{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T14:55:15Z","timestamp":1753887315818,"version":"3.41.2"},"reference-count":15,"publisher":"Walter de Gruyter GmbH","issue":"1","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,1,27]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec id=\"j_crpm-2023-0016_abs_001\">\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>This article outlines an unusual presentation of a premature infant born from a pre-eclamptic mother born with a presentation resembling a disseminated intravascular coagulation syndrome.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_crpm-2023-0016_abs_002\">\n                  <jats:title>Case presentation<\/jats:title>\n                  <jats:p>Pregnancy-induced hypertension, also known as pre-eclampsia, and premature birth pose significant risks to neonates, making the fetus more susceptible to immunodeficiencies and coagulopathies. This article highlights a premature infant born to a pre-eclamptic mother with multiple complications. Our case involved jaundice, neonatal meningitis, thrombocytopenia, leukopenia, neutropenia, hemorrhage, apnea, gastrointestinal defects, and periventricular leukomalacia. Often these complications are seen immediately after birth; these symptoms may present after a certain amount of time lapses if the neonates if afflicted with malignancy or a viral, fungal, or bacterial infection. Here we describe the case of a premature neonate born to a preeclamptic mother that experienced these complications one day after her birth.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_crpm-2023-0016_abs_003\">\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>This is the first known case of an infant experiencing a \u201cDIC-like\u201d syndrome without any diagnosis of a primary hematological malignancy or infection after a certain amount of time had lapsed since her birth. As complications in premature infants as well as those from pre-eclamptic mothers are common, this case report highlights a successful model of care. We also explore the effect of a peri-COVID setting on the presentation of this patient, as similar cases have occurred post-COVID-19.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1515\/crpm-2023-0016","type":"journal-article","created":{"date-parts":[[2023,10,25]],"date-time":"2023-10-25T07:41:02Z","timestamp":1698219662000},"source":"Crossref","is-referenced-by-count":0,"title":["DIC-like syndrome in a post-pre-eclampsia birth in a premature infant in a peri-COVID scenario"],"prefix":"10.1515","volume":"12","author":[{"given":"Taha F.","family":"Hassan","sequence":"first","affiliation":[{"name":"School of Medicine , Texas Tech Health Sciences Center , Lubbock , TX , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0220-2314","authenticated-orcid":false,"given":"Ryan D.","family":"Morgan","sequence":"additional","affiliation":[{"name":"School of Medicine , Texas Tech Health Sciences Center , Lubbock , TX , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akshay","family":"Raghuram","sequence":"additional","affiliation":[{"name":"School of Medicine , Texas Tech Health Sciences Center , Lubbock , TX , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benedicto C.","family":"Baronia","sequence":"additional","affiliation":[{"name":"Surgery , Texas Tech Health Sciences Center University Medical Hospital , Lubbock , TX , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","published-online":{"date-parts":[[2023,10,25]]},"reference":[{"key":"2023102507405800560_j_crpm-2023-0016_ref_001","doi-asserted-by":"crossref","unstructured":"Burton, GJ, Redman, CW, Roberts, JM, Moffett, A. Pre-eclampsia: pathophysiology and clinical implications. BMJ 2019;366:l2381. https:\/\/doi.org\/10.1136\/bmj.l2381.","DOI":"10.1136\/bmj.l2381"},{"key":"2023102507405800560_j_crpm-2023-0016_ref_002","doi-asserted-by":"crossref","unstructured":"Marins, LR, Anizelli, LB, Romanowski, MD, Sarquis, AL. How does preeclampsia affect neonates? Highlights in the disease\u2019s immunity. J\u00a0Matern Fetal Neonatal Med 2019;32:1205\u201312. https:\/\/doi.org\/10.1080\/14767058.2017.1401996.","DOI":"10.1080\/14767058.2017.1401996"},{"key":"2023102507405800560_j_crpm-2023-0016_ref_003","doi-asserted-by":"crossref","unstructured":"Davies, EL, Bell, JS, Bhattacharya, S. Preeclampsia and preterm delivery: a population-based case-control study. Hypertens Pregnancy 2016;35:510\u20139. https:\/\/doi.org\/10.1080\/10641955.2016.1190846.","DOI":"10.1080\/10641955.2016.1190846"},{"key":"2023102507405800560_j_crpm-2023-0016_ref_004","doi-asserted-by":"crossref","unstructured":"\u00d8deg\u00e5rd, RA, Vatten, LJ, Nilsen, ST, Salvesen, K\u00c5, Austgulen, R. Preeclampsia and fetal growth. Obstet Gynecol 2000;96:950\u20135. https:\/\/doi.org\/10.1097\/00006250-200012000-00016.","DOI":"10.1097\/00006250-200012000-00016"},{"key":"2023102507405800560_j_crpm-2023-0016_ref_005","doi-asserted-by":"crossref","unstructured":"Ward, RM, Beachy, JC. Neonatal