{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T12:11:37Z","timestamp":1789560697467,"version":"build-2803163510"},"reference-count":21,"publisher":"Walter de Gruyter GmbH","issue":"1","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,23]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"j_crpm-2024-0014_abs_001\">\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Congenital glomuvenous malformations are uncommon vascular maformations caused by mutations in the glomulin gene that are either sporadic or dominantly inherited.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_crpm-2024-0014_abs_002\">\n                    <jats:title>Case presentation<\/jats:title>\n                    <jats:p>We describe the case of a fetal scalp mass\u00a0\u2013\u00a0a glomuvenous malformation\u00a0\u2013\u00a0detected prenatally in the third trimester of pregnancy. This defect was an isolated incidental finding without any other intra- or extracranial abnormalities. The pregnancy was managed in a tertiary fetal medicine unit, detailed investigations were performed and a plan for delivery was made following multidisciplinary input. The neonate was delivered following a planned caesarean section at 37\u201338\u00a0weeks. The mass was resected by the neurosurgical team on the first day of life and the baby was discharged in good health on day 7. The mass was sent for neuropathological examination, which confirmed a diagnosis of glomuvenous malformation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_crpm-2024-0014_abs_003\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Our case highlights the importance of third trimester assessment of fetal anatomy and the importance of prenatal diagnosis and multidisciplinary teamwork to improve perinatal outcomes in high-risk pregnancies. It also highlights that glomuvenous malformation should be considered in the differential diagnosis in pregnancies presenting with a subcutaneous scalp mass without an accompanying calvarial defect.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1515\/crpm-2024-0014","type":"journal-article","created":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T11:56:51Z","timestamp":1789559811000},"source":"Crossref","is-referenced-by-count":0,"title":["Prenatal diagnosis of a fetal scalp glomuvenous malformation\u2013\u00a0a case report"],"prefix":"10.1515","volume":"15","author":[{"given":"Tara","family":"Giacchino","sequence":"first","affiliation":[{"name":"Medway Fetal and Maternal Medicine Centre, Medway NHS Foundation Trust , Gillingham , UK"},{"name":"Institute of Medical Sciences, Canterbury Christ Church University, Rowan William\u2019s Court , Kent , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew","family":"Brown","sequence":"additional","affiliation":[{"name":"Medway Fetal and Maternal Medicine Centre, Medway NHS Foundation Trust , Gillingham , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bassel","family":"Zebian","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery , King\u2019s College Hospital NHS Foundation Trust , London , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Istvan","family":"Bodi","sequence":"additional","affiliation":[{"name":"Department of Clinical Neuropathology , King\u2019s College Hospital NHS Foundation Trust , London , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexia Egloff","family":"Collado","sequence":"additional","affiliation":[{"name":"Perinatal Imaging, Centre for Developing Brain, Guy\u2019s and St Thomas\u2019s Hospital , London , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7265-5442","authenticated-orcid":false,"given":"Ranjit","family":"Akolekar","sequence":"additional","affiliation":[{"name":"Medway Fetal and Maternal Medicine Centre, Medway NHS Foundation Trust , Gillingham , UK"},{"name":"Institute of Medical Sciences, Canterbury Christ Church University, Rowan William\u2019s Court , Kent , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2026,9,16]]},"reference":[{"key":"2026091611561734942_j_crpm-2024-0014_ref_001","doi-asserted-by":"crossref","unstructured":"Cho, JY, Lee, YH. Fetal tumors: prenatal ultrasonographic findings