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Animal models are an extremely useful tool for the investigation of molecular mechanisms underlying these disorders. For psychiatric symptom assessment in animals, a meaningful behavioral phenotype is needed. Social behaviors constitute naturally occurring complex behaviors in rodents and can therefore serve as such a phenotype, contributing to\u00a0insights into disorder related molecular changes. In this\u00a0narrative review, we give a fundamental overview of social behaviors in laboratory rodents, as well as their underlying neuronal mechanisms and their assessment. Relevant behavioral and molecular changes in models for mood disorders are presented and an outlook on promising future directions is given.<\/jats:p>","DOI":"10.1515\/hsz-2023-0190","type":"journal-article","created":{"date-parts":[[2023,8,26]],"date-time":"2023-08-26T15:40:53Z","timestamp":1693064453000},"page":"939-950","source":"Crossref","is-referenced-by-count":7,"title":["Rodent models for mood disorders\u00a0\u2013 understanding molecular changes by investigating social behavior"],"prefix":"10.1515","volume":"404","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-5620-6364","authenticated-orcid":false,"given":"Patrick R.","family":"Reinhardt","sequence":"first","affiliation":[{"name":"Division of Experimental and Molecular Psychiatry, Department of Psychiatry, Psychotherapy and Preventive Medicine , LWL-University Hospital, Ruhr-University Bochum , D-44791 Bochum , Germany"},{"name":"International Graduate School of Neuroscience , Ruhr-University Bochum , D-44801 Bochum , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Candy D. 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