{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,19]],"date-time":"2026-07-19T02:45:53Z","timestamp":1784429153572,"version":"3.55.0"},"reference-count":23,"publisher":"Walter de Gruyter GmbH","issue":"1","license":[{"start":{"date-parts":[[2017,3,1]],"date-time":"2017-03-01T00:00:00Z","timestamp":1488326400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,3,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n\t\t\t\t<jats:p> Aim: The present study aimed at identifying the pattern of patients with critical limb ischemia (CLI) compared with those with peripheral arterial occlusive disease (PAOD).<\/jats:p>\n\t\t\t\t<jats:p>Materials and methods: A four-year retrospective study was conducted with patients hospitalized in the Second Surgical Clinic at the Emergency County Hospital Cluj-Napoca. The medical charts of patients with PAOD (n=466) and CLI (n=223) were reviewed and data were collected.<\/jats:p>\n\t\t\t\t<jats:p>Results: The study included 689 patients; mean age 67 years for PAOD patients and 65 years for CLI patients. A significantly higher percentage of patients were male in both groups (79.25%, P &lt; 0.0001). Most of the patients in both groups had received at least a secondary education (P &lt; 0.0001). Most of the subjects in both groups were smokers (&gt;71.30%) with no difference between groups (P = 0.566). No significant differences were found between the groups in comorbidities (diabetes, arterial blood hypertension, cardiac ischemia, rhythm disorders, P &gt; 0.05). There were more CLI patients that were overweight than overweight patients with PAOD (P = 0.0004). High serum cholesterol (&gt;200 mg\/dL) and triglycerides (&gt;150 mg\/dL) levels were found in the CLI group (P &lt; 0.05). Age was identified as a risk factors for amputation (OR = 1.03, 95%Cl [1.01\u22121.05], P = 0.0012).<\/jats:p>\n\t\t\t\t<jats:p>Conclusions: The profile of a patient with critical limb ischemia and peripheral arterial occlusive disease is a 65-67-year-old male smoker with at least a secondary education. The CLI patient is overweight with pathological serum levels of cholesterol and triglycerides.<\/jats:p>","DOI":"10.1515\/folmed-2017-0014","type":"journal-article","created":{"date-parts":[[2017,4,6]],"date-time":"2017-04-06T10:03:35Z","timestamp":1491473015000},"page":"14-22","source":"Crossref","is-referenced-by-count":10,"title":["Demographic and Comorbidity Pattern of Patients with Critical Limb Ischemia"],"prefix":"10.1515","volume":"59","author":[{"given":"R\u0103zvan A.","family":"Ciocan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sorana D.","family":"Bolboac\u0103","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u015eerban","family":"R\u0103dulescu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bogdan","family":"Stancu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andra","family":"Ciocan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia D.","family":"Gherman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","reference":[{"key":"ref211","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1093\/oxfordjournals.aje.a116294","article-title":"Smoking lipids glucose intolerance , and blood pressure as risk factors for peripheral atherosclerosis compared with ischemic heart disease in the Edinburgh Arterial Study","volume":"135","author":"Fowkes","year":"1992","journal-title":"Am J Epidemiol"},{"key":"ref261","first-page":"231","article-title":"Aortoiliac insuffi ciency : long - term experience with stent placement for treatment","author":"Murphy","year":"2004","journal-title":"Radiology"},{"key":"ref11","first-page":"1996","article-title":"Patterns of treatment for peripheral arterial disease in the United States","volume":"49","author":"Rowe","year":"2005","journal-title":"J Vasc Surg"},{"key":"ref271","doi-asserted-by":"crossref","first-page":"32","DOI":"10.4103\/0973-3930.43096","article-title":"Independent risk factors for amputation in diabetic foot","volume":"28","author":"Shojaiefard","year":"2008","journal-title":"Int J Diabetes Dev Ctries"},{"key":"ref21","first-page":"333","article-title":"Risk factors for atherosclerotic cardiovascular outcomes in different arterial territories","volume":"1","author":"Kanne","year":"1994","journal-title":"J Cardiovasc Risk"},{"key":"ref91","first-page":"57","article-title":"Infl uence of risk factors and comorbidities on the successful therapy and survival of patients with critical limb ischemia","volume":"86","author":"Constantinescu","year":"2013","journal-title":"Clujul Med"},{"key":"ref241","first-page":"1477","article-title":"[ Iloprost in the treatment of ischemic tissue lesions in diabetics Results of a placebo - controlled multicenter study with a stable prostacyclin derivative","volume":"120","author":"Brock","year":"1990","journal-title":"Schweiz Med Wochenschr"},{"key":"ref31","first-page":"282","article-title":"Does endovascular treatment of infra - inguinal arterial disease with drug - eluting stents offer better results than angioplasty with or without bare metal stents ? 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