{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,11,4]],"date-time":"2022-11-04T00:29:30Z","timestamp":1667521770175},"reference-count":0,"publisher":"Walter de Gruyter GmbH","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biological Chemistry"],"published-print":{"date-parts":[[2012,3,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Cancer procoagulant is present only in malignant tumours and the undifferentiated tissues of human placenta. Its possible role in angiogenesis and metastasis was investigated. Cancer procoagulant increased the steady-state mRNA level of <jats:italic>L1 cell adhesion molecule<\/jats:italic> (<jats:italic>L1CAM<\/jats:italic>) in MCF-7 breast cancer cells and E14 mouse embryonic stem cells (MESCs), while an increase in <jats:italic>angiogenin<\/jats:italic> mRNA was observed in MDA-MB-231 breast cancer cells. Furthermore, production of vascular endothelial growth factor (VEGF) protein in MCF-7 breast cancer cells and E14 MESCs, but decreased in MDA-MB-231 breast cancer cells. We conclude that cancer procoagulant could potentially play a part in angiogenesis in cancer and vascular development during embryonic development.<\/jats:p>","DOI":"10.1515\/hsz-2011-0177","type":"journal-article","created":{"date-parts":[[2012,3,20]],"date-time":"2012-03-20T20:25:27Z","timestamp":1332275127000},"page":"113-121","source":"Crossref","is-referenced-by-count":4,"title":["The effect of cancer procoagulant on expression of metastatic and angiogenic markers in breast cancer and embryonic stem cell lines"],"prefix":"10.1515","volume":"393","author":[{"given":"Nalise Low Ah","family":"Kee","sequence":"first","affiliation":[{"name":"Department of Biochemistry and Microbiology, Nelson Mandela Metropolitan University, P.O. Box 77000, Port Elizabeth 6031, South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryno J.","family":"Naud\u00e9","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Microbiology, Nelson Mandela Metropolitan University, P.O. Box 77000, Port Elizabeth 6031, South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gregory L.","family":"Blatch","sequence":"additional","affiliation":[{"name":"Biomedical Biotechnology Research Unit, Department of Biochemistry, Microbiology and Biotechnology, Rhodes University, P.O. Box 94, Grahamstown 6140, South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carminita L.","family":"Frost","sequence":"additional","affiliation":[{"name":"Biomedical Biotechnology Research Unit, Department of Biochemistry, Microbiology and Biotechnology, Rhodes University, P.O. Box 94, Grahamstown 6140, South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","published-online":{"date-parts":[[2012,3,1]]},"container-title":["bchm"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.degruyter.com\/view\/j\/bchm.2012.393.issue-3\/hsz-2011-0177\/hsz-2011-0177.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.degruyter.com\/document\/doi\/10.1515\/hsz-2011-0177\/xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.degruyter.com\/document\/doi\/10.1515\/hsz-2011-0177\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,14]],"date-time":"2022-03-14T15:22:35Z","timestamp":1647271355000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.degruyter.com\/document\/doi\/10.1515\/hsz-2011-0177\/html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,3,1]]},"references-count":0,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2012,3,1]]},"published-print":{"date-parts":[[2012,3,1]]}},"alternative-id":["10.1515\/hsz-2011-0177"],"URL":"https:\/\/doi.org\/10.1515\/hsz-2011-0177","relation":{},"ISSN":["1437-4315","1431-6730"],"issn-type":[{"value":"1437-4315","type":"electronic"},{"value":"1431-6730","type":"print"}],"subject":[],"published":{"date-parts":[[2012,3,1]]}}}