{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T06:11:54Z","timestamp":1772863914100,"version":"3.50.1"},"reference-count":10,"publisher":"Walter de Gruyter GmbH","issue":"1","license":[{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,2,27]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"j_dx-2023-0142_abs_001\">\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>The misdiagnosis of appendicitis remains frequent. Better understanding of its clinical evolution over time would decrease the incidence of misdiagnosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_dx-2023-0142_abs_002\">\n                    <jats:title>Case presentation<\/jats:title>\n                    <jats:p>At the Society to Improve Diagnosis in medicine conference in Cleveland Ohio in October 2023, Alice Tapper and her father, CNN journalist Jake Tapper, presented her case of misdiagnosed appendicitis. Thanks to meticulous notes and a detailed timeline, the case vividly demonstrates the protean nature of appendicitis as well as the cognitive pitfalls of clinicians who treat\u00a0it.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_dx-2023-0142_abs_003\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>McBurney's point tenderness is over-emphasized as the key to the diagnosis of appendicitis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1515\/dx-2023-0142","type":"journal-article","created":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T10:57:21Z","timestamp":1754045841000},"page":"125-129","source":"Crossref","is-referenced-by-count":0,"title":["Appendicitis: common and commonly missed\u00a0\u2013\u00a0the story of Alice Tapper"],"prefix":"10.1515","volume":"13","author":[{"given":"Antonio J.","family":"Dajer","sequence":"first","affiliation":[{"name":"Weill Cornell Department of Emergency Medicine , New York , NY , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew P.J.","family":"Olson","sequence":"additional","affiliation":[{"name":"Division of Hospital Medicine, Department of Medicine, Division of Pediatric Hospital Medicine, Department of Pediatrics , University of Minnesota Medical School , Minneapolis , MN , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","published-online":{"date-parts":[[2025,8,1]]},"reference":[{"key":"2026030615414908008_j_dx-2023-0142_ref_001","unstructured":"Jacob, D, Silverstone, L, Knipe, H, Le, L, Bell, D. Acute appendicitis. Radiopaedia.org\/10.53347\/rlD-922 2025 (Last revised 4 July 2025)."},{"key":"2026030615414908008_j_dx-2023-0142_ref_002","doi-asserted-by":"crossref","unstructured":"Chartier, LB, Ovens, M, Hayes, M, Davis, B, Calder, L, Schull, M, et al.. Improving quality of care through a mandatory provincial audit program. Ann Emerg Med 2021;77:193\u2013202. https:\/\/doi.org\/10.1016\/j.annemergmed.2020.09.449.","DOI":"10.1016\/j.annemergmed.2020.09.449"},{"key":"2026030615414908008_j_dx-2023-0142_ref_003","doi-asserted-by":"crossref","unstructured":"Mahajan, P, Basu, T, Pai, C, Singh, H, Petersen, N, Bellolio, F, et al.. Factors associated with potentially missed diagnosis of appendicitis in the emergency department. JAMA Netw Open 2020;3:e200612. https:\/\/doi.org\/10.1001\/jamanetworkopen.2020.0612.","DOI":"10.1001\/jamanetworkopen.2020.0612"},{"key":"2026030615414908008_j_dx-2023-0142_ref_004","doi-asserted-by":"crossref","unstructured":"Vissers, R, Lennarz, W. Pitfalls in appendicitis. Emerg Med Clin 2010;28:103\u201318. https:\/\/doi.org\/10.1016\/j.emc.2009.09.003.","DOI":"10.1016\/j.emc.2009.09.003"},{"key":"2026030615414908008_j_dx-2023-0142_ref_005","doi-asserted-by":"crossref","unstructured":"D\u2019Souza, N. Appendicitis. BMJ Clin Evid 2011;2011:0408.","DOI":"10.1055\/s-0030-1259662"},{"key":"2026030615414908008_j_dx-2023-0142_ref_006","unstructured":"Cope, Z, Silen, W. Cope\u2019s early diagnosis of the acute abdomen, 22nd ed. New York, NY: Oxford University Press; 2010:81\u201383, 87, 88 pp."},{"key":"2026030615414908008_j_dx-2023-0142_ref_007","unstructured":"McBurney, C. Experience with early operative interference in cases of disease of the vermiform appendix. N\u00a0Y Med J 1889;50:676\u201384."},{"key":"2026030615414908008_j_dx-2023-0142_ref_008","doi-asserted-by":"crossref","unstructured":"Becker, T, Kharbanda, A, Bachur, R. Atypical clinical features of pediatric appendicitis. Acad EM 2007;14:124\u20139. https:\/\/doi.org\/10.1197\/j.aem.2006.08.009.","DOI":"10.1197\/j.aem.2006.08.009"},{"key":"2026030615414908008_j_dx-2023-0142_ref_009","doi-asserted-by":"crossref","unstructured":"Iftikar, M, Dar, SH, Rahman, UA, Butt, MJ, Sajjad, M, Hayat, U, et al.. Comparison of Alvarado score and pediatric appendicitis score for clinical diagnosis of acute appendicitis in children\u00a0\u2013\u00a0a prospective study. Ann Pediatr Surg 2021;17. https:\/\/doi.org\/10.1186\/s43159-021-00079-7. article 10.","DOI":"10.1186\/s43159-021-00079-7"},{"key":"2026030615414908008_j_dx-2023-0142_ref_010","doi-asserted-by":"crossref","unstructured":"Binkovitz, L, Unsdorfer, KML, Thapa, P, Kolbe, AB, Hull, NC, Zingula, SN, et al.. Pediatric appendiceal ultrasound\u00a0\u2013\u00a0accuracy, determinacy and clinical outcome. Pediatr Radiol 2015;45:1934\u201344. https:\/\/doi.org\/10.1007\/s00247-015-3432-7.","DOI":"10.1007\/s00247-015-3432-7"}],"container-title":["Diagnosis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.degruyterbrill.com\/document\/doi\/10.1515\/dx-2023-0142\/xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.degruyterbrill.com\/document\/doi\/10.1515\/dx-2023-0142\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T15:42:11Z","timestamp":1772811731000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.degruyterbrill.com\/document\/doi\/10.1515\/dx-2023-0142\/html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,1]]},"references-count":10,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,2,25]]},"published-print":{"date-parts":[[2026,2,27]]}},"alternative-id":["10.1515\/dx-2023-0142"],"URL":"https:\/\/doi.org\/10.1515\/dx-2023-0142","relation":{},"ISSN":["2194-802X"],"issn-type":[{"value":"2194-802X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,1]]}}}