{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T07:53:54Z","timestamp":1777535634663,"version":"3.51.4"},"reference-count":46,"publisher":"Walter de Gruyter GmbH","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The objective of this study was to examine the diagnostic accuracy of high-sensitivity cardiac troponin T (hs-cTnT) for acute myocardial infarction (AMI) in patients with renal insufficiency, since this population has a high incidence of non-AMI elevations of hs-cTnT.<\/jats:p><jats:p>In this prospective study, we enrolled 2249 consecutive patients presenting with chest pain in the emergency department (ED), of whom 19.5% had an estimated glomerular filtration rate (eGFR)<\/jats:p><jats:p>Of the patients, 1108 (49.3%) were diagnosed as having AMI [321 with non-ST segment elevation myocardial infarction (NSTEMI)]. In patients whose final diagnosis was not AMI, there was a low but significant correlation between hs-cTnT and renal function [eGFR<\/jats:p><jats:p>Using a higher hs-cTnT cut-off value based on eGFR level is necessary for accurate diagnosis of AMI or NSTEMI in patients with renal insufficiency.<\/jats:p>","DOI":"10.1515\/cclm-2014-0715","type":"journal-article","created":{"date-parts":[[2015,4,11]],"date-time":"2015-04-11T01:57:05Z","timestamp":1428717425000},"source":"Crossref","is-referenced-by-count":13,"title":["Diagnosis of acute myocardial infarction in patients with renal insufficiency using high-sensitivity troponin T"],"prefix":"10.1515","volume":"53","author":[{"given":"Hualan","family":"Huang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuai","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weiqing","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hong","family":"Yi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiangyang","family":"Du","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xin","family":"Nie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong","family":"He","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haolan","family":"Song","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiang","family":"Miao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lanlan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guixing","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","reference":[{"key":"ref161","first-page":"111","article-title":"Influence of age and renal function on high - sensitivity cardiac troponin T diagnostic accuracy for the diagnosis of acute myocardial infarction","author":"Chenevier","year":"2013","journal-title":"Am J Cardiol"},{"key":"ref391","first-page":"111","article-title":"Influence of age and renal function on high - sensitivity cardiac troponin T diagnostic accuracy for the diagnosis of acute myocardial infarction","author":"Chenevier","year":"2013","journal-title":"Am J Cardiol"},{"key":"ref111","first-page":"130","article-title":"AS more accurate method to estimate glomerular filtration rate from serum creatinine : a new prediction equation Modification of Diet in Renal Disease Study Group","author":"Levey","year":"1999","journal-title":"Ann Intern Med"},{"key":"ref01","first-page":"121","article-title":"High - sensitivity troponin T concentrations in acute chest pain patients evaluated with cardiac computed tomography","author":"Januzzi","year":"2010","journal-title":"Circulation"},{"key":"ref401","first-page":"112","article-title":"Diagnostic performance of high - 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