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In particular, we focus on morphological changes, membrane oxidative damage, altered membrane fatty acid profile, and aberrant skeletal organization in erythrocytes from patients with typical Rett syndrome and<jats:italic>MeCP2<\/jats:italic>gene mutations. The beneficial effects of \u03c9-3 polyunsaturated fatty acids (PUFAs) are also summarized for this condition to be considered as a \u2018model\u2019 condition for autism spectrum disorders.<\/jats:p>","DOI":"10.1515\/hsz-2015-0117","type":"journal-article","created":{"date-parts":[[2015,5,12]],"date-time":"2015-05-12T17:01:06Z","timestamp":1431450066000},"page":"1233-1240","source":"Crossref","is-referenced-by-count":11,"title":["Red blood cells in Rett syndrome: oxidative stress, morphological changes and altered membrane organization"],"prefix":"10.1515","volume":"396","author":[{"given":"Lucia","family":"Ciccoli","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudio","family":"De Felice","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvia","family":"Leoncini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cinzia","family":"Signorini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessio","family":"Cortelazzo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gloria","family":"Zollo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandra","family":"Pecorelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcello","family":"Rossi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joussef","family":"Hayek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","reference":[{"key":"ref411","first-page":"140","article-title":"deficiency neuropathology in recurrent affective disorders","author":"McNamara","year":"2010","journal-title":"prefrontal cortex Nutr"},{"key":"ref551","first-page":"13","article-title":"Exposure of human erythrocytes to oxygen radicals causes loss of deformability increased osmotic fragility lipid peroxidation and protein degradation","volume":"23","author":"Srour","year":"2000","journal-title":"Clin Hemorheol"},{"key":"ref1151","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1212\/WNL.0b013e318249f6a9","article-title":"Red blood cell \u03c9 fatty acid levels and markers of accelerated brain","author":"Tan","year":"2012","journal-title":"aging Neurology"},{"key":"ref291","article-title":"in autism Front","author":"Goldani","year":"2014","journal-title":"Biomarkers Psychiatry"},{"key":"ref431","first-page":"101","article-title":"Nans Native ultrastructure of the red cell cytoskeleton by cryo - 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