{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T12:52:40Z","timestamp":1791377560189,"version":"4.3.2"},"reference-count":10,"publisher":"Walter de Gruyter GmbH","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"DOI":"10.1515\/cclm-2026-1061","type":"journal-article","created":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T11:55:58Z","timestamp":1791374158000},"source":"Crossref","is-referenced-by-count":0,"title":["Urine-derived light chain sequencing enables serum-based MRD monitoring in multiple myeloma"],"prefix":"10.1515","author":[{"given":"Luciano H.","family":"Di Stefano","sequence":"first","affiliation":[{"name":"SEBIA , Evry , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9057-8751","authenticated-orcid":false,"given":"Charissa","family":"Wijmands","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine , Radboudumc , Nijmegen , The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joannes F.M.","family":"Jacobs","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine , Radboudumc , Nijmegen , The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent","family":"Bonifay","sequence":"additional","affiliation":[{"name":"SEBIA , Evry , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline","family":"Roug\u00e9 Dubroc","sequence":"additional","affiliation":[{"name":"SEBIA , Evry , France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2026,10,8]]},"reference":[{"key":"2026100711554376770_j_cclm-2026-1061_ref_001","doi-asserted-by":"crossref","unstructured":"Dimopoulos, MA, Terpos, E, Boccadoro, M, Moreau, P, Mateos, MV, Zweegman, S, et al.. EHA-EMN evidence-based guidelines for diagnosis, treatment and follow-up of patients with multiple myeloma. Nat Rev Clin Oncol 2025;22:680\u2013700. https:\/\/doi.org\/10.1038\/s41571-025-01041-x.","DOI":"10.1038\/s41571-025-01041-x"},{"key":"2026100711554376770_j_cclm-2026-1061_ref_002","doi-asserted-by":"crossref","unstructured":"Jacobs, JFM, Turner, KA, Graziani, MS, Frinack, JL, Ettore, MW, Tate, JR, et al.. An international multi-center serum protein electrophoresis accuracy and M-protein isotyping study. Part II: limit of detection and follow-up of patients with small M-proteins. Clin Chem Lab Med 2020;58:547\u201359. https:\/\/doi.org\/10.1515\/cclm-2019-1105.","DOI":"10.1515\/cclm-2019-1105"},{"key":"2026100711554376770_j_cclm-2026-1061_ref_003","doi-asserted-by":"crossref","unstructured":"Kumar, S, Paiva, B, Anderson, KC, Durie, B, Landgren, O, Moreau, P, et al.. International myeloma working group consensus criteria for response and minimal residual disease assessment in multiple myeloma. Lancet Oncol 2016;17:e328\u201346. https:\/\/doi.org\/10.1016\/s1470-2045(16)30206-6.","DOI":"10.1016\/S1470-2045(16)30206-6"},{"key":"2026100711554376770_j_cclm-2026-1061_ref_004","doi-asserted-by":"crossref","unstructured":"Munshi, NC, Avet-Loiseau, H, Anderson, KC, Neri, P, Paiva, B, Samur, M, et al.. A large meta-analysis establishes the role of MRD negativity in long-term survival outcomes in patients with multiple myeloma. Blood Adv 2020;4:5988\u201399. https:\/\/doi.org\/10.1182\/bloodadvances.2020002827.","DOI":"10.1182\/bloodadvances.2020002827"},{"key":"2026100711554376770_j_cclm-2026-1061_ref_005","doi-asserted-by":"crossref","unstructured":"Langerhorst, P, Noori, S, Zajec, M, De Rijke, YB, Gloerich, J, van Gool, AJ, et al.. Multiple myeloma minimal residual disease detection: targeted mass spectrometry in blood vs next-generation sequencing in bone marrow. Clin Chem 2021;67:1689\u201398. https:\/\/doi.org\/10.1093\/clinchem\/hvab187.","DOI":"10.1093\/clinchem\/hvab187"},{"key":"2026100711554376770_j_cclm-2026-1061_ref_006","doi-asserted-by":"crossref","unstructured":"Noori, S, Wijnands, C, Langerhorst, P, Bonifay, V, Stingl, C, Touzeau, C, et al.. Dynamic monitoring of myeloma minimal residual disease with targeted mass spectrometry. Blood Cancer J 2023;13:30. https:\/\/doi.org\/10.1038\/s41408-023-00803-z.","DOI":"10.1038\/s41408-023-00803-z"},{"key":"2026100711554376770_j_cclm-2026-1061_ref_007","doi-asserted-by":"crossref","unstructured":"Wijnands, C, Noori, S, Donk, N, VanDuijn, MM, Jacobs, JFM. Advances in minimal residual disease monitoring in multiple myeloma. Crit Rev Clin Lab Sci 2023;60:518\u201334. https:\/\/doi.org\/10.1080\/10408363.2023.2209652.","DOI":"10.1080\/10408363.2023.2209652"},{"key":"2026100711554376770_j_cclm-2026-1061_ref_008","doi-asserted-by":"crossref","unstructured":"Noori, S, Zajec, M, Russcher, H, Tintu, AN, Broijl, A, Jacobs, JFM, et al.. Retrospective longitudinal monitoring of multiple myeloma patients by mass spectrometry using archived serum protein electrophoresis gels and de novo sequence analysis. HemaSphere 2022;6:e758. https:\/\/doi.org\/10.1097\/hs9.0000000000000758.","DOI":"10.1097\/HS9.0000000000000758"},{"key":"2026100711554376770_j_cclm-2026-1061_ref_009","doi-asserted-by":"crossref","unstructured":"Nevone, A, Sadeghi, A, Mazzini, G, Milani, P, Mangiacavalli, S, Caminito, S, et al.. Bone marrow-free sequencing of M protein genes: a liquid biopsy approach in monoclonal gammopathies. Blood 2024;144:6905\u20136. https:\/\/doi.org\/10.1182\/blood-2024-206861.","DOI":"10.1182\/blood-2024-206861"},{"key":"2026100711554376770_j_cclm-2026-1061_ref_010","doi-asserted-by":"crossref","unstructured":"Wijnands, C, Langerhorst, P, Noori, S, Keizer-Garritsen, J, Wessels, H, Gloerich, J, et al.. M-protein diagnostics in multiple myeloma patients using ultra-sensitive targeted mass spectrometry and an off-the-shelf calibrator. Clin Chem Lab Med 2023;62:540\u201350.","DOI":"10.1515\/cclm-2023-0781"}],"container-title":["Clinical Chemistry and Laboratory Medicine (CCLM)"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.degruyterbrill.com\/document\/doi\/10.1515\/cclm-2026-1061\/xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.degruyterbrill.com\/document\/doi\/10.1515\/cclm-2026-1061\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T11:56:03Z","timestamp":1791374163000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.degruyterbrill.com\/document\/doi\/10.1515\/cclm-2026-1061\/html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,8]]},"references-count":10,"alternative-id":["10.1515\/cclm-2026-1061"],"URL":"https:\/\/doi.org\/10.1515\/cclm-2026-1061","relation":{},"ISSN":["1434-6621","1437-4331"],"issn-type":[{"value":"1434-6621","type":"print"},{"value":"1437-4331","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,8]]}}}