{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T07:46:06Z","timestamp":1765525566546,"version":"3.48.0"},"reference-count":32,"publisher":"Walter de Gruyter GmbH","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,11,26]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"j_dx-2019-0003_s_999_w2aab3b7c16b1b6b1aab1c16b1Aa\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Diagnostic error in cerebral venous thrombosis (CVT) has been understudied despite the harm associated with misdiagnosis of other cerebrovascular diseases as well as the known challenges of evaluating non-specific neurological symptoms in clinical practice.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_dx-2019-0003_s_998_w2aab3b7c16b1b6b1aab1c16b2Aa\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      We conducted a retrospective cohort study of CVT patients hospitalized at a single center. Two independent reviewers used a medical record review tool, the Safer Dx Instrument, to identify diagnostic errors. Demographic and clinical factors were abstracted. We compared subjects with and without a diagnostic error using the t-test for continuous variables and the chi-square (\u03c7\n                      <jats:sup>2<\/jats:sup>\n                      ) test or Fisher\u2019s exact test for categorical variables; an alpha of 0.05 was the cutoff for significance.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_dx-2019-0003_s_997_w2aab3b7c16b1b6b1aab1c16b3Aa\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 72 CVT patients initially met study inclusion criteria; 19 were excluded due to incomplete medical records. Of the 53 patients included in the final analysis, the mean age was 48 years and 32 (60.4%) were women. Diagnostic error occurred in 11 cases [20.8%; 95% confidence interval (CI) 11.8\u201333.6%]. Subjects with diagnostic errors were younger (42 vs. 49 years, p\u2009=\u20090.13), more often women (81.8% vs. 54.8%, p\u2009=\u20090.17), and were significantly more likely to have a past medical history of a headache disorder prior to the index CVT visit (7.1% vs. 36.4%, p\u2009=\u20090.03).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_dx-2019-0003_s_996_w2aab3b7c16b1b6b1aab1c16b4Aa\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Nearly one in five patients with complete medical records experienced a diagnostic error. Prior history of headache was the only evaluated clinical factor that was more common among those with an error in diagnosis. Future work on distinguishing primary from secondary headaches to improve diagnostic accuracy in acute neurological disease is warranted.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1515\/dx-2019-0003","type":"journal-article","created":{"date-parts":[[2019,7,4]],"date-time":"2019-07-04T12:20:07Z","timestamp":1562242807000},"page":"361-367","source":"Crossref","is-referenced-by-count":8,"title":["Assessing diagnostic error in cerebral venous thrombosis via detailed chart review"],"prefix":"10.1515","volume":"6","author":[{"given":"Ava L.","family":"Liberman","sequence":"first","affiliation":[{"name":"Department of Neurology , Montefiore Medical Center, Albert Einstein College of Medicine , Bronx , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ekaterina","family":"Bakradze","sequence":"additional","affiliation":[{"name":"Department of Neurology , University of Alabama at Birmingham , Birmingham , AL , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daryl C.","family":"Mchugh","sequence":"additional","affiliation":[{"name":"Department of Neurology , Montefiore Medical Center, Albert Einstein College of Medicine , Bronx , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles C.","family":"Esenwa","sequence":"additional","affiliation":[{"name":"Department of Neurology , Montefiore Medical Center, Albert Einstein College of Medicine , Bronx , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard B.","family":"Lipton","sequence":"additional","affiliation":[{"name":"Department of Neurology , Montefiore Medical Center, Albert Einstein College of Medicine , Bronx , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","published-online":{"date-parts":[[2019,7,4]]},"reference":[{"key":"2025121207042810974_j_dx-2019-0003_ref_001_w2aab3b7c16b1b6b1ab2b1b1Aa","unstructured":"Troxel, the Doctor\u2019s company [online]. thedoctors.com\/ KnowledgeCenter\/Publications\/TheDoctorsAdvocate\/Diagnostic- Error-in-Medical-Practice-by-Specialty. 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