complications following preterm birth. BJOG An Int J Obstet Gynaecol 2003;110:8\u201316. https:\/\/doi.org\/10.1046\/j.1471-0528.2003.00012.x.","DOI":"10.1016\/S1470-0328(03)00012-0"},{"key":"2023102507405800560_j_crpm-2023-0016_ref_006","doi-asserted-by":"crossref","unstructured":"Kalagiri, RR, Choudhury, S, Carder, T, Govande, V, Beeram, MR, Uddin, MN. Neonatal thrombocytopenia as a consequence of maternal preeclampsia. AJP Rep 2016;6:e42\u20137. https:\/\/doi.org\/10.1055\/s-0035-1565923.","DOI":"10.1055\/s-0035-1565923"},{"key":"2023102507405800560_j_crpm-2023-0016_ref_007","doi-asserted-by":"crossref","unstructured":"Venkatesh, KK, Strauss, RA, Westreich, DJ, Thorp, JM, Stamilio, DM, Grantz, KL. Adverse maternal and neonatal outcomes among women with preeclampsia with severe features <34\u00a0weeks gestation with versus without comorbidity. Pregnancy Hypertens 2020;20:75\u201382. https:\/\/doi.org\/10.1016\/j.preghy.2020.03.006.","DOI":"10.1016\/j.preghy.2020.03.006"},{"key":"2023102507405800560_j_crpm-2023-0016_ref_008","unstructured":"Institute of Medicine Committee on Understanding Premature B, Assuring Healthy O. The national academies collection: reports funded by national institutes of health. In: Behrman, RE, Butler, AS, editors. Preterm birth: causes, consequences, and prevention. Washington, DC: National Academies Press (US) Copyright \u00a9 2007, National Academy of Sciences; 2007."},{"key":"2023102507405800560_j_crpm-2023-0016_ref_009","doi-asserted-by":"crossref","unstructured":"VanVooren, DM, Bradshaw, WT, Blake, SM. Disseminated intravascular coagulation in the neonate. Neonatal Netw 2018;37:205\u201311. https:\/\/doi.org\/10.1891\/0730-0832.37.4.205.","DOI":"10.1891\/0730-0832.37.4.205"},{"key":"2023102507405800560_j_crpm-2023-0016_ref_010","unstructured":"Costello, RA, Nehring, SM. Disseminated intravascular coagulation. Treasure Island, FL: StatPearls Publishing Copyright \u00a9 2022, StatPearls Publishing LLC; 2022."},{"key":"2023102507405800560_j_crpm-2023-0016_ref_011","doi-asserted-by":"crossref","unstructured":"Arif, SH, Ahmad, I, Ali, SM, Khan, HM. Thrombocytopenia and bacterial sepsis in neonates. Indian J Hematol Blood Transfus 2012;28:147\u201351. https:\/\/doi.org\/10.1007\/s12288-011-0118-7.","DOI":"10.1007\/s12288-011-0118-7"},{"key":"2023102507405800560_j_crpm-2023-0016_ref_012","doi-asserted-by":"crossref","unstructured":"Fell, DB, Dimanlig-Cruz, S, Regan, AK, H\u00e5berg, SE, Gravel, CA, Oakley, L, et al.. Risk of preterm birth, small for gestational age at birth, and stillbirth after covid-19 vaccination during pregnancy: population based retrospective cohort study. BMJ 2022;378:e071416. https:\/\/doi.org\/10.1136\/bmj-2022-071416.","DOI":"10.1136\/bmj-2022-071416"},{"key":"2023102507405800560_j_crpm-2023-0016_ref_013","doi-asserted-by":"crossref","unstructured":"Karrow, NA, Shandilya, UK, Pelech, S, Wagter-Lesperance, L, McLeod, D, Bridle, B, et al.. Maternal COVID-19 vaccination and its potential impact on fetal and neonatal development. Vaccines 2021;9:1351. https:\/\/doi.org\/10.3390\/vaccines9111351.","DOI":"10.3390\/vaccines9111351"},{"key":"2023102507405800560_j_crpm-2023-0016_ref_014","doi-asserted-by":"crossref","unstructured":"Lee, PX, Ong, LC, Libau, EA, Alonso, S. Relative contribution of dengue IgG antibodies acquired during gestation or breastfeeding in mediating dengue disease enhancement and protection in type I interferon receptor-deficient mice. PLoS Neglected Trop Dis 2016;10:e0004805. https:\/\/doi.org\/10.1371\/journal.pntd.0004805.","DOI":"10.1371\/journal.pntd.0004805"},{"key":"2023102507405800560_j_crpm-2023-0016_ref_015","doi-asserted-by":"crossref","unstructured":"Mart\u00ednez G\u00f3mez, JM, Ong, LC, Lam, JH, Binte Aman, SA, Libau, EA, Lee, PX, et al.. Maternal antibody-mediated disease enhancement in type I interferon-deficient mice leads to lethal disease associated with liver damage. PLoS Neglected Trop Dis 2016;10:e0004536. https:\/\/doi.org\/10.1371\/journal.pntd.0004536.","DOI":"10.1371\/journal.pntd.0004536"}],"container-title":["Case Reports in Perinatal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.degruyter.com\/document\/doi\/10.1515\/crpm-2023-0016\/xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.degruyter.com\/document\/doi\/10.1515\/crpm-2023-0016\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,25]],"date-time":"2023-10-25T07:41:07Z","timestamp":1698219667000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.degruyter.com\/document\/doi\/10.1515\/crpm-2023-0016\/html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1,1]]},"references-count":15,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2023,10,25]]},"published-print":{"date-parts":[[2023,1,27]]}},"alternative-id":["10.1515\/crpm-2023-0016"],"URL":"https:\/\/doi.org\/10.1515\/crpm-2023-0016","relation":{},"ISSN":["2192-8959"],"issn-type":[{"type":"electronic","value":"2192-8959"}],"subject":[],"published":{"date-parts":[[2023,1,1]]},"article-number":"20230016"}}