and clinical characteristics. Ultrasonography 2014;33:240\u201351. https:\/\/doi.org\/10.14366\/usg.14019.","DOI":"10.14366\/usg.14019"},{"key":"2026091611561734942_j_crpm-2024-0014_ref_002","doi-asserted-by":"crossref","unstructured":"Weissmann-Brenner, A, Kassif, E, Katorza, E, Achiron, R, Gilboa, Y. Soft-tissue mass of fetal scalp with abnormal course of dural sinuses. Ultrasound Obstet Gynecol 2018;52:126\u20137. https:\/\/doi.org\/10.1002\/uog.18817.","DOI":"10.1002\/uog.18817"},{"key":"2026091611561734942_j_crpm-2024-0014_ref_003","doi-asserted-by":"crossref","unstructured":"Sepulveda, A, Wong, AE, Sepulveda, S, Corral, E. Fetal scalp cyst or small meningocele: differential diagnosis with three-dimensional ultrasound. Fetal Diagn Ther 2011;30:77\u201380. https:\/\/doi.org\/10.1159\/000322918.","DOI":"10.1159\/000322918"},{"key":"2026091611561734942_j_crpm-2024-0014_ref_004","doi-asserted-by":"crossref","unstructured":"Okaro, E, Broussin, B, Ville, Y. Prenatal diagnosis of atypical cystic lesions of the fetal scalp. Ultrasound Obstet Gynecol 1998;12:442\u20134. https:\/\/doi.org\/10.1046\/j.1469-0705.1998.12060442.x.","DOI":"10.1046\/j.1469-0705.1998.12060442.x"},{"key":"2026091611561734942_j_crpm-2024-0014_ref_005","doi-asserted-by":"crossref","unstructured":"Carstensen, H, Juhler, M, B\u00f8geskov, L, Laursen, H. A report of nine newborns with congenital brain tumours. Childs Nerv Syst 2006;22:1427\u201331. https:\/\/doi.org\/10.1007\/s00381-006-0115-6.","DOI":"10.1007\/s00381-006-0115-6"},{"key":"2026091611561734942_j_crpm-2024-0014_ref_006","doi-asserted-by":"crossref","unstructured":"Tonni, G, Granese, R, Martins Santana, EF, Parise Filho, JP, Bottura, I, Borges Peixoto, A, et al.. Prenatally diagnosed fetal tumors of the head and neck: a systematic review with antenatal and postnatal outcomes over the past 20\u00a0years. J\u00a0Perinat Med 2017;45:149\u201365. https:\/\/doi.org\/10.1515\/jpm-2016-0074.","DOI":"10.1515\/jpm-2016-0074"},{"key":"2026091611561734942_j_crpm-2024-0014_ref_007","doi-asserted-by":"crossref","unstructured":"Tonni, G, Palmisano, M, Granese, R, Bonasoni, MP. Prenatal diagnosis of orofacial and neck tumors. In: Tonni, G, Sepulveda, W, Wong, AE, editors. Prenatal Diagnosis Of Orofacial Malformation. Springer International Publishing Switzerland; 2017, Chapter 6:81\u2013104 pp.","DOI":"10.1007\/978-3-319-32516-3_6"},{"key":"2026091611561734942_j_crpm-2024-0014_ref_008","doi-asserted-by":"crossref","unstructured":"Brouillard, P, Boon, LM, Mulliken, JB, Enjolras, O, Ghassib\u00e9, M, Warman, ML, et al.. Mutations in a novel factor, glomulin, are responsible for glomuvenous malformations (\u2018\u2018glomangiomas\u2019\u2019). Am J Hum Genet 2002;70:866\u201374. https:\/\/doi.org\/10.1086\/339492.","DOI":"10.1086\/339492"},{"key":"2026091611561734942_j_crpm-2024-0014_ref_009","doi-asserted-by":"crossref","unstructured":"Boon, LM, Mulliken, JB, Enjolras, O, Vikkula, M. Glomuvenous malformation (glomangioma) and venous malformation: distinct clinicopathologic and genetic entities. Arch Dermatol 2004;140:971\u20136. https:\/\/doi.org\/10.1001\/archderm.140.8.971.","DOI":"10.1001\/archderm.140.8.971"},{"key":"2026091611561734942_j_crpm-2024-0014_ref_010","doi-asserted-by":"crossref","unstructured":"Goujon, E, Cordoro, KM, Barat, M, Rousseau, T, Brouillard, P, Vikkula, M, et al.. Congenital plaque-type glomuvenous malformations associated with fetal pleural effusion and ascites. Pediatr Dermatol 2011;28:528\u201331. https:\/\/doi.org\/10.1111\/j.1525-1470.2010.01216.x.","DOI":"10.1111\/j.1525-1470.2010.01216.x"},{"key":"2026091611561734942_j_crpm-2024-0014_ref_011","doi-asserted-by":"crossref","unstructured":"Tejedor, M, Mart\u00edn-Santiago, A, G\u00f3mez, C, Fiol, M, Ben\u00edtez-Segura, I. Congenital plaque-type glomuvenous malformation associated with chylous ascites. Pediatr Dermatol 2010;27:673\u20135. https:\/\/doi.org\/10.1111\/j.1525-1470.2010.01337.x.","DOI":"10.1111\/j.1525-1470.2010.01337.x"},{"key":"2026091611561734942_j_crpm-2024-0014_ref_012","doi-asserted-by":"crossref","unstructured":"Mallory, SB, Enjolras, O, Boon, LM, Rogers, E, Berk, DR, Blei, F, et