{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T13:50:21Z","timestamp":1761918621902},"reference-count":40,"publisher":"Walter de Gruyter GmbH","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2004,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Hyperhomocysteinemia is a risk factor in obstetrical complications such as pre-eclampsia, \u2018hemolysis, elevated liver enzymes, low platelet\u2019 (HELLP)-syndrome and placental insufficiency. The aim of our study was to investigate the alterations of homocysteine catabolism in these patients in relation to serum B-vitamins and renal function. Maternal fasting serum from preeclampsia (n = 24), HELLP (n = 20) and placental insufficiency (n = 25) patients at the time of diagnosis and pregnant controls (n = 34) was analyzed for homocysteine and its metabolites cystathionine and methylmalonic acid, the vitamins B<\/jats:p>","DOI":"10.1515\/cclm.2004.228","type":"journal-article","created":{"date-parts":[[2004,10,18]],"date-time":"2004-10-18T17:38:06Z","timestamp":1098121086000},"source":"Crossref","is-referenced-by-count":14,"title":["Alteration of homocysteine catabolism in pre-eclampsia, HELLP syndrome and placental insufficiency"],"prefix":"10.1515","volume":"42","author":[{"given":"Wolfgang","family":"Herrmann","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulrich","family":"H\u00fcbner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ines","family":"Koch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rima","family":"Obeid","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulrich","family":"Retzke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00fcrgen","family":"Geisel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","reference":[{"key":"ref341","first-page":"45","article-title":"Adequacy of maternal pyridoxine supplementation during pregnancy in relation to the vitamin status and growth of neonates at birth","volume":"6","author":"Chang","year":"1999","journal-title":"J Nutr Sci Vitaminol"},{"key":"ref01","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1046\/j.1525-1373.1999.d01-139.x","article-title":"Oxidative stress in the pathogenesis of pre - 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