{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T02:11:45Z","timestamp":1793239905493,"version":"4.5.0"},"reference-count":39,"publisher":"Walter de Gruyter GmbH","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,5,25]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The International Federation of Clinical Chemistry and Laboarator Medicine (IFCC) Committee on Clinical Applications of Cardiac Bio-Markers (C-CB) has provided evidence-based educational resources to aid and improve the understanding of important analytical and clinical aspects of cardiac biomarkers. The present IFCC C-CB educational report focuses on recommendations for appropriate use, analytical performance, and gaps in clinical studies related to the use of cardiac troponin (cTn) by point of care (POC) measurement, often referred to as a point of care testing (POCT). The use of high-sensitivity (hs)-cTn POC devices in accelerated diagnostic protocols used in emergency departments or outpatient clinics investigating acute coronary syndrome has the potential for improved efficacy, reduction of length of stay and reduced costs in the health care system. POCT workflow integration includes location of the instrument, assignment of collection and testing responsibility to (non-lab) staff, instrument maintenance, in-service and recurrent training, quality control, proficiency assessments, discrepant result trapping, and troubleshooting and inventory management.<\/jats:p>","DOI":"10.1515\/cclm-2022-1270","type":"journal-article","created":{"date-parts":[[2023,1,13]],"date-time":"2023-01-13T19:51:42Z","timestamp":1673639502000},"page":"989-998","source":"Crossref","is-referenced-by-count":39,"title":["Cardiac troponin measurement at the point of care: educational recommendations on analytical and clinical aspects by the IFCC Committee on Clinical Applications of Cardiac Bio-Markers (IFCC C-CB)"],"prefix":"10.1515","volume":"61","author":[{"given":"Paul","family":"Collinson","sequence":"first","affiliation":[{"name":"Departments of Clinical Blood Sciences and Cardiology , St George\u2019s University Hospitals NHS Foundation Trust , London , UK"},{"name":"St George\u2019s University of London , London , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7340-6736","authenticated-orcid":false,"given":"Kristin M.","family":"Aakre","sequence":"additional","affiliation":[{"name":"Department of Medical Biochemistry and Pharmacology and Department of Heart Disease , Haukeland University Hospital , Bergen , Norway"},{"name":"Department of Clinical Science , University of Bergen , Bergen , Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy","family":"Saenger","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine and Pathology , Hennepin Healthcare\/HCMC , Minneapolis , MN , USA"},{"name":"Department of Laboratory Medicine and Pathology , University of Minnesota , Minneapolis , MN , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rick","family":"Body","sequence":"additional","affiliation":[{"name":"Emergency Department , Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre , Manchester , UK"},{"name":"Division of Cardiovascular Sciences , The University of Manchester , Manchester , UK"},{"name":"Healthcare Sciences Department , Manchester Metropolitan University , Manchester , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ole","family":"Hammarsten","sequence":"additional","affiliation":[{"name":"Department of Clinical Chemistry and Transfusion Medicine , University of Gothenburg , Gothenburg , Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allan S.","family":"Jaffe","sequence":"additional","affiliation":[{"name":"Departments of Laboratory Medicine and Pathology and Cardiology , Mayo Clinic , Rochester , MN , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pete","family":"Kavsak","sequence":"additional","affiliation":[{"name":"Department of Pathology and Molecular Medicine , McMaster University , Hamilton , ON , Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Torbj\u00f8rn","family":"Omland","sequence":"additional","affiliation":[{"name":"Department of Cardiology , Akershus University Hospital , L\u00f8renskog , Norway"},{"name":"Institute of Clinical Medicine, University of Oslo , Oslo , Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jordi","family":"Ordonez-Lianos","sequence":"additional","affiliation":[{"name":"Servicio de Bioqu\u00edmica Cl\u00ednica , Institut d\u2019Investigacions Biom\u00e8diques Sant Pau , Barcelona , Spain"},{"name":"Departamento de Bioqu\u00edmica y Biolog\u00eda Molecular , Universidad Aut\u00f2noma de Barcelona , Barcelona , Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brad","family":"Karon","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine and Pathology , Mayo Clinic , Rochester , MN , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fred S.","family":"Apple","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine and Pathology , Hennepin Healthcare\/HCMC , Minneapolis , MN , USA"},{"name":"Department of Laboratory Medicine and Pathology , University of Minnesota , Minneapolis , MN , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2023,1,16]]},"reference":[{"key":"2023042108131329228_j_cclm-2022-1270_ref_001","doi-asserted-by":"crossref","unstructured":"Collet, JP, Thiele, H, Barbato, E, Barthelemy, O, Bauersachs, J, Bhatt, DL, et al.. 2020 ESC guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation. 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