{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T21:02:41Z","timestamp":1784322161920,"version":"3.55.0"},"reference-count":37,"publisher":"Walter de Gruyter GmbH","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,7,29]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"j_dmpt-2024-0029_abs_001\">\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>\n                      The research aims to investigate the effect of vitamin D supplementation on the efficacy of\n                      <jats:italic>Helicobacter pylori<\/jats:italic>\n                      eradication therapy and to find new drug combinations for the eradication of the bacterium.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_dmpt-2024-0029_abs_002\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A total of 128 children participated in the research. They were distributed under the following criteria: group A were children who tested positive for\n                      <jats:italic>H.\u00a0pylori<\/jats:italic>\n                      and were treated with the standard so-called triple therapy including vitamin D; group B were children who tested positive for\n                      <jats:italic>H.\u00a0pylori<\/jats:italic>\n                      and received the standard triple therapy without including vitamin D in the treatment; and group C were children who tested negative for\n                      <jats:italic>H.\u00a0pylori<\/jats:italic>\n                      . After endoscopic examination, additional venous blood samples were taken from the children to determine vitamin D levels. A controlled study was carried out 45\u00a0days after the initial treatment.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_dmpt-2024-0029_abs_003\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The overall success rate of eradication therapy was 84.1\u202f%. In group A, the success rate of treatment was 93.5\u202f%, contrary to group B, where the success rate was 75\u202f%. Although there was a difference in the percentage of\n                      <jats:italic>H.\u00a0pylori<\/jats:italic>\n                      eradication therapy in the main group compared to the control group, there was no significant difference in group B. The success rate of eradication is p=0.082.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_dmpt-2024-0029_abs_004\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      Following the research results, the addition of vitamin D to the standard triple therapy regimen for\n                      <jats:italic>H.\u00a0pylori<\/jats:italic>\n                      had no effect. It can therefore be concluded that vitamin D does not significantly increase the efficacy of eradication therapy.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1515\/dmpt-2024-0029","type":"journal-article","created":{"date-parts":[[2024,7,12]],"date-time":"2024-07-12T00:05:33Z","timestamp":1720742733000},"page":"59-67","source":"Crossref","is-referenced-by-count":1,"title":["<i>Helicobacter pylori<\/i>\n                    eradication therapy for children"],"prefix":"10.1515","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-0108-8940","authenticated-orcid":false,"given":"Kairat","family":"Rysbekov","sequence":"first","affiliation":[{"name":"Department of Pediatric Diseases with Courses Cardio-Rheumatology and Gastroenterology , 217968 Astana Medical University , Astana , Kazakhstan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sagira","family":"Abrakhmanova","sequence":"additional","affiliation":[{"name":"Department of Pediatric Diseases with Courses Cardio-Rheumatology and Gastroenterology , 217968 Astana Medical University , Astana , Kazakhstan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rashida","family":"Satybaeva","sequence":"additional","affiliation":[{"name":"Department of Pediatric Diseases with Courses Cardio-Rheumatology and Gastroenterology , 217968 Astana Medical University , Astana , Kazakhstan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yekaterina","family":"Starosvetova","sequence":"additional","affiliation":[{"name":"Department of Pediatric Diseases with Courses Cardio-Rheumatology and Gastroenterology , 217968 Astana Medical University , Astana , Kazakhstan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Almagul","family":"Kushugulova","sequence":"additional","affiliation":[{"name":"Laboratory of Human Microbiome and Longevity , National Laboratory Astana , Astana , Kazakhstan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2024,7,15]]},"reference":[{"key":"2026071720035366132_j_dmpt-2024-0029_ref_001","doi-asserted-by":"crossref","unstructured":"Katelaris, P, Hunt, R, Bazzoli, F, Cohen, H, Fock, KM, Gemilyan, M, et al.. 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