{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T04:50:01Z","timestamp":1747198201802,"version":"3.40.5"},"reference-count":25,"publisher":"Walter de Gruyter GmbH","issue":"1-2","license":[{"start":{"date-parts":[[2020,3,1]],"date-time":"2020-03-01T00:00:00Z","timestamp":1583020800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,10,19]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p\/>\n               <jats:sec id=\"j_iss-2020-0014_abs_001\">\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>We describe the first application of intrauterine negative-pressure therapy (IU-NPT) for an early rupture of a uterine suture after a third caesarean section with consecutive peritonitis and sepsis. Because all four quadrants were affected by peritonitis, a laparotomy was performed on the 15th day after caesarean section. Abdominal negative-pressure wound therapy (A-NPWT) of the open abdomen was initiated. During the planned relaparotomy, a suture defect of the anterior uterine wall was identified and sutured. In the second relaparotomy, the suture appeared once more insufficient.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_iss-2020-0014_abs_002\">\n                  <jats:title>Case presentation<\/jats:title>\n                  <jats:p>For subsequent IU-NPT, we used an open-pore film drainage (OFD) consisting of a drainage tube wrapped in the double-layered film. The OFD was inserted into the uterine cavity via the uterine defect and IU-NPT was established together with A-NPT. With the next relaparotomy, local inflammation and peritonitis had been resolved completely. IU-NPT was continued transvaginally, the uterine defect was sutured, and the abdomen was closed. Vaginal IU-NPT was also discontinued after another eight days.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_iss-2020-0014_abs_003\">\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>By using IU-NPT, local infection control of the septic focus was achieved. The infectious uterine secretions were completely evacuated and no longer discharged into the abdominal cavity. As a result of the applied suction, the uterine cavity collapsed around the inlaid OFD. The total duration of IU-NPT was 11 days. The uterine defect was completely closed, and a hysterectomy was avoided. The patient was discharged four days after the end of IU-NPT. IU-NPT follows the same principles as those described for endoscopic negative-pressure wound therapy of the gastrointestinal tract.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1515\/iss-2020-0014","type":"journal-article","created":{"date-parts":[[2020,10,1]],"date-time":"2020-10-01T19:46:36Z","timestamp":1601581596000},"page":"67-73","source":"Crossref","is-referenced-by-count":2,"title":["Intrauterine negative-pressure therapy (IU-NPT) to treat peritonitis after caesarean section"],"prefix":"10.1515","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4493-0405","authenticated-orcid":false,"given":"Chris-Henrik","family":"Wulfert","sequence":"first","affiliation":[{"name":"Department of General Surgery , Bundeswehrkrankenhaus Hamburg , Hamburg , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian Theodor","family":"M\u00fcller","sequence":"additional","affiliation":[{"name":"Department for General, Abdominal, Thoracic and Vascular Surgery , Kath. Marienkrankenhaus Hamburg , Hamburg , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed Farouk","family":"Abdel-Kawi","sequence":"additional","affiliation":[{"name":"Department of Obstetrics , Kath. Marienkrankenhaus Hamburg , Hamburg , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wolfgang","family":"Schulze","sequence":"additional","affiliation":[{"name":"Department for General, Abdominal, Thoracic and Vascular Surgery , Kath. Marienkrankenhaus Hamburg , Hamburg , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henning","family":"Schmidt-Seithe","sequence":"additional","affiliation":[{"name":"Department for General, Abdominal, Thoracic and Vascular Surgery , Kath. Marienkrankenhaus Hamburg , Hamburg , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sonko","family":"Borstelmann","sequence":"additional","affiliation":[{"name":"Department of Obstetrics , Kath. Marienkrankenhaus Hamburg , Hamburg , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5534-1107","authenticated-orcid":false,"given":"Gunnar","family":"Loske","sequence":"additional","affiliation":[{"name":"Department for General, Abdominal, Thoracic and Vascular Surgery , Kath. Marienkrankenhaus Hamburg , Hamburg , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","published-online":{"date-parts":[[2020,10,1]]},"reference":[{"key":"2023033119441829967_j_iss-2020-0014_ref_001","doi-asserted-by":"crossref","unstructured":"Banwell, PE, Musgrave, M. Topical negative pressure therapy: mechanisms and indications. 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