al.. Congenital plaque-type glomuvenous malformations presenting in childhood. Arch Dermatol 2006;142:892\u20136. https:\/\/doi.org\/10.1001\/archderm.142.7.892.","DOI":"10.1001\/archderm.142.7.892"},{"key":"2026091611561734942_j_crpm-2024-0014_ref_013","doi-asserted-by":"crossref","unstructured":"Chen, AY, Eide, M, Shwayder, T. Glomuvenous malformation in a boy with transposition of the great vessels: a case report and review of literature. Pediatr Dermatol 2009;26:70\u20134. https:\/\/doi.org\/10.1111\/j.1525-1470.2008.00826.x.","DOI":"10.1111\/j.1525-1470.2008.00826.x"},{"key":"2026091611561734942_j_crpm-2024-0014_ref_014","doi-asserted-by":"crossref","unstructured":"Taaffe, A, Barker, D, Wyatt, EH, Bury, HP. Glomus tumours: a clinico-pathological survey. Clin Exp Dermatol 1980;5:219\u201325. https:\/\/doi.org\/10.1111\/j.1365-2230.1980.tb01692.x.","DOI":"10.1111\/j.1365-2230.1980.tb01692.x"},{"key":"2026091611561734942_j_crpm-2024-0014_ref_015","doi-asserted-by":"crossref","unstructured":"Goodman, TF, Abele, DC. Multiple glomus tumors. A clinical and electron microscopic study. Arch Dermatol 1971;103:11\u201323. https:\/\/doi.org\/10.1001\/archderm.1971.04000130013002.","DOI":"10.1001\/archderm.1971.04000130013002"},{"key":"2026091611561734942_j_crpm-2024-0014_ref_016","doi-asserted-by":"crossref","unstructured":"Rudolph, R. Familial multiple glomangiomas. Ann Plast Surg 1993;30:183\u20135. https:\/\/doi.org\/10.1097\/00000637-199302000-00017.","DOI":"10.1097\/00000637-199302000-00017"},{"key":"2026091611561734942_j_crpm-2024-0014_ref_017","doi-asserted-by":"crossref","unstructured":"Iqbal, A, Cormack, GC, Scerri, G. Hereditary multiple glomangiomas. Br J Plast Surg 1998;51:32\u20137. https:\/\/doi.org\/10.1054\/bjps.1997.0116.","DOI":"10.1054\/bjps.1997.0116"},{"key":"2026091611561734942_j_crpm-2024-0014_ref_018","doi-asserted-by":"crossref","unstructured":"Parsons, ME, Russo, G, Fucich, L, Millikan, LE, Kim, R. Multiple glomus tumors. Int J Dermatol 1997;36:894\u2013900. https:\/\/doi.org\/10.1046\/j.1365-4362.1997.00368.x.","DOI":"10.1046\/j.1365-4362.1997.00368.x"},{"key":"2026091611561734942_j_crpm-2024-0014_ref_019","doi-asserted-by":"crossref","unstructured":"Ficara, A, Syngelaki, A, Hammami, A, Akolekar, R, Nicolaides, KH. Value of routine ultrasound examination at 35-37\u00a0weeks\u2019 gestation in diagnosis of fetal abnormalities. Ultrasound Obstet Gynecol 2020;55:75\u201380. https:\/\/doi.org\/10.1002\/uog.20857.","DOI":"10.1002\/uog.20857"},{"key":"2026091611561734942_j_crpm-2024-0014_ref_020","doi-asserted-by":"crossref","unstructured":"Drukker, L, Cavallaro, A, Salim, I, Ioannou, C, Impey, L, Papageorghiou, AT. How often do we incidentally find a fetal abnormality at the routine third-trimester growth scan? A population-based study. Am J Obstet Gynecol 2020;223:919.e1\u2013919.e13. https:\/\/doi.org\/10.1016\/j.ajog.2020.05.052.","DOI":"10.1016\/j.ajog.2020.05.052"},{"key":"2026091611561734942_j_crpm-2024-0014_ref_021","doi-asserted-by":"crossref","unstructured":"Syngelaki, A, Mitsigiorgi, R, Goadsby, J, Hamed, K, Akolekar, R, Nicolaides, KH. Routine 36-week scan: diagnosis of fetal abnormalities. Ultrasound Obstet Gynecol 2025;65:427\u201335.","DOI":"10.1002\/uog.29218"}],"container-title":["Case Reports in Perinatal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.degruyterbrill.com\/document\/doi\/10.1515\/crpm-2024-0014\/xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.degruyterbrill.com\/document\/doi\/10.1515\/crpm-2024-0014\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T11:57:02Z","timestamp":1789559822000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.degruyterbrill.com\/document\/doi\/10.1515\/crpm-2024-0014\/html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,1]]},"references-count":21,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,9,16]]},"published-print":{"date-parts":[[2026,1,23]]}},"alternative-id":["10.1515\/crpm-2024-0014"],"URL":"https:\/\/doi.org\/10.1515\/crpm-2024-0014","relation":{},"ISSN":["2192-8959"],"issn-type":[{"value":"2192-8959","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,1]]},"article-number":"20240014"}}