{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T13:11:46Z","timestamp":1790082706552,"version":"4.0.1"},"reference-count":10,"publisher":"Walter de Gruyter GmbH","license":[{"start":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T00:00:00Z","timestamp":1790121600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"DOI":"10.1515\/cclm-2026-1330","type":"journal-article","created":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T12:55:42Z","timestamp":1790081742000},"source":"Crossref","is-referenced-by-count":0,"title":["Clinical utility of a dedicated vanishing twin analytical workflow in single-nucleotide variant-based non-invasive prenatal testing: a case report of resolving prolonged aneuploidy discordance"],"prefix":"10.1515","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0750-5824","authenticated-orcid":false,"given":"Changhee","family":"Ha","sequence":"first","affiliation":[{"name":"Department of Laboratory Medicine , Konkuk University School of Medicine , Seoul , Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3266-638X","authenticated-orcid":false,"given":"Hanah","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine , Konkuk University School of Medicine , Seoul , Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4429-9978","authenticated-orcid":false,"given":"Mina","family":"Hur","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine , Konkuk University School of Medicine , Seoul , Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1835-0116","authenticated-orcid":false,"given":"In-Sook","family":"Sohn","sequence":"additional","affiliation":[{"name":"Division of Maternal and Fetal Medicine, Department of Obstetrics and Gynecology , Konkuk University School of Medicine , Seoul , Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2026,9,23]]},"reference":[{"key":"2026092212553832722_j_cclm-2026-1330_ref_001","doi-asserted-by":"crossref","unstructured":"Rose, NC, Barrie, ES, Malinowski, J, Jenkins, GP, McClain, MR, LaGrave, D, et al.. Systematic evidence-based review: the application of noninvasive prenatal screening using cell-free DNA in general-risk pregnancies. Genet Med 2022;24:1379\u201391. https:\/\/doi.org\/10.1016\/j.gim.2022.03.019.","DOI":"10.1016\/j.gim.2022.03.019"},{"key":"2026092212553832722_j_cclm-2026-1330_ref_002","doi-asserted-by":"crossref","unstructured":"Ryan, A, Hunkapiller, N, Banjevic, M, Vankayalapati, N, Fong, N, Jinnett, KN, et al.. Validation of an enhanced version of a single-nucleotide polymorphism-based noninvasive prenatal test for detection of fetal aneuploidies. Fetal Diagn Ther 2016;40:219\u201323. https:\/\/doi.org\/10.1159\/000442931.","DOI":"10.1159\/000442931"},{"key":"2026092212553832722_j_cclm-2026-1330_ref_003","doi-asserted-by":"crossref","unstructured":"Gr\u00f6mminger, S, Yagmur, E, Erkan, S, Nagy, S, Schock, U, Bonnet, J, et al.. Fetal aneuploidy detection by cell-free DNA sequencing for multiple pregnancies and quality issues with vanishing twins. J\u00a0Clin Med 2014;3:679\u201392. https:\/\/doi.org\/10.3390\/jcm3030679.","DOI":"10.3390\/jcm3030679"},{"key":"2026092212553832722_j_cclm-2026-1330_ref_004","doi-asserted-by":"crossref","unstructured":"Niles, KM, Murji, A, Chitayat, D. Prolonged duration of persistent cell-free fetal DNA from vanishing twin. Ultrasound Obstet Gynecol 2018;52:547\u20138. https:\/\/doi.org\/10.1002\/uog.19004.","DOI":"10.1002\/uog.19004"},{"key":"2026092212553832722_j_cclm-2026-1330_ref_005","doi-asserted-by":"crossref","unstructured":"van Eekhout, JCA, Bekker, MN, Bax, CJ, Galjaard, RH. Non-invasive prenatal testing (NIPT) in twin pregnancies affected by early single fetal demise: a systematic review of NIPT and vanishing twins. Prenat Diagn 2023;43:829\u201337. https:\/\/doi.org\/10.1002\/pd.6388.","DOI":"10.1002\/pd.6388"},{"key":"2026092212553832722_j_cclm-2026-1330_ref_006","doi-asserted-by":"crossref","unstructured":"Norwitz, ER, McNeill, G, Kalyan, A, Rivers, E, Ahmed, E, Meng, L, et al.. Validation of a single-nucleotide polymorphism-based non-invasive prenatal test in twin gestations: determination of zygosity, individual fetal sex, and fetal aneuploidy. J\u00a0Clin Med 2019;8:937. https:\/\/doi.org\/10.3390\/jcm8070937.","DOI":"10.3390\/jcm8070937"},{"key":"2026092212553832722_j_cclm-2026-1330_ref_007","doi-asserted-by":"crossref","unstructured":"Curnow, KJ, Wilkins-Haug, L, Ryan, A, Kirkizlar, E, Stosic, M, Hall, MP, et al.. Detection of triploid, molar, and vanishing twin pregnancies by a single-nucleotide polymorphism-based noninvasive prenatal test. Am J Obstet Gynecol 2015;212:79 e1\u20139. https:\/\/doi.org\/10.1016\/j.ajog.2014.10.012.","DOI":"10.1016\/j.ajog.2014.10.012"},{"key":"2026092212553832722_j_cclm-2026-1330_ref_008","doi-asserted-by":"crossref","unstructured":"Zou, Y, Cui, L, Xue, M, Yan, J, Huang, M, Gao, M, et al.. Applications of noninvasive prenatal testing in vanishing twin syndrome pregnancies after treatment of assisted reproductive technology in a single center. Prenat Diagn 2021;41:226\u201333. https:\/\/doi.org\/10.1002\/pd.5836.","DOI":"10.1002\/pd.5836"},{"key":"2026092212553832722_j_cclm-2026-1330_ref_009","doi-asserted-by":"crossref","unstructured":"Balaguer, N, Mateu-Brull, E, Serra, V, Simon, C, Milan, M. Should vanishing twin pregnancies be systematically excluded from cell-free fetal DNA testing? Prenat Diagn 2021;41:1241\u20138. https:\/\/doi.org\/10.1002\/pd.5817.","DOI":"10.1002\/pd.5817"},{"key":"2026092212553832722_j_cclm-2026-1330_ref_010","doi-asserted-by":"crossref","unstructured":"Chen, CP. False positive non-invasive prenatal testing (NIPT) for trisomy 21 in vanishing twin syndrome pregnancy: a comparison of the NIPT results performed in different gestations. Taiwan J Obstet Gynecol 2023;62:929\u201330. https:\/\/doi.org\/10.1016\/j.tjog.2023.09.009.","DOI":"10.1016\/j.tjog.2023.09.009"}],"container-title":["Clinical Chemistry and Laboratory Medicine (CCLM)"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.degruyterbrill.com\/document\/doi\/10.1515\/cclm-2026-1330\/xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.degruyterbrill.com\/document\/doi\/10.1515\/cclm-2026-1330\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T12:55:47Z","timestamp":1790081747000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.degruyterbrill.com\/document\/doi\/10.1515\/cclm-2026-1330\/html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,23]]},"references-count":10,"alternative-id":["10.1515\/cclm-2026-1330"],"URL":"https:\/\/doi.org\/10.1515\/cclm-2026-1330","relation":{},"ISSN":["1434-6621","1437-4331"],"issn-type":[{"value":"1434-6621","type":"print"},{"value":"1437-4331","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,23]]}}}