{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T04:46:02Z","timestamp":1790138762205,"version":"4.0.1"},"reference-count":29,"publisher":"Walter de Gruyter GmbH","issue":"11-12","funder":[{"name":"the National Key R&D Program of Ningxia Hui Autonomous Region of China","award":["21BEF02019"],"award-info":[{"award-number":["21BEF02019"]}]},{"DOI":"10.13039\/501100001809","name":"the National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["31602027"],"award-info":[{"award-number":["31602027"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"name":"the Natural Science Foundation of Ningxia Province","award":["2023AAC05052"],"award-info":[{"award-number":["2023AAC05052"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,12,17]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Heat stress impacts male reproduction in animal husbandry. Carnosic acid (CA), a potent antioxidant, mitigates oxidative stress and apoptosis. \u03b1B-crystallin, a small heat shock protein, regulates apoptosis and oxidative stress. This study examines the protective effects of CA on the testis in wild-type and \u03b1B-crystallin knockout mice under heat stress. CA pretreatment increased testosterone levels and preserved testicular structure in wild-type mice, but no changes in knockout mice. CA reduced Hsp27, Hsp70, and cleaved caspase-3 levels, while knockout mice showed increased cleaved caspase-3. These results suggest that CA protects the testis by modulating heat shock and apoptosis-related proteins.<\/jats:p>","DOI":"10.1515\/hsz-2023-0374","type":"journal-article","created":{"date-parts":[[2024,12,4]],"date-time":"2024-12-04T20:58:49Z","timestamp":1733345929000},"page":"745-749","source":"Crossref","is-referenced-by-count":3,"title":["Carnosic acid prevents heat stress-induced oxidative damage by regulating heat-shock proteins and apoptotic proteins in mouse testis"],"prefix":"10.1515","volume":"405","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4135-1141","authenticated-orcid":false,"given":"Sirui","family":"Liu","sequence":"first","affiliation":[{"name":"College of Veterinary Medicine , 70578 Nanjing Agricultural University , Nanjing , 210095 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"Jiaxin Wu","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine , 70578 Nanjing Agricultural University , Nanjing , 210095 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wanqing","family":"Liang","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine , 70578 Nanjing Agricultural University , Nanjing , 210095 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yinkun","family":"Liu","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine , 70578 Nanjing Agricultural University , Nanjing , 210095 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuangshuang","family":"Wan","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine , 70578 Nanjing Agricultural University , Nanjing , 210095 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shu","family":"Tang","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine , 70578 Nanjing Agricultural University , Nanjing , 210095 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2024,12,6]]},"reference":[{"key":"2025010813524305566_j_hsz-2023-0374_ref_001","doi-asserted-by":"crossref","unstructured":"Aldahhan, R.A. and Stanton, P.G. 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