{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T15:34:24Z","timestamp":1758814464428},"reference-count":6,"publisher":"Walter de Gruyter GmbH","issue":"1","license":[{"start":{"date-parts":[[2015,3,1]],"date-time":"2015-03-01T00:00:00Z","timestamp":1425168000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,3,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We present a 60-year-old male patient who, three months after a holiday in Southern Greece, found a small \u2018pimple\u2019 on his back, which gradually got as big as a small walnut, the central part becoming ulcerated and scabby. Dermatological examination found an erythematous-to-livid nodular lesion on the right shoulder; it was 16 mm in diameter with central ulceration, covered with brownish crust which discharged pus-like secretion upon pressure. Microscope examination of Romanowsky-Giemsa stained lesion material detected amastigote forms of<jats:italic>Leishmania tropica<\/jats:italic>. The culture investigation and serological tests for leishmaniasis were negative. Dermoscopy of the lesion found the following features: erythema, hyperkeratosis, central ulceration covered with brownish crust, \u201cyellow tears-like\u201d structures and \u201cwhite starburst-like\u201d patterns, and various vascular structures (including dotted vessels, comma-shaped vessels, hairpin- and glomerular-like vessels). The patient was diagnosed with cutaneous leishmaniasis and underwent four cryotherapy sessions every other week with excellent therapeutic results - complete resolution of infiltrate with subsequent gentle hypopigmented scarring. In conclusion, dermoscopy is an easily accessible non-invasive method which can be useful for the diagnosis of cutaneous leishmaniasis. Cryotherapy is the treatment of choice for single skin lesions.<\/jats:p>","DOI":"10.1515\/folmed-2015-0021","type":"journal-article","created":{"date-parts":[[2015,10,2]],"date-time":"2015-10-02T13:53:01Z","timestamp":1443793981000},"page":"65-68","source":"Crossref","is-referenced-by-count":6,"title":["Cutaneous Leishmaniasis \u2013 Dermoscopic Findings And Cryotherapy"],"prefix":"10.1515","volume":"57","author":[{"given":"Hristo P.","family":"Dobrev","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Desislava G.","family":"Nocheva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dimitar Iv.","family":"Vuchev","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rumyana D.","family":"Grancharova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","reference":[{"key":"ref31","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1111\/j.1365-4632.2012.05815.x","article-title":"Cutaneous leishmaniasis : new dermoscopic findings","volume":"52","author":"Y\u00fccel","year":"2013","journal-title":"Int J Dermatol"},{"key":"ref81","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1111\/j.1365-4632.2005.02628.x","article-title":"Treatment of cutaneous leishmaniasis with cryosurgery","volume":"44","author":"Panagiotopoulos","year":"2005","journal-title":"Int J Dermatol"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1111\/j.1365-2133.2008.08986.x","article-title":"Dermoscopy of Cutaneous Leishmaniasis","volume":"160","author":"Llambrich","year":"2009","journal-title":"Br J Dermatol"},{"key":"ref101","doi-asserted-by":"crossref","first-page":"172","DOI":"10.4269\/ajtmh.2009.80.172","article-title":"Efficacy of Cryotherapy versus Intralesional Meglumine Antimoniate for Treatment of Cutaneous Leishmaniasis in Children","volume":"80","author":"Layegh","year":"2009","journal-title":"Am J Trop Med Hyg"},{"key":"ref91","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1016\/j.jaad.2007.12.032","article-title":"Efficacy of a weekly cryotherapy regimen to treat Leishmania major cutaneous leishmaniasis","volume":"58","author":"Mosleh","year":"2008","journal-title":"J Am Acad Dermatol"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"1361","DOI":"10.1111\/ijd.12114","article-title":"Dermoscopic features of cutaneous leishmaniasis","volume":"52","author":"Taheri","year":"2013","journal-title":"Int J Dermatol"}],"container-title":["Folia Medica"],"original-title":[],"link":[{"URL":"http:\/\/content.sciendo.com\/view\/journals\/folmed\/57\/1\/article-p65.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.degruyter.com\/view\/j\/folmed.2015.57.issue-1\/folmed-2015-0021\/folmed-2015-0021.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,21]],"date-time":"2020-10-21T09:05:52Z","timestamp":1603271152000},"score":1,"resource":{"primary":{"URL":"http:\/\/archive.sciendo.com\/FOLMED\/folmed.2015.57.issue-1\/folmed-2015-0021\/folmed-2015-0021.pdf"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,3,1]]},"references-count":6,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.1515\/folmed-2015-0021","relation":{},"ISSN":["1314-2143"],"issn-type":[{"value":"1314-2143","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,3,1]]}}}