{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T04:08:26Z","timestamp":1790136506772,"version":"4.0.1"},"reference-count":42,"publisher":"Walter de Gruyter GmbH","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The order of draw is regarded as a preanalytical issue to prevent carryover of additives during blood collection. Our objective was to prove the theory of ethylenediaminetetraacetic acid (EDTA) carryover for a closed vacuum system and the influence of EDTA on concentrations of selected biomarkers.<\/jats:p><jats:p>To test the carryover of EDTA, a blood collection with tripotassium EDTA (K<\/jats:p><jats:p>No EDTA contamination was detected in samples collected subsequent to a K<\/jats:p><jats:p>An EDTA carryover during blood collection using a closed vacuum system is highly unlikely. Even if carryover of EDTA whole blood occurs, an absolute volume larger than 10 \u03bcL would be necessary to alter test results. However, contamination of samples with preloaded pure K<\/jats:p>","DOI":"10.1515\/cclm-2014-0944","type":"journal-article","created":{"date-parts":[[2015,1,23]],"date-time":"2015-01-23T17:38:08Z","timestamp":1422034688000},"source":"Crossref","is-referenced-by-count":22,"title":["Relevance of EDTA carryover during blood collection"],"prefix":"10.1515","volume":"53","author":[{"given":"Janne","family":"Cadamuro","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas Klaus","family":"Felder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hannes","family":"Oberkofler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cornelia","family":"Mrazek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helmut","family":"Wiedemann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabeth","family":"Haschke-Becher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","reference":[{"key":"ref321","first-page":"32","article-title":"DA Case increased APTT due to the presence of heparin Lab","author":"Schaeffer","year":"1981","journal-title":"history World"},{"key":"ref01","first-page":"213","article-title":"Labormedizin versuch einer prognose","volume":"18","author":"Kruse","year":"2000","journal-title":"Lab Med"},{"key":"ref381","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1155\/2005\/428672","article-title":"Monitoring and endogenous metabolite biomarkers from serum with mass spectrometry","volume":"19","author":"Lowe","year":"2005","journal-title":"Spectrosc Int J"},{"key":"ref451","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1258\/000456307780480846","article-title":"analysis on the modular analyser","author":"Davidson","year":"2007","journal-title":"Ann Clin Biochem"},{"key":"ref231","first-page":"59","article-title":"survey of some pre - 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