{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T03:44:04Z","timestamp":1772941444128,"version":"3.50.1"},"reference-count":13,"publisher":"Walter de Gruyter GmbH","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2000,7,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>We evaluated the performance of the Emit<jats:sup>\u00ae<\/jats:sup> tox benzodiazepine and barbiturate assays (Dade Behring) and fluorescence polarisation immunoassay (FPIA) (Abbott) for use with serum determinations in preliminary therapeutic drug monitoring or acute drug intoxication detection.<\/jats:p>\n               <jats:p>Performance, as indicated by CVs, of the Emit<jats:sup>\u00ae<\/jats:sup> tox benzodiazepine and barbiturate assays and FPIA showed that both immunochemical techniques are precise and have good reproducibility.<\/jats:p>\n               <jats:p>For within-run studies, results from benzodiazepine determinations showed maximum CV values of 1.91% for the Emit<jats:sup>\u00ae<\/jats:sup> method and 2.65% for FPIA; results from barbiturate determinations showed maximum CV values of 2.01% for the Emit<jats:sup>\u00ae<\/jats:sup> method and 1.89% for FPIA.<\/jats:p>\n               <jats:p>For between-run studies, results from benzodiazepine determinations showed maximum CV values of 1.79% for the Emit<jats:sup>\u00ae<\/jats:sup> method and 1.12% for FPIA; results from barbiturate determinations showed maximum CV values of 2.09% for the Emit<jats:sup>\u00ae<\/jats:sup> method and 2.02% for FPIA.<\/jats:p>","DOI":"10.1515\/cclm.2000.089","type":"journal-article","created":{"date-parts":[[2004,10,21]],"date-time":"2004-10-21T08:30:46Z","timestamp":1098347446000},"page":"615-618","source":"Crossref","is-referenced-by-count":7,"title":["Evaluation of Emit\u00ae Tox Benzodiazepine and Barbiturate Assays on the Vitalab Viva Analyser and FPIA on the Abbott ADx Analyser"],"prefix":"10.1515","volume":"38","author":[{"given":"Corinne J.","family":"Charlier","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guy J.","family":"Plomteux","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","published-online":{"date-parts":[[2005,6,1]]},"reference":[{"key":"p_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/jat\/6.1.1","volume":"6","author":"Pegon Y","year":"1982","journal-title":"J Anal Toxicol"},{"key":"p_2","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1093\/jat\/15.2.63","volume":"15","author":"Fraser A","year":"1991","journal-title":"J Anal Toxicol"},{"key":"p_3","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1093\/jat\/6.1.22","volume":"6","author":"Slighton EL","year":"1982","journal-title":"J Anal Toxicol"},{"key":"p_4","first-page":"25","volume":"2","author":"Le TK","year":"1990","journal-title":"Toxicorama"},{"key":"p_5","first-page":"973","volume":"33","author":"Keegan C","year":"1987","journal-title":"Clin Chem"},{"key":"p_6","first-page":"151","volume":"44","author":"Wood JH","year":"1992","journal-title":"Pharmacol Rev"},{"key":"p_7","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1017\/S0767399X00003801","volume":"5","author":"Kovess V","year":"1990","journal-title":"Psychiatr Psychobiol"},{"key":"p_8","first-page":"281","author":"Nogue S","year":"1996","journal-title":"Amsterdam: Elsevier Science BV"},{"key":"p_9","doi-asserted-by":"publisher","DOI":"10.1177\/096032718400300203"},{"key":"p_10","first-page":"24","volume":"1","author":"Harvey JG","year":"1986","journal-title":"Br J Acc Emerg Med"},{"key":"p_11","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1093\/clinchem\/25.6.856","volume":"25","author":"McKichan J","year":"1979","journal-title":"Clin Chem"},{"key":"p_12","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1093\/clinchem\/37.6.804","volume":"37","author":"Moore CM","year":"1991","journal-title":"Clin Chem"},{"key":"p_13","first-page":"347","volume":"52","author":"Zorza G","year":"1994","journal-title":"Ann Biol Clin"}],"container-title":["cclm"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.degruyter.com\/document\/doi\/10.1515\/CCLM.2000.089\/xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.degruyter.com\/document\/doi\/10.1515\/CCLM.2000.089\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,14]],"date-time":"2022-03-14T14:43:32Z","timestamp":1647269012000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.degruyter.com\/document\/doi\/10.1515\/CCLM.2000.089\/html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,7,11]]},"references-count":13,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2005,6,1]]},"published-print":{"date-parts":[[2000,7,11]]}},"alternative-id":["10.1515\/CCLM.2000.089"],"URL":"https:\/\/doi.org\/10.1515\/cclm.2000.089","relation":{},"ISSN":["1434-6621"],"issn-type":[{"value":"1434-6621","type":"print"}],"subject":[],"published":{"date-parts":[[2000,7,11]]}}}