relation":{},"ISSN":["1437-4331","1434-6621"],"issn-type":[{"value":"1437-4331","type":"electronic"},{"value":"1434-6621","type":"print"}],"subject":[],"published":{"date-parts":[[2014,1,1]]}}}