{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T19:10:00Z","timestamp":1789931400230,"version":"4.0.1"},"reference-count":8,"publisher":"Walter de Gruyter GmbH","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>The European Union Safe Hearts Plan provides an opportunity to strengthen cardiovascular prevention, early detection, treatment, and monitoring across Europe. This EFLM position paper argues that laboratory medicine must be recognized as a central component of its implementation. Reliable and harmonized laboratory data underpin cardiovascular risk assessment, diagnosis, therapeutic guidance, longitudinal monitoring, and evaluation of population outcomes. Beyond the minimum health-check dataset, tiered and personalized pathways should integrate established biomarkers, specialist testing, and validated emerging technologies. EFLM proposes five priorities: embedding laboratory expertise in governance; translating core testing into personalized pathways; expanding equitable access through quality-assured decentralized models; linking testing to clinical action and value-based financing; and accelerating responsible innovation while strengthening professional capability. By connecting screening with diagnosis, treatment, and measurable outcomes, laboratory medicine can provide the quality, interpretation, and data infrastructure required to transform the Safe Hearts Plan from policy ambition into equitable cardiovascular health gains across Europe.<\/jats:p>","DOI":"10.1515\/cclm-2026-1439","type":"journal-article","created":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T18:55:48Z","timestamp":1789930548000},"source":"Crossref","is-referenced-by-count":0,"title":["Delivering the EU Safe Hearts Plan: the essential role of laboratory medicine in cardiovascular health"],"prefix":"10.1515","author":[{"given":"Damien","family":"Gruson","sequence":"first","affiliation":[{"name":"Department of Clinical Biochemistry , Cliniques Universitaires St-Luc and Universit\u00e9 Catholique de Louvain , Brussels , Belgium"},{"name":"P\u00f4le de recherche en Endocrinologie, Diab\u00e8te et Nutrition, Institut de Recherche Exp\u00e9rimentale et Clinique (IREC) , Cliniques Universitaires St-Luc and Universit\u00e9 Catholique de Louvain , Brussels , Belgium"},{"name":"European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) , Brussels , Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel","family":"Langlois","sequence":"additional","affiliation":[{"name":"European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) , Brussels , Belgium"},{"name":"Department of Laboratory Medicine , AZ St.-Jan Hospital , Bruges , Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1273-0604","authenticated-orcid":false,"given":"Abdurrahman","family":"Coskun","sequence":"additional","affiliation":[{"name":"European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) , Brussels , Belgium"},{"name":"Department of Medical Biochemistry, School of Medicine , Acibadem Mehmet Ali Ayd\u0131nlar, University , Istanbul , T\u00fcrkiye"},{"name":"Department of Medicine, Knappschaft Kliniken University Hospital Bochum , Ruhr University Bochum , Bochum , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6878-8645","authenticated-orcid":false,"given":"Snezana","family":"Jovicic","sequence":"additional","affiliation":[{"name":"European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) , Brussels , Belgium"},{"name":"Department for Medical Biochemistry, Faculty of Pharmacy , University of Belgrade , Belgrade , Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Stavelin","sequence":"additional","affiliation":[{"name":"European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) , Brussels , Belgium"},{"name":"The Norwegian Organization for Quality Improvement of Laboratory Examinations (NOKLUS) Haraldsplass Diaconess Hospital , Bergen , Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Bauer","sequence":"additional","affiliation":[{"name":"European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) , Brussels , Belgium"},{"name":"Institute for Lab. Diagnostics , Hygiene and Transfusion Medicine Klinikum Ludwigshafen am Rhein GmbH Ludwig-Maximilians University of Munich , Munich , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0270-1711","authenticated-orcid":false,"given":"Mario","family":"Plebani","sequence":"additional","affiliation":[{"name":"European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) , Brussels , Belgium"},{"name":"Department of Medicine-DIMED , University of Padova , Padova , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomas","family":"Zima","sequence":"additional","affiliation":[{"name":"European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) , Brussels , Belgium"},{"name":"Institute of Medical Biochemistry and Laboratory Diagnostics, First Faculty of Medicine , Charles University and General University Hospital in Prague , Prague , Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2026,9,21]]},"reference":[{"key":"2026092018554305631_j_cclm-2026-1439_ref_001","unstructured":"Communication on an EU cardiovascular health plan: the Safe Hearts Plan - public Health n.d. https:\/\/health.ec.europa.eu\/publications\/communication-eu-cardiovascular-health-plan-safe-hearts-plan_en [Accessed 5 Aug 2026]."},{"key":"2026092018554305631_j_cclm-2026-1439_ref_002","doi-asserted-by":"crossref","unstructured":"OECD. The State of Cardiovascular Health in the European Union. The State of Cardiovascular Health in the European Union 2025. https:\/\/doi.org\/10.1787\/EA7A15F4-EN.","DOI":"10.1787\/ea7a15f4-en"},{"key":"2026092018554305631_j_cclm-2026-1439_ref_003","unstructured":"A European Cardiovascular Health Plan: The Roadmap cardiovascular-alliance.eu n.d."},{"key":"2026092018554305631_j_cclm-2026-1439_ref_004","unstructured":"News Archives - EACH n.d. https:\/\/www.cardiovascular-alliance.eu\/category\/news\/ [Accessed 5 Aug 2026]."},{"key":"2026092018554305631_j_cclm-2026-1439_ref_005","doi-asserted-by":"crossref","unstructured":"Zubiran, R, Wolska, A, Amar, M, Sampson, M, Remaley, AT. Precision medicine for Lipids: the New US Guidelines for dyslipidemia. Clin Chem 2026;hvag083. https:\/\/doi.org\/10.1093\/CLINCHEM\/HVAG083.","DOI":"10.1093\/clinchem\/hvag083"},{"key":"2026092018554305631_j_cclm-2026-1439_ref_006","doi-asserted-by":"crossref","unstructured":"Langlois, MR. 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