{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T04:14:32Z","timestamp":1778645672881,"version":"3.51.4"},"reference-count":17,"publisher":"Walter de Gruyter GmbH","issue":"1","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,23]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"j_crpm-2025-0028_abs_001\">\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Primary hyperaldosteronism can present during pregnancy. Due to its rarity and to the physiological changes occurring during pregnancy, diagnosis might be delayed with potential complications imposed on the mother and newborn.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_crpm-2025-0028_abs_002\">\n                    <jats:title>Case presentation<\/jats:title>\n                    <jats:p>We report a 46-years-old middle eastern patient with chronic hypertension, who conceived with assisted reproductive technologies and was diagnosed with PA. She was referred back to cardiology for re-evaluation of her resistant hypertension. Serum electrolytes showed low potassium, high aldosterone, and high renin to aldosterone ratio. Magnetic resonance imaging of the adrenal glands revealed a unilateral nodule in the left adrenal gland. The patient was maintained on three antihypertensives; unfortunately, her pregnancy was complicated by intrauterine growth restriction and preterm delivery for preeclampsia with severe features.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_crpm-2025-0028_abs_003\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Primary hyperaldosteronism is a rare complication of pregnancy that is challenging to diagnose. However, timely and accurate diagnosis are essential to initiate appropriate treatment to ensure optimal fetal and maternal outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1515\/crpm-2025-0028","type":"journal-article","created":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T03:57:16Z","timestamp":1778644636000},"source":"Crossref","is-referenced-by-count":0,"title":["Primary Hyper-aldosteronism in pregnancy: a case report with review of the literature"],"prefix":"10.1515","volume":"15","author":[{"given":"Elie","family":"Hobeika","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Faculty of Medicine , American University of Beirut , Beirut , Lebanon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dalia","family":"Malaeb","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology , Kanad Hospital , Al Ain , Abu Dhabi , United Arab Emirates"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dina","family":"Chamsy","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Faculty of Medicine , American University of Beirut , Beirut , Lebanon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdallah","family":"Adra","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Faculty of Medicine , American University of Beirut , Beirut , Lebanon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nabil","family":"El Khoury","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Faculty of Medicine , American University of Beirut , Beirut , Lebanon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9200-1865","authenticated-orcid":false,"given":"Anwar H.","family":"Nassar","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Faculty of Medicine , American University of Beirut , Beirut , Lebanon"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","published-online":{"date-parts":[[2026,5,13]]},"reference":[{"key":"2026051303570946861_j_crpm-2025-0028_ref_001","doi-asserted-by":"crossref","unstructured":"Kersten, M, Hancke, K, Janni, W, Kraft, K. Pregnancy induced Cushing\u2019s syndrome and primary aldosteronism: a case report. BMC Preg Childbir 2020;20:421. https:\/\/doi.org\/10.1186\/s12884-020-03117-1.","DOI":"10.1186\/s12884-020-03117-1"},{"key":"2026051303570946861_j_crpm-2025-0028_ref_002","doi-asserted-by":"crossref","unstructured":"Forestiero, V, Sconfienza, E, Mulatero, P, Monticone, S. Primary aldosteronism in pregnancy. Rev Endo Meta Dis 2023;24:39\u201348. https:\/\/doi.org\/10.1007\/s11154-022-09729-6.","DOI":"10.1007\/s11154-022-09729-6"},{"key":"2026051303570946861_j_crpm-2025-0028_ref_003","doi-asserted-by":"crossref","unstructured":"August, P. Hypertension in a pregnant patient: how I treat. Clin J Am Soc Nephrol 2019;14:1655\u20137. https:\/\/doi.org\/10.2215\/cjn.01030119.","DOI":"10.2215\/CJN.01030119"},{"key":"2026051303570946861_j_crpm-2025-0028_ref_004","doi-asserted-by":"crossref","unstructured":"Riester, A, Reincke, M. Progress in primary aldosteronism: mineralocorticoid receptor antagonists and management of primary aldosteronism in pregnancy. Euro J Endo 2015;172:R23\u201330. https:\/\/doi.org\/10.1530\/eje-14-0444.","DOI":"10.1530\/EJE-14-0444"},{"key":"2026051303570946861_j_crpm-2025-0028_ref_005","unstructured":"Shiraishi, K, Kikuta, K, Nitta, Y, Matsuyama, H. Laparoscopic adrenalectomy due to primary aldosteronism during pregnancy. Hinyokika kiyo. Acta Uro Japon 2014;60:381\u20135."},{"key":"2026051303570946861_j_crpm-2025-0028_ref_006","doi-asserted-by":"crossref","unstructured":"Eguchi, K, Hoshide, S, Nagashima, S, Maekawa, T, Sasano, H, Kario, K. An adverse pregnancy-associated outcome due to overlooked primary aldosteronism. 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